Search Results - "Vance, Katie M"

Glutamate receptor ion channels: structure, regulation, and function by Traynelis, Stephen F, Wollmuth, Lonnie P, McBain, Chris J, Menniti, Frank S, Vance, Katie M, Ogden, Kevin K, Hansen, Kasper B, Yuan, Hongjie, Myers, Scott J, Dingledine, Ray

“…The mammalian ionotropic glutamate receptor family encodes 18 gene products that coassemble to form ligand-gated ion channels containing an agonist recognition…”
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Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain by Yuan, Hongjie, Hansen, Kasper B, Vance, Katie M, Ogden, Kevin K, Traynelis, Stephen F

“…NMDA receptors comprised of different NR2 subunits exhibit strikingly unique biophysical and pharmacological properties. Here, we report that the extracellular…”
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NMDA Receptors Containing the GluN2D Subunit Control Neuronal Function in the Subthalamic Nucleus by Swanger, Sharon A, Vance, Katie M, Pare, Jean-François, Sotty, Florence, Fog, Karina, Smith, Yoland, Traynelis, Stephen F

“…The GluN2D subunit of the NMDA receptor is prominently expressed in the basal ganglia and associated brainstem nuclei, including the subthalamic nucleus (STN),…”
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Palliative care reduces emergency room visits and total hospital days among patients with metastatic HPB and GI cancers by Billiot, Angelle A., Danos, Denise M., Stevens, Jenny, Vance, Katie M., Raven, Mary C., Lyons, John M.

“…Palliative care services (PCS) have improved quality of life for patients across various cancer subtypes. Minimal data exists regarding PCSfor metastatic…”
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Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors by Vance, Katie M., Simorowski, Noriko, Traynelis, Stephen F., Furukawa, Hiro

“…N -methyl- D -aspartate (NMDA) receptors belong to the family of ionotropic glutamate receptors that mediate a majority of excitatory synaptic transmission…”
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A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors by Traynelis, Stephen F, Mullasseril, Praseeda, Hansen, Kasper B, Vance, Katie M, Ogden, Kevin K, Yuan, Hongjie, Kurtkaya, Natalie L, Santangelo, Rose, Orr, Anna G, Le, Phuong, Vellano, Kimberly M, Liotta, Dennis C

“…NMDA receptors are tetrameric complexes of NR1 and NR2A–D subunits that mediate excitatory synaptic transmission and have a role in neurological disorders. In…”
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Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators by Acker, Timothy M, Yuan, Hongjie, Hansen, Kasper B, Vance, Katie M, Ogden, Kevin K, Jensen, Henrik S, Burger, Pieter B, Mullasseril, Praseeda, Snyder, James P, Liotta, Dennis C, Traynelis, Stephen F

“…The compound 4-(5-(4-bromophenyl)-3-(6-methyl-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic acid (DQP-1105) is a…”
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St. John’s Wort enhances the synaptic activity of the nucleus of the solitary tract by Vance, Katie M., Ph.D, Ribnicky, David M., Ph.D, Hermann, Gerlinda E., Ph.D, Rogers, Richard C., Ph.D

“…Abstract Objective St. John’s Wort (SJW) extract, which is commonly used to treat depression, inhibits the reuptake of several neurotransmitters, including…”
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The Serine Protease Plasmin Cleaves the Amino-terminal Domain of the NR2A Subunit to Relieve Zinc Inhibition of the N-Methyl-d-aspartate Receptors by Yuan, Hongjie, Vance, Katie M., Junge, Candice E., Geballe, Matthew T., Snyder, James P., Hepler, John R., Yepes, Manuel, Low, Chian-Ming, Traynelis, Stephen F.

“…Zinc is hypothesized to be co-released with glutamate at synapses of the central nervous system. Zinc binds to NR1/NR2A N-methyl-d-aspartate (NMDA) receptors…”
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An Atypical Case of Bartonella henselae Osteomyelitis and Hepatic Disease by Boston, Catherine, McMahon, Pamela M., Vance, Katie M., Mathews, Dionna M., Bolton, Michael T.

