Search Results - "Van der Reijden, A"

High-throughput multilocus sequence typing: bringing molecular typing to the next level by Boers, Stefan A, van der Reijden, Wil A, Jansen, Ruud

“…Multilocus sequence typing (MLST) is a widely used system for typing microorganisms by sequence analysis of housekeeping genes. The main advantage of MLST in…”
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Successful Transfer of Umbilical Cord Blood CD34 + Hematopoietic Stem and Progenitor-derived NK Cells in Older Acute Myeloid Leukemia Patients by Dolstra, Harry, Roeven, Mieke W H, Spanholtz, Jan, Hangalapura, Basav N, Tordoir, Marleen, Maas, Frans, Leenders, Marij, Bohme, Fenna, Kok, Nina, Trilsbeek, Carel, Paardekooper, Jos, van der Waart, Anniek B, Westerweel, Peter E, Snijders, Tjeerd J F, Cornelissen, Jan, Bos, Gerard, Pruijt, Hans F M, de Graaf, Aniek O, van der Reijden, Bert A, Jansen, Joop H, van der Meer, Arnold, Huls, Gerwin, Cany, Jeannette, Preijers, Frank, Blijlevens, Nicole M A, Schaap, Nicolaas M

“…Older acute myeloid leukemia (AML) patients have a poor prognosis; therefore, novel therapies are needed. Allogeneic natural killer (NK) cells have been…”
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BCR::ABL1 kinase domain mutation testing and clinical outcome in a nationwide chronic myeloid leukemia patient population by Kockerols, Camille, Valk, Peter J. M., Blijlevens, Nicole M. A., Cornelissen, Jan J., Dinmohamed, Avinash G., Geelen, Inge, Hoogendoorn, Mels, Janssen, Jeroen J. W. M., Daenen, Laura G. M., Reijden, Bert A. van der, Westerweel, Peter E.

“…Abstract Objectives Acquired missense mutations in the BCR::ABL1 kinase domain (KD) may cause tyrosine kinase inhibitor (TKI) treatment failure. Based on…”
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Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data by Sandmann, Sarah, de Graaf, Aniek O., Karimi, Mohsen, van der Reijden, Bert A., Hellström-Lindberg, Eva, Jansen, Joop H., Dugas, Martin

“…Valid variant calling results are crucial for the use of next-generation sequencing in clinical routine. However, there are numerous variant calling tools that…”
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Identification of transcription factors dictating blood cell development using a bidirectional transcription network-based computational framework by Heuts, B. M. H., Arza-Apalategi, S., Frölich, S., Bergevoet, S. M., van den Oever, S. N., van Heeringen, S. J., van der Reijden, B. A., Martens, J. H. A.

“…Advanced computational methods exploit gene expression and epigenetic datasets to predict gene regulatory networks controlled by transcription factors (TFs)…”
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Transcription factor 4 ( TCF4 ) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia by In't Hout, Florentien E M, Gerritsen, Mylène, Bullinger, Lars, Van der Reijden, Bert A, Huls, Gerwin, Vellenga, Edo, Jansen, Joop H

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Inducible MLL-AF9 Expression Drives an AML Program during Human Pluripotent Stem Cell-Derived Hematopoietic Differentiation by Heuts, Branco M H, Arza-Apalategi, Saioa, Alkema, Sinne G, Tijchon, Esther, Jussen, Laura, Bergevoet, Saskia M, van der Reijden, Bert A, Martens, Joost H A

“…A t(9;11)(p22;q23) translocation produces the MLL-AF9 fusion protein, which is found in up to 25% of de novo AML cases in children. Despite major advances,…”
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Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party by Schuurhuis, Gerrit J., Heuser, Michael, Freeman, Sylvie, Béné, Marie-Christine, Buccisano, Francesco, Cloos, Jacqueline, Grimwade, David, Haferlach, Torsten, Hills, Robert K., Hourigan, Christopher S., Jorgensen, Jeffrey L., Kern, Wolfgang, Lacombe, Francis, Maurillo, Luca, Preudhomme, Claude, van der Reijden, Bert A., Thiede, Christian, Venditti, Adriano, Vyas, Paresh, Wood, Brent L., Walter, Roland B., Döhner, Konstanze, Roboz, Gail J., Ossenkoppele, Gert J.

“…Measurable residual disease (MRD; previously termed minimal residual disease) is an independent, postdiagnosis, prognostic indicator in acute myeloid leukemia…”
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Comparison of the Performance of the PanBio COVID-19 Antigen Test in SARS-CoV-2 B.1.1.7 (Alpha) Variants versus non-B.1.1.7 Variants by van Ogtrop, M L, van de Laar, T J W, Eggink, D, Vanhommerig, J W, van der Reijden, W A

“…This study evaluates the performance of the PanBio COVID-19 antigen (Ag) test as part of a hospital infection control policy. Hospital staff was encouraged to…”
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Preferential expression of a high number of ATP binding cassette transporters in both normal and leukemic CD34+CD38− cells by de Grouw, E P L M, Raaijmakers, M H G P, Boezeman, J B, van der Reijden, B A, van de Locht, L T F, de Witte, T J M, Jansen, J H, Raymakers, R A P

