Search Results - "Van der Zee, Catharina E E M"
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Mixed‐methods exploration of students' motivation in using augmented reality in neuroanatomy education with prosected specimens
Published in Anatomical sciences education (01-08-2022)“…The use of augmented reality (AR) in teaching and studying neuroanatomy has been well researched. Previous research showed that AR‐based learning of…”
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Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice
Published in Journal of neurochemistry (01-05-2007)“…The neuronal protein tyrosine phosphatases encoded by mouse gene Ptprr (PTPBR7, PTP‐SL, PTPPBSγ‐42 and PTPPBSγ‐37) have been implicated in mitogen‐activated…”
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Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice
Published in Behavioural brain research (17-03-2010)“…The 9q34.3 subtelomeric deletion syndrome is a newly defined mental retardation syndrome, caused by haplo-insufficiency of the euchromatin histone…”
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Actual drawing of histological images improves knowledge retention
Published in Anatomical sciences education (01-01-2016)“…Medical students have to process a large amount of information during the first years of their study, which has to be retained over long periods of nonuse…”
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Protein tyrosine phosphatase receptor type R deficient mice exhibit increased exploration in a new environment and impaired novel object recognition memory
Published in Behavioural brain research (15-05-2014)“…•PTPRR isoforms are expressed throughout the mouse brain.•Ptprr knockout mice display normal olfactory bulb-related basal smell function.•In Ptprr knockout…”
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Mild impairment of motor nerve repair in mice lacking PTP-BL tyrosine phosphatase activity
Published in Physiological genomics (16-09-2004)“…1 Department of Cell Biology, Nijmegen Center for Molecular Life Sciences, University Medical Center Nijmegen, 6525 GA Nijmegen, The Netherlands 2 Department…”
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Conditional Deletion of the Itgb4 Integrin Gene in Schwann Cells Leads to Delayed Peripheral Nerve Regeneration
Published in The Journal of neuroscience (29-10-2008)“…Several different integrins participate in the complex interactions that promote repair of the peripheral nervous system. The role of the integrin alpha6beta4…”
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8
lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells
Published in Journal of molecular histology (01-02-2010)“…Endocytosis, subsequent protein sorting into multivesicular bodies (MVBs), and eventual degradation in lysosomes compose an important mechanism for controlling…”
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Mice lacking brain-type creatine kinase activity show defective thermoregulation
Published in Physiology & behavior (20-04-2009)“…Abstract The cytosolic brain-type creatine kinase and mitochondrial ubiquitous creatine kinase (CK-B and UbCKmit) are expressed during the prepubescent and…”
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Complete brain‐type creatine kinase deficiency in mice blocks seizure activity and affects intracellular calcium kinetics
Published in Epilepsia (Copenhagen) (01-01-2010)“…Summary Purpose: Brain‐type creatine kinase (CK‐B) and ubiquitous mitochondrial creatine kinase (UbCKmit) act as components of local phosphocreatine ATP…”
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Reduced Euchromatin histone methyltransferase 1 causes developmental delay, hypotonia, and cranial abnormalities associated with increased bone gene expression in Kleefstra syndrome mice
Published in Developmental biology (15-02-2014)“…Haploinsufficiency of Euchromatin histone methyltransferase 1 (EHMT1), a chromatin modifying enzyme, is the cause of Kleefstra syndrome (KS). KS is an…”
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Nerve Growth Factor Accelerates Seizure Development, Enhances Mossy Fiber Sprouting, and Attenuates Seizure-Induced Decreases in Neuronal Density in the Kindling Model of Epilepsy
Published in The Journal of neuroscience (15-07-1997)“…Recurrent seizure activity induced during kindling has been reported to produce a functional synaptic reorganization of the mossy fibers in the hippocampus. To…”
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13
Flow of energy in the outer retina in darkness and in light
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-2010)“…Structural features of neurons create challenges for effective production and distribution of essential metabolic energy. We investigated how metabolic energy…”
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Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation
Published in Scientific reports (10-01-2017)“…Heterozygous mutations or deletions of the human Euchromatin Histone Methyltransferase 1 ( EHMT1 ) gene are the main causes of Kleefstra syndrome, a…”
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Hair Bundles Are Specialized for ATP Delivery via Creatine Kinase
Published in Neuron (Cambridge, Mass.) (01-02-2007)“…When stimulated strongly, a hair cell's mechanically sensitive hair bundle may consume ATP too rapidly for replenishment by diffusion. To provide a broad view…”
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Hypothalamic plasticity of neuropeptide Y is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation
Published in European journal of pharmacology (05-11-2013)“…The neural substrate of adaptive thermoregulation in mice lacking both brain-type creatine kinase isoforms is further investigated. The cytosolic brain-type…”
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Enoxaparin treatment administered at both early and late stages of amyloid β deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain Aβ levels
Published in Neurobiology of disease (01-10-2010)“…Abstract Enoxaparin (Enox), a low molecular weight heparin, has been shown to lower brain amyloid β (Aβ) load in a mouse model for Alzheimer's disease…”
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Structural and behavioural consequences of double deficiency for creatine kinases BCK and UbCKmit
Published in Behavioural brain research (28-02-2005)“…The cytosolic brain-type creatine kinase (BCK) isoform and the mitochondrial ubiquitous creatine kinase (UbCKmit) isoform are both important for the…”
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Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility
Published in The European journal of neuroscience (01-05-2002)“…Creatine kinases are important in maintaining cellular‐energy homeostasis, and neuroprotective effects have been attributed to the administration of creatine…”
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Effects of LAR and PTP-BL phosphatase deficiency on adult mouse retinal cells activated by lens injury
Published in The European journal of neuroscience (01-05-2005)“…Using intact and lens‐lesioned wildtype, leucocyte common antigen‐related phosphatase deficient (LARΔP) and protein tyrosine phosphatase (PTP)‐BAS‐like…”
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