Search Results - "Vandelli, M A"

Targeting the central nervous system: In vivo experiments with peptide-derivatized nanoparticles loaded with Loperamide and Rhodamine-123 by Tosi, G., Costantino, L., Rivasi, F., Ruozi, B., Leo, E., Vergoni, A.V., Tacchi, R., Bertolini, A., Vandelli, M.A., Forni, F.

“…Polymeric nanoparticles (Np) represent one of the most innovative non-invasive approaches for the drug delivery to the central nervous system (CNS). It is…”
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Sialic acid and glycopeptides conjugated PLGA nanoparticles for central nervous system targeting: In vivo pharmacological evidence and biodistribution by Tosi, G., Vergoni, A.V., Ruozi, B., Bondioli, L., Badiali, L., Rivasi, F., Costantino, L., Forni, F., Vandelli, M.A.

“…Polymeric nanoparticles (Np) have been considered as strategic carriers for brain targeting. Specific ligands on the surface allowed the Np to cross the…”
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Exploiting Bacterial Pathways for BBB Crossing with PLGA Nanoparticles Modified with a Mutated Form of Diphtheria Toxin (CRM197): In Vivo Experiments by Tosi, G, Vilella, A, Veratti, P, Belletti, D, Pederzoli, F, Ruozi, B, Vandelli, M. A, Zoli, M, Forni, F

“…Drugs can be targeted to the brain using polymeric nanoparticles (NPs) engineered on their surface with ligands able to allow crossing of the blood–brain…”
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Gelatin microspheres crosslinked with d, l-glyceraldehyde as a potential drug delivery system: preparation, characterisation, in vitro and in vivo studies by Vandelli, M.A., Rivasi, F., Guerra, P., Forni, F., Arletti, R.

“…To overcome the restriction in using crosslinked gelatin in the pharmaceutical field, d, l-glyceraldehyde (GAL), a non-toxic crosslinking agent, was proposed…”
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NIR-labeled nanoparticles engineered for brain targeting: in vivo optical imaging application and fluorescent microscopy evidences by Tosi, G., Bondioli, L., Ruozi, B., Badiali, L., Severini, G. M., Biffi, S., De Vita, A., Bortot, B., Dolcetta, D., Forni, F., Vandelli, M. A.

“…The presence of the blood–brain barrier (BBB) makes extremely difficult to develop efficacious strategies for targeting contrast agents and delivering drugs…”
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The loading of labelled antibody-engineered nanoparticles with Indinavir increases its in vitro efficacy against Cryptosporidium parvum by Bondioli, L, Ludovisi, A, Tosi, G, Ruozi, B, Forni, F, Pozio, E, Vandelli, M A, Gómez-Morales, M A

“…There is much evidence to indicate the ability of Indinavir (IND) to reduce Cryptosporidium parvum infection in both in vitro and in vivo models. However,…”
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Potential use of polymeric nanoparticles for drug delivery across the blood-brain barrier by Tosi, G, Bortot, B, Ruozi, B, Dolcetta, D, Vandelli, M A, Forni, F, Severini, G M

“…Nanomedicine is certainly one of the scientific and technological challenges of the coming years. In particular, biodegradable nanoparticles formulated from…”
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Conjugated poly( D, L-lactide- co-glycolide) for the preparation of in vivo detectable nanoparticles by Tosi, G., Rivasi, F., Gandolfi, F., Costantino, L., Vandelli, M.A., Forni, F.

“…Cellular localization of nanoparticles (Np) represents an important target in the understanding of their distribution after endovenous injection. The need of…”
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Apoferritin nanocage as streptomycin drug reservoir: Technological optimization of a new drug delivery system by Ruozi, B., Veratti, P., Vandelli, M.A., Tombesi, A., Tonelli, M., Forni, F., Pederzoli, F., Belletti, D., Tosi, G.

“…[Display omitted] The aim of this study is to formulate and characterize streptomycin-loaded apoferritin nanoparticles (ApoStrep NPs) for their potential…”
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EXPLOITING THE VERSATILITY OF CHOLESTEROL IN NANOPARTICLES FORMULATION by Belletti, D., Grabrucker, A.M., Pederzoli, F., Menrath, I., Cappello, V., Vandelli, M.A., Forni, F., Tosi, G., Ruozi, B.

