Search Results - "Vanacker, Hélène"

Adenylates regulate Arabidopsis plastidial thioredoxin activities through the binding of a CBS domain protein by Baudry, Kevin, Barbut, Félix, Domenichini, Séverine, Guillaumot, Damien, Thy, Mai Pham, Vanacker, Hélène, Majeran, Wojciech, Krieger-Liszkay, Anja, Issakidis-Bourguet, Emmanuelle, Lurin, Claire

“…Cystathionine-β-synthase (CBS) domains are found in proteins of all living organisms and have been proposed to play a role as energy sensors regulating protein…”
Get full text

Interactions between biosynthesis, compartmentation and transport in the control of glutathione homeostasis and signalling by Noctor, Graham, Gomez, Leonardo, Vanacker, Hélène, Foyer, Christine H.

“…Glutathione has numerous roles in cellular defence and in sulphur metabolism. These functions depend or impact on the concentration and/or redox state of leaf…”
Get full text

S‐Nitrosylation of the histone deacetylase HDA19 stimulates its activity to enhance plant stress tolerance in Arabidopsis by Zheng, Yu, Li, Zhenting, Cui, Xiaoyun, Yang, Zheng, Bao, Chun, Pan, Lei, Liu, Xiaoyun, Chatel‐Innocenti, Gilles, Vanacker, Hélène, Noctor, Graham, Dard, Avilien, Reichheld, Jean‐Philippe, Issakidis‐Bourguet, Emmanuelle, Zhou, Dao‐Xiu

“…SUMMARY Arabidopsis histone deacetylase HDA19 is required for gene expression programs of a large spectrum of plant developmental and stress‐responsive…”
Get full text

Conditional oxidative stress responses in the Arabidopsis photorespiratory mutant cat2 demonstrate that redox state is a key modulator of daylength-dependent gene expression, and define photoperiod as a crucial factor in the regulation of H₂O₂-induced cell death by Queval, Guillaume, Issakidis-Bourguet, Emmanuelle, Hoeberichts, Frank A, Vandorpe, Michaël, Gakière, Bertrand, Vanacker, Hélène, Miginiac-Maslow, Myroslawa, Van Breusegem, Frank, Noctor, Graham

“…Photorespiration is a light-dependent source of H₂O₂ in the peroxisomes, where concentrations of this signalling molecule are regulated by catalase. Growth of…”
Get full text

Thioredoxins m regulate plastid glucose-6-phosphate dehydrogenase activity in Arabidopsis roots under salt stress by Née, Guillaume, Wang, Fuzheng, Châtel-Innocenti, Gilles, Mhamdi, Amna, Juranville, Eugénie, Vanacker, Hélène, Noctor, Graham, Issakidis-Bourguet, Emmanuelle

“…Plants contain several NADPH-producing enzymes including glucose-6-phosphate dehydrogenases (G6PDH) with different sub-cellular localizations. The activity of…”
Get full text

Glutathione oxidation in response to intracellular H2O2: Key but overlapping roles for dehydroascorbate reductases by Rahantaniaina, Marie-Sylviane, Li, Shengchun, Chatel-Innocenti, Gilles, Tuzet, Andrée, Mhamdi, Amna, Vanacker, Hélène, Noctor, Graham

“…Glutathione is a pivotal molecule in oxidative stress, during which it is potentially oxidized by several pathways linked to H 2 O 2 detoxification. We have…”
Get full text

Xevinapant Combined with Pembrolizumab in Patients with Advanced, Pretreated, Colorectal and Pancreatic Cancer: Results of the Phase Ib/II CATRIPCA Trial by Voisin, Allison, Terret, Catherine, Schiffler, Camille, Bidaux, Anne-Sophie, Vanacker, Hélène, Perrin-Niquet, Marlène, Barbery, Maud, Vinceneux, Armelle, Eberst, Lauriane, Stéphan, Pierre, Garin, Gwenaële, Spaggiari, Dany, Pérol, David, Grinberg-Bleyer, Yenkel, Cassier, Philippe A

“…Xevinapant is an orally available inhibitor of apoptosis proteins (IAP) inhibitor. Preclinical data suggest that IAP antagonism may synergize with immune…”
Get full text

