Search Results - "VanMeter, Amy"

A Portrait of Tissue Phosphoprotein Stability in the Clinical Tissue Procurement Process by Espina, Virginia, Edmiston, Kirsten H., Heiby, Michael, Pierobon, Mariaelena, Sciro, Manuela, Merritt, Barbara, Banks, Stacey, Deng, Jianghong, VanMeter, Amy J., Geho, David H., Pastore, Lucia, Sennesh, Joel, Petricoin, Emanuel F., Liotta, Lance A.

“…Little is known about the preanalytical fluctuations of phosphoproteins during tissue procurement for molecular profiling. This information is crucial to…”
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Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type by VanMeter, Amy J, Rodriguez, Adrianna S, Bowman, Elise D, Jen, Jin, Harris, Curtis C, Deng, Jianghong, Calvert, Valerie S, Silvestri, Alessandra, Fredolini, Claudia, Chandhoke, Vikas, Petricoin, 3rd, Emanuel F, Liotta, Lance A, Espina, Virginia

“…Little is known about lung carcinoma epidermal growth factor (EGF) kinase pathway signaling within the context of the tissue microenvironment. We…”
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An Initial Characterization of the Serum Phosphoproteome by Zhou, Weidong, Ross, Mark M, Tessitore, Alessandra, Ornstein, David, VanMeter, Amy, Liotta, Lance A, Petricoin, Emanuel F

“…Phosphorylation is a dynamic post-translational protein modification that is the basis of a general mechanism for maintaining and regulating protein structure…”
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A genomic and proteomic study of the spectrum of nonalcoholic fatty liver disease by YOUNOSSI, Zobair M, BARANOVA, Ancha, ONG, Janus P, GOODMAN, Zachary, CHANDHOKE, Vikas, ZIEGLER, Katharine, DEL GIACCO, Luca, SCHLAUCH, Karen, BORN, Timothy L, ELARINY, Hazem, GORRETA, Francesco, VANMETER, Amy, YOUNOSZAI, Abraham

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and some of its forms are progressive. This study describes the profiling of…”
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Functional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL by Accordi, Benedetta, Espina, Virginia, Giordan, Marco, VanMeter, Amy, Milani, Gloria, Galla, Luisa, Ruzzene, Maria, Sciro, Manuela, Trentin, Luca, De Maria, Ruggero, te Kronnie, Geertruy, Petricoin, Emanuel, Liotta, Lance, Basso, Giuseppe

“…In spite of leukemia therapy improvements obtained over the last decades, therapy is not yet effective in all cases. Current approaches in Acute Lymphoblastic…”
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Phosphoproteomic Analysis of Signaling Pathways in Head and Neck Squamous Cell Carcinoma Patient Samples by Frederick, Mitchell J, VanMeter, Amy J, Gadhikar, Mayur A, Henderson, Ying C, Yao, Hui, Pickering, Curtis C, Williams, Michelle D, El-Naggar, Adel K, Sandulache, Vlad, Tarco, Emily, Myers, Jeffrey N, Clayman, Gary L, Liotta, Lance A, Petricoin, Emanuel F, Calvert, Valerie S, Fodale, Valentina, Wang, Jing, Weber, Randal S

“…Molecular targeted therapy represents a promising new strategy for treating cancers because many small-molecule inhibitors targeting protein kinases have…”
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Identification of thioredoxin reductase 1-regulated genes using small interference RNA and cDNA microarray by Gorreta, Francesco, Runfola, Timothy P., VanMeter, Amy J., Barzaghi, Dagania, Chandhoke, Vikas, Del Giacco, Luca

“…Thioredoxin reductase 1 (TrxR1) is a cytosolic enzyme that plays a central role in controlling cellular redox homeostasis. TrxR1 can transduce regulatory redox…”
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Reverse-phase protein microarrays by Pierobon, Mariaelena, Vanmeter, Amy J, Moroni, Noemi, Galdi, Francesca, Petricoin, 3rd, Emanuel F

“…Cancer is the consequence of intra- and extracellular signaling network deregulation that derives from alteration of genetic and proteomic cellular…”
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Development of a new reference standard for microarray experiments by Gorreta, Francesco, Barzaghi, Dagania, VanMeter, Amy J, Chandhoke, Vikas, Del Giacco, Luca

“…Often microarray studies require a reference to indirectly compare the samples under observation. References based on pooled RNA from different cell lines have…”
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Serum low-molecular-weight protein fractionation for biomarker discovery by VanMeter, Amy J, Camerini, Serena, Polci, Maria Letizia, Tessitore, Alessandra, Trivedi, Nishant, Heiby, Michael, Kamal, Yasmin, Hansen, Jonathan, Zhou, Weidong

“…Protein biomarkers provide the key diagnostic information for the detection of disease, risk of disease progression, and a patient's likely response to drug…”
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Laser Capture Microdissection and Protein Microarray Analysis of Human Non-small Cell Lung Cancer by VanMeter, Amy J., Rodriguez, Adrianna S., Bowman, Elise D., Jen, Jin, Harris, Curtis C., Deng, Jianghong, Calvert, Valerie S., Silvestri, Alessandra, Fredolini, Claudia, Chandhoke, Vikas, Petricoin, Emanuel F., Liotta, Lance A., Espina, Virginia

