Search Results - "VanSteenhouse, Harper C."
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A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling
Published in PloS one (25-05-2017)“…The use of gene expression signatures to classify compounds, identify efficacy or toxicity, and differentiate close analogs relies on the sensitivity of the…”
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Journal Article -
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Extraction-free whole transcriptome gene expression analysis of FFPE sections and histology-directed subareas of tissue
Published in PloS one (22-02-2019)“…We describe the use of a ligation-based targeted whole transcriptome expression profiling assay, TempO-Seq, to profile formalin-fixed paraffin-embedded (FFPE)…”
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Journal Article -
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Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq
Published in Archives of toxicology (01-08-2018)“…The utilisation of genome-wide transcriptomics has played a pivotal role in advancing the field of toxicology, allowing the mapping of transcriptional…”
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Journal Article -
4
T-cadherin structures reveal a novel adhesive binding mechanism
Published in Nature structural & molecular biology (01-03-2010)“…T-cadherin is a non-classical GPI-anchored cadherin. The crystal structures of T-cadherins from different organisms now reveal that the EC1-EC2 regions can…”
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Journal Article -
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Phylogenetic conservation of the cell-type-specific Lan3-2 glycoepitope in Caenorhabditis elegans
Published in Development genes and evolution (01-09-2010)“…The biological function of a cell-type-specific glycosylation of an adhesion molecule belonging to the L1CAM immunoglobulin superfamily was previously…”
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Journal Article -
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Intercellular adhesion and pathfinding molecule T-cadherin in the development of the nervous system
Published 01-01-2007“…Adult animals exhibit an amazing array of behaviors controlled by an exquisitely complex nervous system. Axon pathfinding is an essential component to the…”
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Dissertation