Search Results - "Vandemeulebroucke, E"
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Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass
Published in Diabetologia (01-04-2010)“…Aims/hypothesis The aim of the study was to examine the 48 month outcome of treating recent-onset type 1 diabetic patients for 6 days with humanised…”
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In antibody-positive first-degree relatives of patients with type 1 diabetes, HLA-A24 and HLA-B18, but not HLA-B39, are predictors of impending diabetes with distinct HLA-DQ interactions
Published in Diabetologia (01-09-2013)“…Aims/hypothesis Secondary type 1 diabetes prevention trials require selection of participants with impending diabetes. HLA-A and - B alleles have been reported…”
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Emergence of Bluetongue Serotypes in Europe, Part 1: Description and Validation of Four Real-Time RT-PCR Assays for the Serotyping of Bluetongue Viruses BTV-1, BTV-6, BTV-8 and BTV-11
Published in Transboundary and emerging diseases (01-12-2009)“…The control of bluetongue virus (BTV) in Central-Western Europe is greatly complicated by the coexistence of several BTV serotypes. Rapid, sensitive and…”
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Transplacental Infection and Apparently Immunotolerance Induced by a Wild-type Bluetongue Virus Serotype 8 Natural Infection
Published in Transboundary and emerging diseases (01-10-2008)“…Summary Until recently, bluetongue (BT) virus (BTV) serotypes reportedly causing transplacental infections were all ascribed to the use of modified live virus…”
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Bluetongue Virus Serotype 8-Associated Congenital Hydranencephaly in Calves
Published in Transboundary and emerging diseases (01-09-2008)“…Hydranencephaly, the almost complete absence of the cerebral parenchyma, induced by infection with modified live bluetongue virus (BTV) crossing the placenta…”
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Experimental reproduction of bluetongue virus serotype 8 clinical disease in calves
Published in Veterinary microbiology (12-05-2009)“…Cattle are commonly subclinically infected following natural or experimental infection with bluetongue virus (BTV). The introduction of BTV serotype 8 (BTV-8)…”
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Hyperglycaemic clamp test for diabetes risk assessment in IA-2-antibody-positive relatives of type 1 diabetic patients
Published in Diabetologia (2010)“…Aims/hypothesis The aim of the study was to investigate the use of hyperglycaemic clamp tests to identify individuals who will develop diabetes among…”
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Bluetongue Virus Detection by Real-Time RT-PCR in Culicoides Captured During the 2006 Epizootic in Belgium and Development of an Internal Control
Published in Transboundary and emerging diseases (01-06-2009)“…After the emergence of bluetongue (BT) in Belgium in 2006, two types of entomological surveys were initiated, the one to identify the local vector species, and…”
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Proinsulin levels and the proinsulin:C-peptide ratio complement autoantibody measurement for predicting type 1 diabetes
Published in Diabetologia (01-11-2005)“…We investigated whether random proinsulin levels and proinsulin:C-peptide ratio (PI:C) complement immune and genetic markers for identifying relatives at high…”
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Insulin treatment in IA-2A-positive relatives of type 1 diabetic patients
Published in Diabetes & metabolism (01-09-2009)“…Abstract Aims We examined whether parenteral regular insulin can prevent diabetes in IA-2 antibody-positive (IA-2A+) relatives of type 1 diabetic patients,…”
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Transplacental bluetongue infection in cattle
Published in Veterinary record (26-04-2008)“…Spleens from 68 aborted fetuses, and edta blood samples and sera from 109 newborn calves received between December 15 and March 15 were tested using a…”
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Emergence of Bluetongue Serotypes in Europe, Part 2: The Occurrence of a BTV-11 Strain in Belgium
Published in Transboundary and emerging diseases (01-12-2009)“…An EDTA-blood sample from a cow without clinical signs, which gave early birth to a newborn calf that died soon after delivery, was shown to be positive for…”
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Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes
Published in Diabetologia (01-04-2005)“…Prevention trials in first-degree relatives of type 1 diabetic patients are hampered by large interindividual differences in progression rate to diabetes. We…”
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IA-2 autoantibodies predict impending Type I diabetes in siblings of patients
Published in Diabetologia (01-12-2002)“…Multiple islet autoantibody positivity is currently believed to best predict progression to Type I (insulin-dependent) diabetes mellitus. We compared its…”
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Effect of pooling and multiplexing on the detection of bluetongue virus RNA by real-time RT-PCR
Published in Journal of virological methods (01-09-2008)“…Real-time RT-PCR (RT-qPCR) was used routinely for laboratory diagnosis during the 2006/2007 bluetongue virus (BTV) serotype 8 epidemic. In the present study…”
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Adiponectin levels do not predict clinical onset of type 1 diabetes in antibody-positive relatives
Published in Diabetologia (01-10-2007)“…Aims/Hypothesis Insulin resistance has been proposed as a risk factor for type 1 diabetes. We investigated whether adiponectin, an insulin sensitiser, can…”
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Silent iodine prophylaxis in Western Europe only partly corrects iodine deficiency; the case of Belgium
Published in European journal of endocrinology (01-08-2000)“…Belgium is one of the Western European countries in which no program of iodine-deficiency correction using iodized salt has been implemented, in spite of…”
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Recurrent severe thiamine deficiency following bariatric surgery in pregnant women
Published in Revue médicale de Bruxelles (2023)Get full text
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Insulin Needs after CD3-Antibody Therapy in New-Onset Type 1 Diabetes
Published in The New England journal of medicine (23-06-2005)“…This multicenter, phase 2, placebo-controlled trial involved the use of a humanized antibody — ChAglyCD3 — directed against CD3 in the treatment of new-onset…”
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Microscopic diagnosis of blood parasites following a cytoconcentration technique
Published in The American journal of tropical medicine and hygiene (01-12-1997)“…An isotonic fixative (formalin and thimerosal) solution, with a saponin additive to lyse erythrocytes and platelets, has been developed. The formalin and…”
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