Search Results - "Van der Minne, C E"

Induction and characterization of cytotoxic T-lymphocytes recognizing a mutated p21ras peptide presented by HLA-A0201 by Van Elsas, A, Nijman, H W, Van der Minne, C E, Mourer, J S, Kast, W M, Melief, C J, Schrier, P I

“…The ras oncogene is frequently found to be activated in human cancer through point mutations at codons 12, 13 or 61. We explored whether these altered p21ras…”
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Peptide-pulsed dendritic cells induce tumoricidal cytotoxic T lymphocytes from healthy donors against stably HLA-A0201-binding peptides from the Melan-A/MART-1 self antigen by van Elsas, A, van der Burg, S H, van der Minne, C E, Borghi, M, Mourer, J S, Melief, C J, Schrier, P I

“…The melanoma antigen Melan-A/MART-1 was screened for the presence of potential HLA-A*0201-binding cytotoxic T lymphocytes (CTL) epitopes. The immunodominant…”
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32OSuccessful use of interferon-alpha and adoptive T cell therapy for metastatic melanoma patients failing other treatment options by van der Kooij, M K, Verdegaal, E M E, Visser, M, De Bruin, L, Van der Minne, C E, Santegoets, S J, Welters, M J, Haanen, J B A G, Kapiteijn, E, van der Burg, S H

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CD4+ Th2 Cell Recognition of HLA-DR-Restricted Epitopes Derived from CAMEL: A Tumor Antigen Translated in an Alternative Open Reading Frame by Slager, Elisabeth H, Borghi, Martina, van der Minne, Carolien E, Aarnoudse, Corlien A, Havenga, Menzo J. E, Schrier, Peter I, Osanto, Susanne, Griffioen, Marieke

“…Tumor Ag NY-ESO-1 is an attractive target for immunotherapy of cancer, since both CD8(+) CTL and CD4(+) Th cells against NY-ESO-1 have been described…”
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Identification of Multiple HLA-DR-Restricted Epitopes of the Tumor-Associated Antigen CAMEL by CD4+ Th1/Th2 Lymphocytes by Slager, Elisabeth H, van der Minne, Caroline E, Kruse, Margreet, Krueger, Dilja D, Griffioen, Marieke, Osanto, Susanne

“…CD4(+) Th cells play an important role in the induction and maintenance of adequate CD8(+) T cell-mediated antitumor responses. Therefore, identification of…”
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Identification of Multiple HLA-DR-Restricted Epitopes of the Tumor- Associated Antigen CAMEL by CD4 super(+) Th1/Th2 Lymphocytes by Slager, E H, Van der Minne, CE, Kruese, M, Krueger, D D, Griffioen, M, Osanto, S

“…CD4 super(+) Th cells play an important role in the induction and maintenance of adequate CD8 super(+) T cell-mediated antitumor responses. Therefore,…”
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Induction of CAMEL NY-ESO-ORF2-specific CD8+ T cells upon stimulation with dendritic cells infected with a modified Ad5 vector expressing a chimeric Ad5 35 fiber by Slager, Elisabeth H, van der Minne, Caroline E, Goudsmit, Jaap, van Oers, Johanna M M, Kostense, Stefan, Havenga, Menzo J E, Osanto, Susanne, Griffioen, Marieke

“…Delivery of the full-length tumor antigen might be more successful in immunotherapy than single peptides and has the advantage that patients no longer need to…”
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Transfection of IL-2 augments CTL response to human melanoma cells in vitro: immunological characterization of a melanoma vaccine by van Elsas, A, Aarnoudse, C, van der Minne, C E, van der Spek, C W, Brouwenstijn, N, Osanto, S, Schrier, P I

“…We have transfected human melanoma cell line 518A2 with the cDNA encoding interleukin-2 (IL-2) or granulocyte-macrophage colony-stimulating factor (GM-CSF),…”
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