Redox Regulation of Monodehydroascorbate Reductase by Thioredoxin y in Plastids Revealed in the Context of Water Stress by Vanacker, Hélène, Guichard, Marjorie, Bohrer, Anne-Sophie, Issakidis-Bourguet, Emmanuelle

“…Thioredoxins (TRXs) are key players within the complex response network of plants to environmental constraints. Here, the physiological implication of the…”
Get full text

p4EBP1 staining predicts outcome in ER-positive endocrine-resistant metastatic breast cancer patients treated with everolimus and exemestane by Vanacker, Hélène, Treilleux, Isabelle, Schiffler, Camille, Bieche, Ivan, Campone, Mario, Patsouris, Anne, Arnedos, Monica, Cottu, Paul H., Jacquin, Jean-Philippe, Dalenc, Florence, Pinton, Antoine, Servant, Nicolas, Attignon, Valéry, Rouleau, Etienne, Morel, Alain, Legrand, François, Jimenez, Marta, Andre, Fabrice, Bachelot, Thomas

“…Background To identify patients most likely to respond to everolimus, a mammalian target of rapamycin (mTOR) inhibitor, a prospective biomarker study was…”
Get full text

Qualitative evaluation of motives for acceptance or refusal of early palliative care in patients included in early-phase clinical trials in a French comprehensive cancer center: the PALPHA study by Lochmann, Mathilde, Girodet, Magali, Despax, Johanna, Baudry, Valentine, Duranti, Julie, Mastroianni, Bénédicte, Vanacker, Hélène, Vinceneux, Armelle, Brahmi, Mehdi, Renard, Olivier, Verlingue, Loïc, Amini-Adle, Mona, Swalduz, Aurélie, Gautier, Julien, Ducimetière, Françoise, Anota, Amélie, Cassier, Philippe A., Chvetzoff, Gisèle, Christophe, Véronique

“…Purpose The integration of palliative care (PC) into oncological management is recommended well before the end of life. It improves quality of life and symptom…”
Get full text

Overcoming resistance to PARP inhibitor in epithelial ovarian cancer, are we ready? by Ray-Coquard, Isabelle, Vanacker, Hélène, Le Saux, Olivia, Tredan, Olivier

Get full text

Transcription Factor ABI4 Is Required for the Ascorbic Acid–Dependent Regulation of Growth and Regulation of Jasmonate-Dependent Defense Signaling Pathways in Arabidopsis by Kerchev, Pavel I, Pellny, Till K, Vivancos, Pedro Diaz, Kiddle, Guy, Hedden, Peter, Driscoll, Simon, Vanacker, Hélène, Verrier, Paul, Hancock, Robert D, Foyer, Christine H

“…Cellular redox homeostasis is a hub for signal integration. Interactions between redox metabolism and the ABSCISIC ACID-INSENSITIVE-4 (ABI4) transcription…”
Get full text

Impact of surgery and chemotherapy in ovarian sex cord-stromal tumors from the multicentric Salomé study including 469 patients. A TMRG and GINECO group study by Hanvic, Brunhilde, Lecuru, Fabrice, Vanacker, Hélène, Pautier, Patricia, Narducci, Fabrice, Cherifi, François, Floquet, Anne, Angeles, Martina Aida, Berton, Dominique, Pomel, Christophe, Kalbacher, Elsa, Provansal, Magali, Fernandez, Yolanda, Rouge, Thibault De La Motte, Roméo, Clémence, Laas, Enora, Morice, Philippe, Hudry, Delphine, Meriaux, Emeline, Guyon, Frédéric, Illac-Vauquelin, Claire, Selle, Frédéric, Meeus, Pierre, Genestie, Catherine, Salleron, Julia, Ray-Coquard, Isabelle

“…Identifying prognostic factors and evaluating the impact of adjuvant chemotherapy in patients with sex cord stromal tumors (SCST) is crucial. In this study, we…”
Get full text

