Search Results - "Van der Worp, H"

Increasing value and reducing waste: addressing inaccessible research by Chan, An-Wen, Dr, Song, Fujian, Prof, Vickers, Andrew, PhD, Jefferson, Tom, MD, Dickersin, Kay, Prof, Gøtzsche, Peter C, Prof, Krumholz, Harlan M, Prof, Ghersi, Davina, PhD, van der Worp, H Bart, PhD

“…Summary The methods and results of health research are documented in study protocols, full study reports (detailing all analyses), journal reports, and…”
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Long-term outcomes after stenting versus endarterectomy for treatment of symptomatic carotid stenosis: the International Carotid Stenting Study (ICSS) randomised trial by Bonati, Leo H, MD, Dobson, Joanna, MSc, Featherstone, Roland L, PhD, Ederle, Jörg, PhD, van der Worp, H Bart, PhD, de Borst, Gert J, PhD, Mali, Willem P Th M, Prof, Beard, Jonathan D, ChM, Cleveland, Trevor, FRCR, Engelter, Stefan T, MD, Lyrer, Philippe A, MD, Ford, Gary A, Prof, Dorman, Paul J, FRCP, Brown, Martin M, Prof

“…Summary Background Stenting is an alternative to endarterectomy for treatment of carotid artery stenosis, but long-term efficacy is uncertain. We report…”
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Can animal models of disease reliably inform human studies? by van der Worp, H Bart, Howells, David W, Sena, Emily S, Porritt, Michelle J, Rewell, Sarah, O'Collins, Victoria, Macleod, Malcolm R

“…H. Bart van der Worp and colleagues discuss the controversies and possibilities of translating the results of animal experiments into human clinical trials…”
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Posterior circulation ischaemic stroke and transient ischaemic attack: diagnosis, investigation, and secondary prevention by Markus, Hugh S, Prof, van der Worp, H Bart, MD, Rothwell, Peter M, Prof

“…Summary A fifth of all strokes and transient ischaemic attacks occur in the posterior circulation arterial territory. Diagnosis can be challenging, in part…”
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Publication bias in reports of animal stroke studies leads to major overstatement of efficacy by Sena, Emily S, van der Worp, H Bart, Bath, Philip M W, Howells, David W, Macleod, Malcolm R

“…The consolidation of scientific knowledge proceeds through the interpretation and then distillation of data presented in research reports, first in review…”
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How can we improve the pre-clinical development of drugs for stroke? by Sena, Emily, van der Worp, H. Bart, Howells, David, Macleod, Malcolm

“…The development of stroke drugs has been characterized by success in animal studies and subsequent failure in clinical trials. Animal studies might have…”
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Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials by Vahedi, Katayoun, MD, Hofmeijer, Jeannette, MD, Juettler, Eric, MD, Vicaut, Eric, PhD, George, Bernard, MD, Algra, Ale, MD, Amelink, G Johan, MD, Schmiedeck, Peter, MD, Schwab, Stefan, MD, Rothwell, Peter M, MD, Bousser, Marie-Germaine, MD, van der Worp, H Bart, MD, Hacke, Werner, Prof

“…Summary Background Malignant infarction of the middle cerebral artery (MCA) is associated with an 80% mortality rate. Non-randomised studies have suggested…”
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Hypothermia in animal models of acute ischaemic stroke: a systematic review and meta-analysis by van der Worp, H. Bart, Sena, Emily S., Donnan, Geoffrey A., Howells, David W., Macleod, Malcolm R.

“…Induced hypothermia is proposed as a treatment for acute ischaemic stroke, but there have been too few clinical trials involving too few patients to draw any…”
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Pioglitazone and the secondary prevention of cardiovascular disease. A meta-analysis of randomized-controlled trials by de Jong, Marit, van der Worp, H Bart, van der Graaf, Yolanda, Visseren, Frank L J, Westerink, Jan

“…Pioglitazone targets multiple pathogenic pathways involved in the development of cardiovascular diseases (CVD). The aim of this systematic review and…”
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Ischemic Brain Lesions After Carotid Artery Stenting Increase Future Cerebrovascular Risk by Gensicke, Henrik, MD, van der Worp, H. Bart, PhD, Nederkoorn, Paul J., PhD, Macdonald, Sumaira, PhD, Gaines, Peter A., MBChB, van der Lugt, Aad, MD, Mali, Willem P.Th.M., MD, Lyrer, Philippe A., MD, Peters, Nils, MD, Featherstone, Roland L., PhD, de Borst, Gert J., MD, Engelter, Stefan T., MD, Brown, Martin M., MD, Bonati, Leo H., MD