“…Bartonella henselae is a Gram-negative bacterium and the causative agent of cat scratch disease (CSD). Atypical presentations of B. henselae that involve the…”
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PAR1-activated astrocytes in the nucleus of the solitary tract stimulate adjacent neurons via NMDA receptors by Vance, Katie M, Rogers, Richard C, Hermann, Gerlinda E

“…Severe autonomic dysfunction, including the loss of control of the cardiovascular, respiratory, and gastrointestinal systems, is a common comorbidity of stroke…”
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Predicting severe COVID-19 using readily available admission indicators: SpO2/FiO2 ratio, comorbidity index, and gender by Vu, Luan D., Christofferson, Rebecca C., O’Neal, Hollis R., Hamer, Diana, Phan, Anh T. Q., Vance, Katie M., Turner, E. A., Kumar, Avinash, Yola, Ibrahim Musa, Lim, Natalie, Ogden, Beverly, Cormier, Stephania A.

“…The focus of this study was to identify risk factors for severe and critical COVID-19, evaluate local respiratory immune responses to SARS-CoV-2 infection, and…”
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A structurally derived model of subunit‐dependent NMDA receptor function by Gibb, Alasdair J., Ogden, Kevin K., McDaniel, Miranda J., Vance, Katie M., Kell, Steven A., Butch, Chris, Burger, Pieter, Liotta, Dennis C., Traynelis, Stephen F.

“…Key points The kinetics of NMDA receptor (NMDAR) signalling are a critical aspect of the physiology of excitatory synaptic transmission in the brain. Here we…”
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GluN1 splice variant control of GluN1/GluN2D NMDA receptors by Vance, Katie M., Hansen, Kasper B., Traynelis, Stephen F.

“…Key points •  NMDA receptors are ionotropic glutamate receptors that mediate the slow component of excitatory synaptic transmission in the central nervous…”
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Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors by Hansen, Kasper B, Tajima, Nami, Risgaard, Rune, Perszyk, Riley E, Jørgensen, Lars, Vance, Katie M, Ogden, Kevin K, Clausen, Rasmus P, Furukawa, Hiro, Traynelis, Stephen F

“…N-methyl-d-aspartate (NMDA) receptors are ligand-gated ion channels assembled from GluN1 and GluN2 subunits. We used a series of N-hydroxypyrazole-5-glycine…”
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Structure–Activity Relationships and Pharmacophore Model of a Noncompetitive Pyrazoline Containing Class of GluN2C/GluN2D Selective Antagonists by Acker, Timothy M, Khatri, Alpa, Vance, Katie M, Slabber, Cathryn, Bacsa, John, Snyder, James P, Traynelis, Stephen F, Liotta, Dennis C

“…Here we describe the synthesis and structure–activity relationship for a class of pyrazoline-containing dihydroquinolone negative allosteric modulators of the…”
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NMDA receptors control vagal afferent excitability in the nucleus of the solitary tract by Vance, Katie M, Rogers, Richard C, Hermann, Gerlinda E

“…Abstract Previous behavioral studies have demonstrated that presynaptic N-methyl- d -aspartate (NMDA) receptors expressed on vagal afferent terminals are…”
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A Novel Negative Allosteric Modulator Selective for GluN2C/2D-Containing NMDA Receptors Inhibits Synaptic Transmission in Hippocampal Interneurons by Swanger, Sharon A, Vance, Katie M, Acker, Timothy M, Zimmerman, Sommer S, DiRaddo, John O, Myers, Scott J, Bundgaard, Christoffer, Mosley, Cara A, Summer, Samantha L, Menaldino, David S, Jensen, Henrik S, Liotta, Dennis C, Traynelis, Stephen F

“…N-Methyl-d-aspartate receptors (NMDARs) are ionotropic glutamate receptors that mediate excitatory synaptic transmission and have been implicated in numerous…”
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Modal gating of GluN1/GluN2D NMDA receptors by Vance, Katie M., Hansen, Kasper B., Traynelis, Stephen F.

“…GluN2D-containing NMDA receptors are characterized by an unusually low open probability (0.023), even in the presence of saturating glutamate and glycine…”
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Artemisia santolinifolia enhances glutamatergic neurotransmission in the nucleus of the solitary tract by Vance, Katie M., Ribnicky, David M., Rogers, Richard C., Hermann, Gerlinda E.

“…•We evaluated how three Artemisia species modulate the vagal afferent-NST synapse.•A. santolinifolia increased calcium levels in prelabeled vagal afferent…”
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