“…[Display omitted] The biocompatibility of polymers, lipids and surfactants used to formulate is crucial for the safe and sustainable development of…”
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Poly(lactic acid) microspheres for the sustained release of antiischemic agents by Dalpiaz, A, Scatturin, A, Pavan, B, Biondi, C, Vandelli, M.A, Forni, F

“…We report a preliminary study evaluating the encapsulation modalities in microparticles of the antiischemic drug N 6-cyclopentyladenosine (CPA). The effects of…”
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Nanoimaging: photophysical and pharmaceutical characterization of poly-lactide-co-glycolide nanoparticles engineered with quantum dots by Pederzoli, F, Ruozi, B, Pracucci, E, Signore, G, Zapparoli, Mauro, Forni, F, Vandelli, M A, Ratto, G, Tosi, G

“…Quantum dots (QDs) and polymeric nanoparticles (NPs) are considered good binomials for the development of multifunctional nanomedicines for multimodal imaging…”
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Nutlin-3 loaded nanocarriers: Preparation, characterization and in vitro antineoplastic effect against primary effusion lymphoma by Belletti, D., Tosi, G., Riva, G., Lagreca, I., Galliania, M., Luppi, M., Vandelli, M.A., Forni, F., Ruozi, B.

“…[Display omitted] In this investigation, Nutlin-3 (Nut3), a novel antitumor drug with low water solubility (<0.1mg/L at 25°C), was loaded into liposomes…”
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Complexation of the sunscreen agent, butyl-methoxydibenzoylmethane, with hydroxypropyl-β-cyclodextrin by Scalia, S., Villani, S., Scatturin, A., Vandelli, M.A., Forni, F.

“…The interaction between the sunscreen, butyl-methoxydibenzoylmethane (BM-DBM), and parent and modified α-, β- or γ-cyclodextrins was investigated in water by…”
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Nanotechnology and Alzheimer's disease: what has been done and what to do by Ruozi, B, Belletti, D, Pederzoli, F, Veratti, P, Forni, F, Vandelli, M A, Tosi, G

“…Up to date, Alzheimer's Disease (AD) is considered as an "urgency" for public health, since it represents one of the most dramatic causes of death in adults…”
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Nanoparticles loaded with Nutlin-3 display cytotoxicity towards p53(wild-type) JVM-2 but not towards p53(mutated) BJAB leukemic cells by Voltan, R, Secchiero, P, Ruozi, B, Caruso, L, Forni, F, Palomba, M, Zauli, G, Vandelli, M A

“…The small molecule Nutlin-3 is a potent antagonist of the murine double minute 2 (MDM2)/p53 interaction exhibiting promising therapeutic anti-cancer activity…”
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Synthesis and characterisation of poly( d, l-lactic acid)–idoxuridine conjugate by Rimoli, M.G, Avallone, L, de Caprariis, P, Galeone, A, Forni, F, Vandelli, M.A

“…A new polymeric prodrug was prepared coupling 5-iodo-2′-deoxyuridine (IDU) to poly( d, l-lactic acid) (PLA) via a succinic acid spacer. The PLA–IDU conjugate…”
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Neurotrophic factors and neurodegenerative diseases: a delivery issue by Ruozi, B, Belletti, D, Bondioli, L, De Vita, A, Forni, F, Vandelli, M A, Tosi, G

“…Neurotrophic factors (NTFs) represent one of the most stimulating challenge in neurodegenerative diseases, due to their potential in neurorestoring and…”
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Anticancer drug-loaded quantum dots engineered polymeric nanoparticles: Diagnosis/therapy combined approach by Belletti, D., Riva, G., Luppi, M., Tosi, G., Forni, F., Vandelli, M.A., Ruozi, B., Pederzoli, F.

“…Primary Effusion Lymphoma (PEL) is an HHV-8-related non Hodgkin lymphoma localized in body cavities (as pleural, peritoneal and pericardial) presenting…”
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Antineoplastic effects of liposomal short interfering RNA treatment targeting BLIMP1/PRDM1 in primary effusion lymphoma by Riva, Giovanni, Lagreca, Ivana, Mattiolo, Adriana, Belletti, Daniela, Lignitto, Laura, Barozzi, Patrizia, Ruozi, Barbara, Vallerini, Daniela, Quadrelli, Chiara, Corradini, Giorgia, Forghieri, Fabio, Marasca, Roberto, Narni, Franco, Tosi, Giovanni, Forni, Flavio, Vandelli, Maria Angela, Amadori, Alberto, Chieco-Bianchi, Luigi, Potenza, Leonardo, Calabrò, Maria Luisa, Luppi, Mario

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