Search Results - "VandeBunte, Anna"
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Regional Vulnerability of the Corpus Callosum in the Context of Cardiovascular Risk
Published in Journal of geriatric psychiatry and neurology (01-09-2023)“…Many factors outside of cardiovascular health can impact the structure of white matter. Identification of reliable and clinically meaningful biomarkers of the…”
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Data-driven physical actigraphy patterns relate to cognitive and vascular health in older adults
Published in Experimental gerontology (01-07-2023)“…Health benefits of physical activity (PA) are well known; however, specific PA patterns that relate most strongly to cognitive aging outcomes are poorly…”
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Multimodal lifestyle engagement patterns support cognitive stability beyond neuropathological burden
Published in Alzheimer's research & therapy (18-12-2023)“…Modifiable lifestyle behaviors account for a large proportion of dementia risk. However, the combined contributions of multidomain lifestyle patterns to…”
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Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers
Published in Alzheimer's & dementia (01-10-2024)“…INTRODUCTION Cardiovascular health is important for brain aging, yet its role in the clinical manifestation of autosomal dominant or atypical forms of dementia…”
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Physical activity measurement in older adults: Wearables versus self-report
Published in Frontiers in digital health (31-08-2022)“…Physical activity (PA) is associated with preserved age-related body and brain health. However, PA quantification can vary. Commercial-grade wearable monitors…”
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Wearable Use in an Observational Study Among Older Adults: Adherence, Feasibility, and Effects of Clinicodemographic Factors
Published in Frontiers in digital health (10-06-2022)“…Wearables have great potential to improve monitoring and delivery of physical activity interventions to older adults with downstream benefits to multisystem…”
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Microglial Correlates of Late Life Physical Activity: Relationship with Synaptic and Cognitive Aging in Older Adults
Published in The Journal of neuroscience (12-01-2022)“…Physical activity relates to reduced dementia risk, but the cellular and molecular mechanisms are unknown. We translated animal and studies demonstrating a…”
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Late‐life physical activity relates to brain tissue synaptic integrity markers in older adults
Published in Alzheimer's & dementia (01-11-2022)“…Introduction Physical activity (PA) is widely recommended for age‐related brain health, yet its neurobiology is not well understood. Animal models indicate PA…”
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Defining physical activity: A comparison of actigraphy monitoring and self‐report measures
Published in Alzheimer's & dementia (01-12-2021)“…Background Physical activity (PA) helps preserve age‐related brain health. However, PA is a broad construct and its operationalization can vary. Actigraphy…”
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Latent profiles of physical actigraphy patterns among older adults: Differential relationships with cognition and vascular burden by sex
Published in Alzheimer's & dementia (01-12-2022)“…Background Physical activity (PA) is well‐known to benefit cognition and vascular health, yet it is less clear how specific PA patterns relate to cognitive and…”
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Plasma rejuvenation factor GDF11 associates with amyloid‐related cognitive decline in older adults across the Alzheimer’s Disease spectrum
Published in Alzheimer's & dementia (01-12-2023)“…Background Through studies of animal heterochronic parabiosis (fusion of juvenile and older adult animal circulatory systems), growth differentiation factor 11…”
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Physical Activity Relates to Lower Astrocytic Activation and Axonal Breakdown in Clinically Normal Older Adults
Published in Alzheimer's & dementia (01-12-2022)“…Background Physical activity is associated with >30% reduced risk of dementia. However, the biological mechanisms underlying exercise as a protective factor…”
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Blood‐brain barrier dysfunction is associated with A/T/N biomarkers and cognition in the aging brain
Published in Alzheimer's & dementia (01-12-2022)“…Background Age‐associated dysfunction of the blood‐brain barrier results in increased non‐specific permeability of the barrier and “leakage” of blood proteins…”
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Alzheimer’s Disease Proteinopathy and Synaptic Integrity: The Protective Role of Physical Activity
Published in Alzheimer's & dementia (01-12-2022)“…Background Alzheimer’s disease (AD) proteinopathy levels are associated with greater synaptic dysfunction markers in brain tissue and cerebrospinal fluid…”
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Moderating role of physical activity on hippocampal iron deposition and memory outcomes in typically aging older adults
Published in Neurobiology of aging (01-11-2023)“…Physical activity (PA) is linked to better cognitive and brain health, though its mechanisms are unknown. While brain iron is essential for normal function,…”
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Life’s Simple 7 Relates to Better Cognitive and Brain Health in Individuals with Autosomal Dominant Frontotemporal Dementia
Published in Alzheimer's & dementia (01-12-2023)“…Background Cardiovascular health plays an important role in brain aging; yet its role in development of autosomal dominant forms of dementia and frontotemporal…”
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Roles of physical activity and diet in cognitive aging: is more better?
Published in Clinical neuropsychologist (17-02-2023)“…Objective: To determine the synergistic effects of nutrition, specifically adherence to the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND)…”
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Association of Physical Activity With Neurofilament Light Chain Trajectories in Autosomal Dominant Frontotemporal Lobar Degeneration Variant Carriers
Published in JAMA neurology (01-01-2023)“…Physical activity is associated with cognitive health, even in autosomal dominant forms of dementia. Higher physical activity is associated with slowed…”
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