Search Results - "Vandal, Omar"

Acid Resistance in Mycobacterium tuberculosis by VANDAL, Omar H, NATHAN, Carl F, EHRT, Sabine

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A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis by Ehrt, Sabine, Vandal, Omar H, Schnappinger, Dirk, Pierini, Lynda M, Nathan, Carl F

“…Acidification of the phagosome is considered to be a major mechanism used by macrophages against bacteria, including Mycobacterium tuberculosis (Mtb). Mtb…”
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Host-Directed Therapeutics for Tuberculosis: Can We Harness the Host? by Hawn, Thomas R, Matheson, Alastair I, Maley, Stephen N, Vandal, Omar

“…Classifications Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice by Goodsmith, Nichole, Guo, Xinzheng V, Vandal, Omar H, Vaubourgeix, Julien, Wang, Ruojun, Botella, Hélène, Song, Shuang, Bhatt, Kamlesh, Liba, Amir, Salgame, Padmini, Schnappinger, Dirk, Ehrt, Sabine

“…The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense…”
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Acid-Susceptible Mutants of Mycobacterium tuberculosis Share Hypersusceptibility to Cell Wall and Oxidative Stress and to the Host Environment by VANDAL, Omar H, ROBERTS, Julia A, ODAIRA, Toshiko, SCHNAPPINGER, Dirk, NATHAN, Carl F, EHRT, Sabine

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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TCR affinity for self-ligands influences the development and function of encephalitogenic T cells by Li, Jianwei, Vandal, Omar, Sant'Angelo, Derek B

“…The specificity and affinity of self-reactive T cells is likely to impact the development of autoimmune-disease causing T cells in the thymus as well as their…”
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Cytosolic Phospholipase A₂ Enzymes Are Not Required by Mouse Bone Marrow-Derived Macrophages for the Control of Mycobacterium tuberculosis In Vitro by Vandal, Omar H, Gelb, Michael H, Ehrt, Sabine, Nathan, Carl F

“…During the course of infection Mycobacterium tuberculosis predominantly resides within macrophages, where it encounters and is often able to resist the…”
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Killing the hypnozoite - drug discovery approaches to prevent relapse in Plasmodium vivax by Campo, Brice, Vandal, Omar, Wesche, David L., Burrows, Jeremy N.

“…The eradication of malaria will only be possible if effective, well-tolerated medicines kill hypnozoites in vivax and ovale malaria, and thus prevent relapses…”
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Selective killing of nonreplicating mycobacteria by Bryk, Ruslana, Gold, Benjamin, Venugopal, Aditya, Singh, Jasbir, Samy, Raghu, Pupek, Krzysztof, Cao, Hua, Popescu, Carmen, Gurney, Mark, Hotha, Srinivas, Cherian, Joseph, Rhee, Kyu, Ly, Lan, Converse, Paul J, Ehrt, Sabine, Vandal, Omar, Jiang, Xiuju, Schneider, Jean, Lin, Gang, Nathan, Carl

“…Antibiotics are typically more effective against replicating rather than nonreplicating bacteria. However, a major need in global health is to eradicate…”
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Structural Insight into Serine Protease Rv3671c that Protects M. tuberculosis from Oxidative and Acidic Stress by Biswas, Tapan, Small, Jennifer, Vandal, Omar, Odaira, Toshiko, Deng, Haiteng, Ehrt, Sabine, Tsodikov, Oleg V.

