Search Results - "Vandemheen, K L"

Methodological issues in therapeutic trials of COPD by Suissa, S, Ernst, P, Vandemheen, K. L, Aaron, S. D

“…The recent Towards a Revolution in COPD Health (TORCH) randomised trial replicated the findings of previous trials in chronic obstructive pulmonary disease…”
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Confirmation of asthma in an era of overdiagnosis by LUKS, V. P, VANDEMHEEN, K. L, AARON, S. D

“…It was recently shown that 30% of adults with a physician diagnosis of asthma did not have asthma when objectively assessed using a four-step algorithm…”
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Counting, analysing and reporting exacerbations of COPD in randomised controlled trials by Aaron, S D, Fergusson, D, Marks, G B, Suissa, S, Vandemheen, K L, Doucette, S, Maltais, F, Bourbeau, J F, Goldstein, R S, Balter, M, O'Donnell, D, Fitzgerald, M

“…Clinical trials measure exacerbations of chronic obstructive pulmonary disease (COPD) inconsistently. A study was undertaken to determine if different methods…”
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Predictors of pulmonary exacerbations in patients with cystic fibrosis infected with multi-resistant bacteria by Block, J K, Vandemheen, K L, Tullis, E, Fergusson, D, Doucette, S, Haase, D, Berthiaume, Y, Brown, N, Wilcox, P, Bye, P, Bell, S, Noseworthy, M, Pedder, L, Freitag, A, Paterson, N, Aaron, S D

“…Background: This study examined characteristics of adult and adolescent patients with cystic fibrosis (CF) to determine factors associated with an increased…”
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Cost effectiveness of therapy with combinations of long acting bronchodilators and inhaled steroids for treatment of COPD by Najafzadeh, M, Marra, C A, Sadatsafavi, M, Aaron, S D, Sullivan, S D, Vandemheen, K L, Jones, P W, Fitzgerald, J M

“…Little is known about the combination of different medications in chronic obstructive pulmonary disease (COPD). This study determined the cost effectiveness of…”
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Persistency of Pseudomonas aeruginosa in sputum cultures and clinical outcomes in adult patients with cystic fibrosis by Burkett, A., Vandemheen, K. L., Giesbrecht-Lewis, T., Ramotar, K., Ferris, W., Chan, F., Doucette, S., Fergusson, D., Aaron, S. D.

“…Our objective was to describe the natural history of infection with transmissible and unique strains of P. aeruginosa (PA) in adult CF patients and to…”
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Sex differences in the clinical presentation and management of airflow obstruction by Dales, R. E, Mehdizadeh, A, Aaron, S. D, Vandemheen, K. L, Clinch, J

“…The aim of the present study was to explore differences in the clinical expression, clinical diagnoses and management of airway diseases in a primary-care…”
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Sputum versus bronchoscopy for diagnosis of Pseudomonas aeruginosa biofilms in cystic fibrosis by Aaron, S.D, Kottachchi, D, Ferris, W.J, Vandemheen, K.L, St. Denis, M.L, Plouffe, A, Doucette, S.P, Saginur, R, Chan, F.T, Ramotar, K

“…The present authors hypothesised that bronchoscopy with protected specimen brush may sample biofilm-forming bacteria adherent to the airway wall, whereas…”
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The Canadian C-Spine Rule for Radiography in Alert and Stable Trauma Patients by Stiell, Ian G, Wells, George A, Vandemheen, Katherine L, Clement, Catherine M, Lesiuk, Howard, De Maio, Valerie J, Laupacis, Andreas, Schull, Michael, McKnight, R. Douglas, Verbeek, Richard, Brison, Robert, Cass, Daniel, Dreyer, Jonathan, Eisenhauer, Mary A, Greenberg, Gary H, MacPhail, Iain, Morrison, Laurie, Reardon, Mark, Worthington, James

“…CONTEXT High levels of variation and inefficiency exist in current clinical practice regarding use of cervical spine (C-spine) radiography in alert and stable…”
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Vasopressin versus epinephrine for inhospital cardiac arrest: a randomised controlled trial by Stiell, Ian G, Hébert, Paul C, Wells, George A, Vandemheen, Katherine L, Tang, Anthony SL, Higginson, Lyall AJ, Dreyer, Jonathan F, Clement, Catherine, Battram, Erica, Watpool, Irene, Mason, Sharon, Klassen, Terry, Weitzman, Brian N

“…Survival rates for cardiac arrest patients, both in and out of hospital, are poor. Results of a previous study suggest better outcomes for patients treated…”
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Exacerbation frequency and clinical outcomes in adult patients with cystic fibrosis by de Boer, Kaïssa, Vandemheen, Katherine L, Tullis, Elizabeth, Doucette, Steve, Fergusson, Dean, Freitag, Andreas, Paterson, Nigel, Jackson, Mary, Lougheed, M Diane, Kumar, Vijay, Aaron, Shawn D

