Search Results - "Van haften, Floortje J"
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Chemically engineered glycan-modified cancer vaccines to mobilize skin dendritic cells
Published in Current opinion in chemical biology (01-12-2019)“…Dendritic cell (DC)–targeting vaccines show great promise in increasing antitumor immunity. Glycan-engineered vaccines facilitate both DC targeting and…”
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Delayed vaccine-induced CD8+ T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication
Published in Journal for immunotherapy of cancer (29-11-2023)“…BackgroundThe survival of patients with cervical cancer who are treated with cisplatin in conjunction with the topoisomerase I inhibitor topotecan is enhanced…”
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3
OX40 agonism enhances PD-L1 checkpoint blockade by shifting the cytotoxic T cell differentiation spectrum
Published in Cell reports. Medicine (21-03-2023)“…Immune checkpoint therapy (ICT) has the power to eradicate cancer, but the mechanisms that determine effective therapy-induced immune responses are not fully…”
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Memory CD8+ T cell heterogeneity is primarily driven by pathogen-specific cues and additionally shaped by the tissue environment
Published in iScience (22-01-2021)“…Factors that govern the complex formation of memory T cells are not completely understood. A better understanding of the development of memory T cell…”
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Inhibiting the NADase CD38 improves cytomegalovirus-specific CD8+ T cell functionality and metabolism
Published in The Journal of clinical investigation (02-07-2024)“…Cytomegalovirus (CMV) is one of the most common and relevant opportunistic pathogens in immunocompromised individuals such as kidney transplant recipients…”
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Inhibiting the NADase CD38 improves cytomegalovirus-specific [CD8.sup.+] T cell functionality and metabolism
Published in The Journal of clinical investigation (01-09-2024)“…Cytomegalovirus (CMV) is one of the most common and relevant opportunistic pathogens in people who are immunocompromised, such as kidney transplant recipients…”
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Journal Article -
7
Inhibiting the NADase CD38 improves cytomegalovirus-specific CD8+ T cell functionality and metabolism
Published in The Journal of clinical investigation (01-09-2024)“…Cytomegalovirus (CMV) is one of the most common and relevant opportunistic pathogens in people who are immunocompromised, such as kidney transplant recipients…”
Get full text
Journal Article