Search Results - "Van der Giezen, Dionne M."

Loss of Endogenous Bone Morphogenetic Protein-6 Aggravates Renal Fibrosis by Dendooven, Amélie, van Oostrom, Olivia, van der Giezen, Dionne M, Willem Leeuwis, Jan, Snijckers, Cristel, Joles, Jaap A, Robertson, Elizabeth J, Verhaar, Marianne C, Nguyen, Tri Q, Goldschmeding, Roel

“…Bone morphogenetic protein-6 (BMP-6) suppresses inflammatory genes in renal proximal tubular cells and regulates iron metabolism by inducing hepcidin. In…”
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In mice, proteinuria and renal inflammatory responses to albumin overload are strain-dependent by Ishola, David A., van der Giezen, Dionne M., Hahnel, Brunhilde, Goldschmeding, Roel, Kriz, Wilhelm, Koomans, Hein A., Joles, Jaap A.

“…Background. The availability of genetically modified mice has increased the need for relevant mouse models of renal disease, but widely used C57BL/6 mice often…”
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A perinatal nitric oxide donor increases renal vascular resistance and ameliorates hypertension and glomerular injury in adult fawn-hooded hypertensive rats by Koeners, Maarten P, Braam, Branko, van der Giezen, Dionne M, Goldschmeding, Roel, Joles, Jaap A

“…Enhancing perinatal nitric oxide (NO) availability persistently reduces blood pressure in spontaneously hypertensive rats. We hypothesize that this approach…”
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Oxidative stress in obstructive nephropathy by Dendooven, Amélie, Ishola Jr, David A., Nguyen, Tri Q., Van der Giezen, Dionne M., Kok, Robbert Jan, Goldschmeding, Roel, Joles, Jaap A.

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Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension by Racasan, Simona, Hahnel, Bruni, Van Dergiezen, Dionne M., Blezer, Erwin L., Goldschmeding, Roel, Braam, Branko, Kriz, Wilhem, Koomans, Hein A., Joles, Jaap A.

“…Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension. Exposure of normotensive rats to…”
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Oxidative stress in obstructive nephropathy by Dendooven, Amélie, Ishola Jr, David A., Nguyen, Tri Q., Van der Giezen, Dionne M., Kok, Robbert Jan, Goldschmeding, Roel, Joles, Jaap A.

“…Summary Unilateral ureteric obstruction (UUO) is one of the most commonly applied rodent models to study the pathophysiology of renal fibrosis. This model…”
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Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney by Falke, Lucas L., Dendooven, Amélie, Leeuwis, Jan Willem, Nguyen, Tri Q., van Geest, Rob J., van der Giezen, Dionne M., Broekhuizen, Roel, Lyons, Karen, Stoop, Reinout, Kemperman, Hans, Schlingemann, Reinier, Joles, Jaap A., Goldschmeding, Roel

“…Connective Tissue Growth Factor (CTGF/CCN2) is an important mediator of kidney fibrosis. Previous observations indicated that attenuation of CCN2 expression…”
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Connective Tissue Growth Factor Is Involved in Structural Retinal Vascular Changes in Long-Term Experimental Diabetes by Van Geest, Rob J., Leeuwis, Jan Willem, Dendooven, Amélie, Pfister, Frederick, Bosch, Klazien, Hoeben, Kees A., Vogels, Ilse M.C., Van der Giezen, Dionne M., Dietrich, Nadine, Hammes, Hans-Peter, Goldschmeding, Roel, Klaassen, Ingeborg, Van Noorden, Cornelis J.F., Schlingemann, Reinier O.

“…Early retinal vascular changes in the development of diabetic retinopathy (DR) include capillary basal lamina (BL) thickening, pericyte loss and the…”
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Perinatal L-Arginine and Antioxidant Supplements Reduce Adult Blood Pressure in Spontaneously Hypertensive Rats by Racasan, Simona, Braam, Branko, van der Giezen, Dionne M, Goldschmeding, Roel, Boer, Peter, Koomans, Hein A, Joles, Jaap A

“…Embryo cross-transplantation and cross-fostering between spontaneously hypertensive rats (SHR) and normotensive rats (WKY) suggest that perinatal environment…”
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Perinatal Micronutrient Supplements Ameliorate Hypertension and Proteinuria in Adult Fawn-Hooded Hypertensive Rats by Koeners, Maarten P., Braam, Branko, van der Giezen, Dionne M., Goldschmeding, Roel, Joles, Jaap A.

“…Background In fawn-hooded hypertensive (FHH) rats, a model of hypertension, impaired preglomerular resistance, hyperfiltration, and progressive renal injury,…”
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Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys by Leeuwis, Jan Willem, Nguyen, Tri Q, Chuva de Sousa Lopes, Susana M, van der Giezen, Dionne M, van der Ven, Kevin, Rouw, Peter JH, Offerhaus, G Johan A, Mummery, Christine L, Goldschmeding, Roel

“…Bone morphogenetic protein 7 (BMP7) is a key determinant of renal response to injury, exhibiting strong protective as well as regenerative potential in a…”
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Protein restriction in lactation confers nephroprotective effects in the male rat and is associated with increased antioxidant expression by Tarry-Adkins, Jane L, Joles, Jaap A, Chen, Jian-Hua, Martin-Gronert, Malgorzata S, van der Giezen, Dionne M, Goldschmeding, Roel, Hales, C Nicholas, Ozanne, Susan E

“…Telomere shortening has been implicated in the aging process and various age-associated disorders, including renal disease. Moreover, oxidative stress has been…”
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Implementation of accurate and fast DNA cytometry by confocal microscopy in 3D by Ploeger, Lennert S, Huisman, André, van der Gugten, Jurryt, van der Giezen, Dionne M, Beliën, Jeroen A M, Abbaker, Abdelhadi Y, Dullens, Hub F J, Grizzle, William, Poulin, Neal M, Meijer, Gerrit A, van Diest, Paul J

“…DNA cytometry is a powerful method for measuring genomic instability. Standard approaches that measure DNA content of isolated cells may induce selection bias…”
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Direct visualization of Smad 1/5/8―mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys by WILLEM LEEUWIS, Jan, NGUYEN, Tri Q, CHUVA DE SOUSA LOPES, Susana M, VAN DER GIEZEN, Dionne M, VAN DER VEN, Kevin, ROUW, Peter Jh, OFFERHAUS, G. Johan A, MUMMERY, Christine L, GOLDSCHMEDING, Roel

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Oxidative stress in obstructive nephropathy: Oxidative stress in nephropathy by Dendooven, Amélie, Ishola Jr, David A., Nguyen, Tri Q., Van der Giezen, Dionne M., Kok, Robbert Jan, Goldschmeding, Roel, Joles, Jaap A.

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