“…Despite advances in treatment of cystic fibrosis (CF), pulmonary exacerbations remain common. The aim of this study was to determine if frequent pulmonary…”
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Early Diagnosis and Treatment of COPD and Asthma — A Randomized, Controlled Trial by Aaron, Shawn D., Vandemheen, Katherine L., Whitmore, G. Alex, Bergeron, Celine, Boulet, Louis-Philippe, Côté, Andréanne, McIvor, R. Andrew, Penz, Erika, Field, Stephen K., Lemière, Catherine, Mayers, Irvin, Bhutani, Mohit, Azher, Tanweer, Lougheed, M. Diane, Gupta, Samir, Ezer, Nicole, Licskai, Christopher J., Hernandez, Paul, Ainslie, Martha, Alvarez, Gonzalo G., Mulpuru, Sunita

“…Case finding for symptomatic adults with undiagnosed asthma or COPD was coupled with a randomized trial to compare pulmonologist-directed and usual care…”
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Overdiagnosis of asthma in obese and nonobese adults by Aaron, Shawn D, Vandemheen, Katherine L, Boulet, Louis-Philippe, McIvor, R Andrew, Fitzgerald, J Mark, Hernandez, Paul, Lemiere, Catherine, Sharma, Sat, Field, Stephen K, Alvarez, Gonzalo G, Dales, Robert E, Doucette, Steve, Fergusson, Dean

“…It is unclear whether asthma is overdiagnosed in developed countries, particularly among obese individuals, who may be more likely than nonobese people to…”
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B23 WHEN I GET HOME: CONFRONTING THE CHALLENGES OF COPD EXACERBATION: Discovery Of Novel Plasma Protein Biomarkers To Diagnose Acute COPD Exacerbations Using Multiple Reaction Monitoring Mass Spectrometry by Leung, J, Hollander, Z, Chen, V, Dai, D L Y, Tebbutt, S J, Aaron, S D, Vandemheen, K L, Rennard, S I, Woodruff, P G, Lazarus, S C, Connett, J, Coxson, H O, Miller, B, Borchers, C, McManus, B M, Ng, R T, Sin, D

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Effect of weight reduction on respiratory function and airway reactivity in obese women by Aaron, Shawn D, Fergusson, Dean, Dent, Robert, Chen, Yue, Vandemheen, Katherine L, Dales, Robert E

“…Population-based studies have documented an association between obesity and an increased prevalence of asthma in women. We prospectively studied 58 obese women…”
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Outpatient Oral Prednisone after Emergency Treatment of Chronic Obstructive Pulmonary Disease by Aaron, Shawn D, Vandemheen, Katherine L, Hebert, Paul, Dales, Robert, Stiell, Ian G, Ahuja, Jan, Dickinson, Garth, Brison, Robert, Rowe, Brian H, Dreyer, Jonathan, Yetisir, Elizabeth, Cass, Daniel, Wells, George

“…The optimal approach to the treatment of patients who are discharged from the emergency room after an exacerbation of chronic obstructive pulmonary disease is…”
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Combination antibiotic susceptibility testing to treat exacerbations of cystic fibrosis associated with multiresistant bacteria: a randomised, double-blind, controlled clinical trial by Aaron, Shawn D, Vandemheen, Katherine L, Ferris, Wendy, Fergusson, Dean, Tullis, Elizabeth, Haase, David, Berthiaume, Yves, Brown, Neil, Wilcox, Pearce, Yozghatlian, Veronica, Bye, Peter, Bell, Scott, Chan, Francis, Rose, Barbara, Jeanneret, Alphonse, Stephenson, Anne, Noseworthy, Mary, Freitag, Andreas, Paterson, Nigel, Doucette, Steve, Harbour, Colin, Ruel, Michel, MacDonald, Noni

“…We did a randomised, double-blind, controlled clinical trial to prospectively assess whether use of combination antibiotic susceptibility testing improved…”
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Epidemiological investigation and glycotyping of clinical Pseudomonas aeruginosa isolates from patients with cystic fibrosis by mass spectrometry: Association with multiple drug resistance by Altman, Eleonora, Wang, Zhan, Aaron, Shawn D., Liu, Xin, Vandemheen, Katherine L., Ferris, Wendy, Giesbrecht, Tracy, Li, Jianjun

“…The aim of the present investigation was to develop a novel approach for rapid identification and differentiation of Pseudomonas aeruginosa clones from…”
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Spirometry in the primary care setting: influence on clinical diagnosis and management of airflow obstruction by Dales, Robert E, Vandemheen, Katherine L, Clinch, Jennifer, Aaron, Shawn D

“…To determine if screening spirometry in the primary care setting influences the physician's diagnosis and management of obstructive lung disease. Diagnosis and…”
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The Canadian C-Spine rule performs better than unstructured physician judgment by Bandiera, Glen, Stiell, Ian G, Wells, George A, Clement, Catherine, De Maio, Valerie, Vandemheen, Katherine L, Greenberg, Gary H, Lesiuk, Howard, Brison, Robert, Cass, Daniel, Dreyer, Jonathan, Eisenhauer, Mary A, MacPhail, Iain, McKnight, R.Douglas, Morrison, Laurie, Reardon, Mark, Schull, Michael, Worthington, James

“…We compare the predictive accuracy of emergency physicians' unstructured clinical judgment to the Canadian C-Spine rule. This prospective multicenter cohort…”
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