“…Abstract Background Brain lesions on diffusion-weighted imaging (DWI) are frequently found after carotid artery stenting (CAS), but their clinical relevance…”
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Effect of white-matter lesions on the risk of periprocedural stroke after carotid artery stenting versus endarterectomy in the International Carotid Stenting Study (ICSS): a prespecified analysis of data from a randomised trial by Ederle, Jörg, PhD, Davagnanam, Indran, FRCR, van der Worp, H Bart, PhD, Venables, Graham S, FRCP, Lyrer, Philippe A, MD, Featherstone, Roland L, PhD, Brown, Martin M, Prof, Jäger, H Rolf, FRCR

“…Summary Background Findings from randomised trials have shown a higher early risk of stroke after carotid artery stenting than after carotid endarterectomy. We…”
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Preventive ceftriaxone in patients at high risk of stroke-associated pneumonia. A post-hoc analysis of the PASS trial by Sluis, Wouter M, Westendorp, Willeke F, van de Beek, Diederik, Nederkoorn, Paul J, van der Worp, H Bart

“…Infections complicate the acute phase of stroke in one third of patients and especially pneumonia is associated with increased risk of death or dependency. In…”
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The prognostic value of domain-specific cognitive abilities in acute first-ever stroke by NYS, G. M. S, VAN ZANDVOORT, M. J. E, DE KORT, P. L. M, VAN DER WORP, H. B, JANSEN, B. P. W, ALGRA, A, DE HAAN, E. H. F, KAPPELLE, L. J

“…To evaluate the prognostic value of domain-specific cognitive abilities in acute stroke with respect to long-term cognitive and functional outcome in addition…”
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Increasing value and reducing waste in stroke research by Berge, Eivind, PhD, Salman, Rustam Al-Shahi, Prof, van der Worp, H Bart, PhD, Stapf, Christian, Prof, Sandercock, Peter, Prof, Sprigg, Nikola, DM, Macleod, Malcolm R, Prof, Kelly, Peter J, Prof, Nederkoorn, Paul J, MD, Ford, Gary A, MD

“…Summary Stroke is a major burden to patients and society, and resources spent on stroke research must be used efficiently and produce good value in terms of…”
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Stroke care in Europe during the COVID‐19 pandemic by Aguiar de Sousa, D., Worp, H. B.

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COL4A1 mutation in two preterm siblings with antenatal onset of parenchymal hemorrhage by de Vries, Linda S., Koopman, Corine, Groenendaal, Floris, Van Schooneveld, Mary, Verheijen, Frans W., Verbeek, Elly, Witkamp, Theo D., van der Worp, H. Bart, Mancini, Grazia

“…Objective To report the presence of intracerebral hemorrhage and porencephaly, both present at birth, in two preterm infants with a mutation in the collagen 4…”
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Prospective Study of the Relation between Landing Biomechanics and Jumper's Knee by der Worp, H van, van der Does, H T D, Brink, M S, Zwerver, J, Hijmans, J M

“…The literature on the relation between jump biomechanics and jumper's knee indicates that a jump with horizontal displacement poses a threat for developing…”
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1,026 Experimental treatments in acute stroke by O'Collins, Victoria E., Macleod, Malcolm R., Donnan, Geoffrey A., Horky, Laura L., van der Worp, Bart H., Howells, David W.

“…Objective Preclinical evaluation of neuroprotectants fostered high expectations of clinical efficacy. When not matched, the question arises whether experiments…”
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Surgical decompression for space-occupying cerebral infarction (the Hemicraniectomy After Middle Cerebral Artery infarction with Life-threatening Edema Trial [HAMLET]): a multicentre, open, randomised trial by Hofmeijer, Jeannette, MD, Kappelle, L Jaap, MD, Algra, Ale, MD, Amelink, G Johan, MD, van Gijn, Jan, FRCP, van der Worp, H Bart, MD

“…Summary Background Patients with space-occupying hemispheric infarctions have a poor prognosis, with case fatality rates of up to 80%. In a pooled analysis of…”
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Noninvasive MR imaging of cerebral perfusion in patients with a carotid artery stenosis by BOKKERS, R. P. H, VAN DER WORP, H. B, MALI, W. P. T. M, HENDRIKSE, J

“…Arterial spin labeling (ASL) perfusion MRI with image acquisition at multiple delay times can be used to measure delays in the arrival of arterial blood to the…”
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