“…Little is known about lung carcinoma epidermal growth factor (EGF) kinase pathway signaling within the context of the tissue microenvironment. We…”
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Laser-capture microdissection by Liotta, Lance A, Espina, Virginia, Wulfkuhle, Julia D, Calvert, Valerie S, VanMeter, Amy, Zhou, Weidong, Coukos, George, Geho, David H, Petricoin, Emanuel F

“…Deciphering the cellular and molecular interactions that drive disease within the tissue microenvironment holds promise for discovering drug targets of the…”
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Reverse Phase Protein Microarrays by Baldelli, Elisa, Calvert, Valerie, Hodge, Alex, VanMeter, Amy, Petricoin, 3rd, Emanuel F, Pierobon, Mariaelena

“…While genes and RNA encode information about cellular status, proteins are considered the engine of the cellular machine, as they are the effective elements…”
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The heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimer's disease by Mueller, Claudius, Zhou, Weidong, Vanmeter, Amy, Heiby, Michael, Magaki, Shino, Ross, Mark M, Espina, Virginia, Schrag, Matthew, Dickson, Cindy, Liotta, Lance A, Kirsch, Wolff M

“…One of the remaining challenges in Alzheimer's disease (AD) research is the establishment of biomarkers for early disease detection. As part of a prospective…”
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Reverse-phase protein microarrays: application to biomarker discovery and translational medicine by VanMeter, Amy, Signore, Michele, Pierobon, Mariaelena, Espina, Virginia, Liotta, Lance A, Petricoin, 3rd, Emanuel F

“…Mapping of protein signaling networks within tumors can identify new targets for therapy and provide a means to stratify patients for individualized therapy…”
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Abstract 1265: Tissue is alive: Preserving phosphoproteins and tissue morphology in clinical trial samples by Mueller, Claudius, Colarossi, Lorenzo, Chiechi, Antonella, Gallagher, Rosa I., VanMeter, Amy, Edmiston, Kirsten H., Holmes, Frankie A., Nagarwala, Yasir, Liotta, Lance A., Espina, Virginia A.

“…Abstract An urgent clinical goal is to identify subpopulations of cancer patients that may respond to targeted kinase inhibitors and/or their phosphorylated…”
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Abstract 1542: CD38 is physically associated with CD49d and enhances CD49d-mediated adhesion of B-Cell chronic lymphocytic leukemia cells by Benedetti, Dania, Zucchetto, Antonella, Vaisitti, Tiziana, Del Poeta, Giovanni, VanMeter, Amy, Espina, Virginia, Malavasi, Fabio, Deaglio, Silvia, Gattei, Valter

“…Abstract CD49d, a recently identified negative prognosticator in chronic lymphocytic leukemia (CLL), is an adhesion molecule mediating microenvironmental…”
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Circulating CLL Cells Expressing CD49d Display a Phospho-Proteomic Profile Consistent with a Constitutive Receptor Engagement by Blood-Borne Ligands by Benedetti, Dania, Tissino, Erika, Marconi, Daniela, Bo, Michele Dal, Bomben, Riccardo, Vaisitti, Tiziana, Deaglio, Silvia, Rossi, Davide, Gaidano, Gianluca, Pozzato, Gabriele, Raimondo, Francesco Di, Del Poeta, Giovanni, VanMeter, Amy, Zucchetto, Antonella, Espina, Virginia, Liotta, Lance, Gattei, Valter

“…Abstract 930 Chronic lymphocytic leukemia (CLL) cell growth and survival occur in defined microenvironment niches controlled by several receptor/ligand…”
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Hepatic gene expression in patients with obesity-related non-alcoholic steatohepatitis by Younossi, Zobair M., Gorreta, Francesco, Ong, Janus P., Schlauch, Karen, Del Giacco, Luca, Elariny, Hazem, Van Meter, Amy, Younoszai, Abraham, Goodman, Zachary, Baranova, Anna, Christensen, Alan, Grant, Geraldine, Chandhoke, Vikas

“…: Background: Non‐alcoholic fatty liver disease (NAFLD) is among the most common causes of chronic liver disease. NAFLD includes a spectrum of…”
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Ex Vivo Multiplexed Signal Pathway Inhibitor Treatment Reveals Differential Sensitivity of Myeloma and Non-Myeloma Bone Marrow Cell Populations by Espina, Virginia, Romano, Alessandra, VanMeter, Amy, Orloff, Gregory, Spira, Alexander I., Patel, Dipti, Walker, Christopher, Petricoin, Emanuel F, Liotta, Lance A

“…Abstract 2860 Poster Board II-836 Multiple Myeloma (MM) is a heterogeneous disease, and despite significant advances in therapy it remains incurable. A major…”
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