Search Results - "Vance, Krysten"

Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation by Somerville, Tim Dd, Biffi, Giulia, Daßler-Plenker, Juliane, Hur, Stella K, He, Xue-Yan, Vance, Krysten E, Miyabayashi, Koji, Xu, Yali, Maia-Silva, Diogo, Klingbeil, Olaf, Demerdash, Osama E, Preall, Jonathan B, Hollingsworth, Michael A, Egeblad, Mikala, Tuveson, David A, Vakoc, Christopher R

“…A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we…”
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An intravenous pancreatic cancer therapeutic: Characterization of CRISPR/Cas9n-modified Clostridium novyi-Non Toxic by Dailey, Kaitlin M, Small, James M, Pullan, Jessica E, Winfree, Seth, Vance, Krysten E, Orr, Megan, Mallik, Sanku, Bayles, Kenneth W, Hollingsworth, Michael A, Brooks, Amanda E

“…Clostridium novyi has demonstrated selective efficacy against solid tumors largely due to the microenvironment contained within dense tumor cores. The core of…”
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IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer by Markov, Spas Dimitrov, Caffrey, Thomas C, O'Connell, Kelly A, Grunkemeyer, James A, Shin, Simon, Hanson, Ryan, Patil, Prathamesh P, Shukla, Surendra K, Gonzalez, Daisy, Crawford, Ayrianne J, Vance, Krysten E, Huang, Ying, Eberle, Kirsten C, Radhakrishnan, Prakash, Grandgenett, Paul M, Singh, Pankaj K, Madiyalakan, Ragupathy, Daniels-Wells, Tracy R, Penichet, Manuel L, Nicodemus, Christopher F, Poole, Jill A, Jaffee, Elizabeth M, Hollingsworth, Michael A, Mehla, Kamiya

“…Pancreatic ductal adenocarcinoma (PDAC) represents 3% of all cancer cases and 7% of all cancer deaths in the United States. Late diagnosis and inadequate…”
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Abstract 3760: Identifying site-specific disparities in the tumor microenvironment of primary and metastatic disease by Vance, Krysten E., Hollingsworth, Micheal A., Grandgenett, Paul

“…The tumor microenvironment (TME), or all cellular and molecular components in and around the tumor, has a well-documented impact on cancer cell proliferation,…”
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Immune-epithelial Niches Are Dose-Dependent in Calcineurin Inhibitor Nephrotoxicity: TH-PO655 by Winfree, Seth, Mcandrews, Kyle, Vance, Krysten, Kubik, Gregory S., Zmijewska, Anna A., Eudy, James, Mannon, Roslyn B.

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Characterization of Immune Infiltrate Along the Leading Edge of Differentiated Thyroid Cancer by Kotwal, Anupam, Vance, Krysten, Hajric, Kemal, Yuil-Valdes, Ana, Swanson, Benjamin, Martinez Duarte, Ernesto, Shats, Oleg, Hollingsworth, Michael, Band, Hamid, Goldner, Whitney

“…: Although the impact of tumor-immune infiltrate has been reported on differentiated thyroid cancer (DTC) behavior, the expression of immune checkpoints…”
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Abstract PO-037: Development of an RGD CRISPR-modified Clostridium novyi NT spores as an intravenous oncotherapy by Dailey, Kaitlin M., Vance, Krysten, McAndrews, Kyle, Jacobson, Reed I., Delgado, Jandro, Johnson, Paige R., Woolery, Taylor M., Orr, Megan, Kim, Jiha, Mallik, Sanku, Bayles, Kenneth W., Hollingsworth, Michael A., Brooks, Amanda E.

“…The efficacy of current oncotherapeutics is largely limited by an inability to access avascular tissues, which is in part responsible for forty years of…”
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A simple fluorescent assay for the discovery of protein-protein interaction inhibitors by Al-Mugotir, Mona, Kolar, Carol, Vance, Krysten, Kelly, David L., Natarajan, Amarnath, Borgstahl, Gloria E.O.

“…Due to the therapeutic potential of targeting protein-protein interactions (PPIs) there is a need for easily executed assays to perform high throughput…”
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IgE-based therapeutic combination enhances anti-tumor response in preclinical models of pancreatic cancer by Markov, Spas Dimitrov, Caffrey, Thomas C., O’Connell, Kelly A., Grunkemeyer, James A., Shin, Simon, Hanson, Ryan, Patil, Prathamesh P., Shukla, Surendra K., Gonzalez, Daisy, Crawford, Ayrianne J., Vance, Krysten E., Huang, Ying, Eberle, Kirsten C., Radhakrishnan, Prakash, Grandgenett, Paul M., Singh, Pankaj K., Madiyalakan, Ragupathy, Daniels-Wells, Tracy R., Penichet, Manuel L., Nicodemus, Christopher F., Poole, Jill A., Jaffee, Elizabeth M., Hollingsworth, Michael A., Mehla, Kamiya

“…Pancreatic ductal adenocarcinoma (PDAC) represents 3% of all cancer cases and 7% of all cancer deaths in the United States. Late diagnosis and inadequate…”
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RF11 | PSAT272 Suppressive Tumor Immune Microenvironment is Associated with Aggressive Differentiated Thyroid Cancer by Kotwal, Anupam, Hajric, Kemal, Vance, Krysten, Duarte, Ernesto M, Yuil-Valdes, Ana, Hollingsworth, Michael, Ganti, Apar, Band, Hamid, Swanson, Benjamin, Bennett, Robert, Goldner, Whitney

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Machine learning analyses of highly-multiplexed immunofluorescence identifies distinct tumor and stromal cell populations in primary pancreatic tumors by Vance, Krysten, Alitinok, Alphan, Winfree, Seth, Jensen-Smith, Heather, Swanson, Benjamin J, Grandgenett, Paul M, Klute, Kelsey A, Crichton, Daniel J, Hollingsworth, Michael A

“…Pancreatic ductal adenocarcinoma (PDAC) is a formidable challenge for patients and clinicians. To analyze the distribution of 31 different markers in tumor and…”
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An intravenous pancreatic cancer therapeutic: Characterization of CRISPR/Cas9n-modified Clostridium novyi-Non Toxic by Kaitlin M Dailey, James M Small, Jessica E Pullan, Seth Winfree, Krysten E Vance, Megan Orr, Sanku Mallik, Kenneth W Bayles, Michael A Hollingsworth, Amanda E Brooks

“…Clostridium novyi has demonstrated selective efficacy against solid tumors largely due to the microenvironment contained within dense tumor cores. The core of…”
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