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High expression of transcription factor 4 (TCF4) is an independent adverse prognostic factor in acute myeloid leukemia that could guide treatment decisions by in 't Hout, Florentien E M, van der Reijden, Bert A, Monteferrario, Davide, Jansen, Joop H, Huls, Gerwin

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Sex Differences in the Spectrum of Clonal Hematopoiesis by Kamphuis, Priscilla, Zeventer, Isabelle A., Graaf, Aniek O., Salzbrunn, Jonas B., Bergen, Maaike G. J. M., Dinmohamed, Avinash G., Reijden, Bert A., Schuringa, Jan Jacob, Jansen, Joop H., Huls, Gerwin

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The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice by Khandanpour, Cyrus, Krongold, Joseph, Schɒtte, Judith, Bouwman, Frederique, Vassen, Lothar, Gaudreau, Marie-Claude, Chen, Riyan, Calero-Nieto, Fernando J., Diamanti, Evangelia, Hannah, Rebecca, Meyer, Sara E., Grimes, H. Leighton, van der Reijden, Bert A., Jansen, Joop H., Patel, Chandrashekhar V., Peeters, Justine K., Löwenberg, Bob, Dɒhrsen, Ulrich, Göttgens, Bertie, Möröy, Tarik

“…The coding single nucleotide polymorphism GFI136N in the human gene growth factor independence 1 (GFI1) is present in 37-77 of whites and increases the risk…”
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appreci8: a pipeline for precise variant calling integrating 8 tools by Sandmann, Sarah, Karimi, Mohsen, de Graaf, Aniek O, Rohde, Christian, Göllner, Stefanie, Varghese, Julian, Ernsting, Jan, Walldin, Gunilla, van der Reijden, Bert A, Müller-Tidow, Carsten, Malcovati, Luca, Hellström-Lindberg, Eva, Jansen, Joop H, Dugas, Martin

“…Abstract Motivation The application of next-generation sequencing in research and particularly in clinical routine requires valid variant calling results…”
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The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains by Marteijn, J A, van der Meer, L T, Smit, J J, Noordermeer, S M, Wissink, W, Jansen, P, Swarts, H G, Hibbert, R G, de Witte, T, Sixma, T K, Jansen, J H, van der Reijden, B A

“…Ubiquitination plays a major role in many aspects of hematopoiesis. Alterations in ubiquitination have been implicated in hematological cancer. The ubiquitin…”
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The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension by Smit, Judith J, Monteferrario, Davide, Noordermeer, Sylvie M, van Dijk, Willem J, van der Reijden, Bert A, Sixma, Titia K

“…Activation of the NF‐κB pathway requires the formation of Met1‐linked ‘linear’ ubiquitin chains on NEMO, which is catalysed by the Linear Ubiquitin Chain…”
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Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals by van Zeventer, Isabelle A., de Graaf, Aniek O., Wouters, Hanneke J.C.M., van der Reijden, Bert A., van der Klauw, Melanie M., de Witte, Theo, Jonker, Marianne A., Malcovati, Luca, Jansen, Joop H., Huls, Gerwin

“…Anemia is a major and currently poorly understood clinical manifestation of hematopoietic aging. Upon aging, hematopoietic clones harboring acquired…”
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Clonal evolution in myelodysplastic syndromes by da Silva-Coelho, Pedro, Kroeze, Leonie I., Yoshida, Kenichi, Koorenhof-Scheele, Theresia N., Knops, Ruth, van de Locht, Louis T., de Graaf, Aniek O., Massop, Marion, Sandmann, Sarah, Dugas, Martin, Stevens-Kroef, Marian J., Cermak, Jaroslav, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, de Witte, Theo, Blijlevens, Nicole M. A., Muus, Petra, Huls, Gerwin, van der Reijden, Bert A., Ogawa, Seishi, Jansen, Joop H.

“…Cancer development is a dynamic process during which the successive accumulation of mutations results in cells with increasingly malignant characteristics…”
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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes by Jansen, Joop H, Nikoloski, Gorica, Langemeijer, Saskia M C, Kuiper, Roland P, Knops, Ruth, Massop, Marion, Tönnissen, Evelyn R L T M, van der Heijden, Adrian, Scheele, Theresia N, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A

“…In myelodysplastic syndromes (MDS), deletions of chromosome 7 or 7q are common and correlate with a poor prognosis. The relevant genes on chromosome 7 are…”
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Acquired mutations in TET2 are common in myelodysplastic syndromes by Jansen, Joop H, Langemeijer, Saskia M C, Kuiper, Roland P, Berends, Marieke, Knops, Ruth, Aslanyan, Mariam G, Massop, Marion, Stevens-Linders, Ellen, van Hoogen, Patricia, van Kessel, Ad Geurts, Raymakers, Reinier A P, Kamping, Eveline J, Verhoef, Gregor E, Verburgh, Estelle, Hagemeijer, Anne, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A

“…Myelodysplastic syndromes (MDS) represent a heterogeneous group of neoplastic hematopoietic disorders. Several recurrent chromosomal aberrations have been…”
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