Molecular Classification of Endometrial Stromal Sarcomas Using RNA Sequencing Defines Nosological and Prognostic Subgroups with Different Natural History by Brahmi, Mehdi, Franceschi, Tatiana, Treilleux, Isabelle, Pissaloux, Daniel, Ray-Coquard, Isabelle, Dufresne, Armelle, Vanacker, Helene, Carbonnaux, Melodie, Meeus, Pierre, Sunyach, Marie-Pierre, Bouhamama, Amine, Karanian, Marie, Meurgey, Alexandra, Blay, Jean-Yves, Tirode, Franck

“…A series of 42 patient tumors diagnosed as endometrial stromal sarcoma (ESS) based on the morphology but negative for JAZF1 and/or YWHAE rearrangement in FISH…”
Get full text

Reasons for acceptance and refusal of early palliative care in patients included in early-phase clinical trials in a regional comprehensive cancer centre in France: protocol for a qualitative study by Chvetzoff, Gisele, Girodet, Magali, Despax, Johanna, Baudry, Valentine, Duranti, Julie, Mastroianni, Bénédicte, Vanacker, Hélène, Vinceneux, Armelle, Brahmi, Mehdi, Renard, Olivier, Gautier, Julien, Britel, Manon, Ducimetière, Françoise, Anota, Amélie, Cassier, Philippe, Christophe, Véronique

“…IntroductionA few studies have highlighted the potential synergy between early palliative care and inclusion in an early-phase clinical trial that may improve…”
Get full text

H2O2-Activated Up-Regulation of Glutathione in Arabidopsis Involves Induction of Genes Encoding Enzymes Involved in Cysteine Synthesis in the Chloroplast by Queval, Guillaume, Thominet, Dorothée, Vanacker, Hélène, Miginiac-Maslow, Myroslawa, Gakière, Bertrand, Noctor, Graham

“…Glutathione is a key player in cellular redox homeostasis and, therefore, in the response to H2O2, but the factors regulating oxidation-activated glutathione…”
Get full text

Therapeutic relevance of molecular screening program in patients with metastatic sarcoma: Analysis from the ProfiLER 01 trial by Arnaud-Coffin, Patrick, Brahmi, Mehdi, Vanacker, Hélène, Eberst, Lauriane, Tredan, Olivier, Attignon, Valery, Pissaloux, Daniel, Sohier, Emilie, Cassier, Philippe, Garin, Gwenaelle, Pérol, David, Blay, Jean-Yves, Dufresne, Armelle

“…Advanced sarcoma is a group of heterogeneous disease with poor prognosis and poor efficacy of medical treatment. They represent a promising group of tumors to…”
Get full text

Poly(ADP-ribose) polymerase inhibitors in combination with anti-angiogenic agents for the treatment of advanced ovarian cancer by Le Saux, Olivia, Vanacker, Hélène, Guermazi, Fatma, Carbonnaux, Mélodie, Roméo, Clémence, Larrouquère, Louis, Trédan, Olivier, Ray-Coquard, Isabelle

“…Homologous recombination deficiency and VEGF expression are key pathways in high-grade ovarian cancer. Recently, three randomized practice changing trials were…”
Get full text

Oncology research congress: The essentials of the fifth International Symposium 2022 of the Cancer Research Center of Lyon by Albaret, Marie Alexandra, Aïmontché, Eliezer, Bendriss-Vermare, Nathalie, Diaz, Jean-Jacques, Gil, Clara, Hedjam, Jordan, Ichim, Gabriel, Morin, Chloé, Mourksi, Nour-El-Houda, Nguyen, Trang Thi Minh, Picant, Valentin, Picard, Emilie, Popgeorgiev, Nikolay, Tirode, Franck, Vanacker, Hélène, Puisieux, Alain, Mehlen, Patrick

Get more information

ESR1 Rearrangement as a Diagnostic and Predictive Biomarker in Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Report of Four Cases by Bini, Marta, Gantzer, Justine, Dufresne, Armelle, Vanacker, Hélène, Romeo, Clémence, Franceschi, Tatiana, Treilleux, Isabelle, Pissaloux, Daniel, Tirode, Franck, Blay, Jean-Yves, Ray-Coquard, Isabelle, Brahmi, Mehdi

Get more information