“…Rv3671c, a putative serine protease, is crucial for persistence of Mycobacterium tuberculosis in the hostile environment of the phagosome. We show that Rv3671c…”
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Substrate Specificity of MarP, a Periplasmic Protease Required for Resistance to Acid and Oxidative Stress in Mycobacterium tuberculosis by Small, Jennifer L., O'Donoghue, Anthony J., Boritsch, Eva C., Tsodikov, Oleg V., Knudsen, Giselle M., Vandal, Omar, Craik, Charles S., Ehrt, Sabine

“…The transmembrane serine protease MarP is important for pH homeostasis in Mycobacterium tuberculosis (Mtb). Previous structural studies revealed that MarP…”
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A philosophy of anti-infectives as a guide in the search for new drugs for tuberculosis by Nathan, Carl, Gold, Ben, Lin, Gang, Stegman, Melanie, de Carvalho, Luiz Pedro Sorio, Vandal, Omar, Venugopal, Aditya, Bryk, Ruslana

“…Summary How we develop antibiotics is shaped by how we view infectious disease. Given the urgent need for new chemotherapeutics for tuberculosis and other…”
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Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice: e1004645 by Goodsmith, Nichole, Guo, Xinzheng V, Vandal, Omar H, Vaubourgeix, Julien, Wang, Ruojun, Botella, Hélène, Song, Shuang, Bhatt, Kamlesh, Liba, Amir, Salgame, Padmini, Schnappinger, Dirk, Ehrt, Sabine

“…The identification of Mycobacterium tuberculosis genes necessary for persistence in vivo provides insight into bacterial biology as well as host defense…”
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Detection and treatment of subclinical tuberculosis by Robertson, Brian D, Altmann, Danny, Barry, Clif, Bishai, Bill, Cole, Stewart, Thomas Dick, Duncan, Ken, Dye, Chris, Ehrt, Sabine, Esmail, Hanif, Flynn, JoAnne, Hafner, Richard, Handley, Gray, Hanekom, Willem, van Helden, Paul, Kaplan, Gilla, Kaufmann, Stefan H.E, Kim, Peter, Lienhardt, Christian, Mizrahi, Valerie, Rubin, Eric, Schnappinger, Dirk, Sherman, David, Thole, Jelle, Vandal, Omar, Walzl, Gerhard, Warner, Digby, Wilkinson, Robert, Young, Douglas

“…Summary Reduction of active disease by preventive therapy has the potential to make an important contribution towards the goal of tuberculosis (TB)…”
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Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets by Lafuente, Maria Jose, Guidelli-Disse, Sonja, Selenski, Carolyn, Lelievre, Joel, Willson, Timothy, Gamo, Francisco Javier, Drewes, Gerard, Vandal, Omar, Ballell-Pages, Luis

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A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis by Vandal, Omar H, Pierini, Lynda M, Schnappinger, Dirk, Nathan, Carl F, Ehrt, Sabine

“…Acidification of the phagosome is considered to be a major mechanism used by macrophages against bacteria, including Mycobacterium tuberculosis (Mtb). Mtb…”
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Cytosolic Phospholipase A sub(2) Enzymes Are Not Required by Mouse Bone Marrow-Derived Macrophages for the Control of Mycobacterium tuberculosis In Vitro by Vandal, Omar H, Gelb, Michael H, Ehrt, Sabine, Nathan, Carl F

“…During the course of infection Mycobacterium tuberculosis predominantly resides within macrophages, where it encounters and is often able to resist the…”
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Cytosolic Phospholipase A 2 Enzymes Are Not Required by Mouse Bone Marrow-Derived Macrophages for the Control of Mycobacterium tuberculosis In Vitro by Vandal, Omar H., Gelb, Michael H., Ehrt, Sabine, Nathan, Carl F.

“…During the course of infection Mycobacterium tuberculosis predominantly resides within macrophages, where it encounters and is often able to resist the…”
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Mycobacterium tuberculosis and the macrophage: Host defenses and bacterial resistance by Vandal, Omar Haider

“…During the course of infection Mycobacterium tuberculosis (Mtb) predominantly resides within macrophages, where it encounters and is often able to resist the…”
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Mycobacterium tuberculosis and the macrophage: Host defenses and bacterial resistance by Vandal, Omar Haider

“…During the course of infection Mycobacterium tuberculosis (Mtb) predominantly resides within macrophages, where it encounters and is often able to resist the…”
Get full text