Search Results - "Van den Berge, D L"
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Chronic hypoxia modulates tumour cell radioresponse through cytokine-inducible nitric oxide synthase
Published in British journal of cancer (20-04-2001)“…Chronic hypoxia up-regulated the mRNA and protein expression of inducible nitric oxide synthase (iNOS) in EMT-6 tumour cells exposed to interferon (IFN)-gamma…”
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Radiosensitization of hypoxic tumour cells by S-nitroso-N-acetylpenicillamine implicates a bioreductive mechanism of nitric oxide generation
Published in British journal of cancer (01-03-1999)“…The radiosensitizing activity of S-nitroso-N-acetylpenicillamine (SNAP), a nitric oxide (NO) donor, was assessed in a model of non-metabolic hypoxia achieved…”
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Low-level doxorubicin resistance in P-glycoprotein-negative human pancreatic tumour PSN1/ADR cells implicates a brefeldin A-sensitive mechanism of drug extrusion
Published in British journal of cancer (01-03-1996)“…The human pancreatic tumour cell line PSN1/ADR, stepwise selected in 17-510 nM doxorubicin, displayed a multidrug resistance not conferred by P-glycoprotein…”
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Activation of inducible nitric oxide synthase results in nitric oxide-mediated radiosensitization of hypoxic EMT-6 tumor cells
Published in Cancer research (Chicago, Ill.) (15-12-1998)“…EMT-6 cells treated for 16 h with 1-10 units/ml IFN-gamma showed a gradual activation of inducible nitric oxide synthase (iNOS) in Western and Northern blots,…”
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Intrinsic radiosensitivity of human pancreatic tumour cells and the radiosensitising potency of the nitric oxide donor sodium nitroprusside
Published in British journal of cancer (01-12-1996)“…A panel of eight human pancreatic tumour cell lines displayed high intrinsic radioresistance, with mean inactivation doses between 2.4 and 6.5 Gy, similar to…”
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NF-κB inhibition impairs the radioresponse of hypoxic EMT-6 tumour cells through downregulation of inducible nitric oxide synthase
Published in British journal of cancer (13-01-2003)“…Hypoxic EMT-6 tumour cells displayed a high level of inducible nitric oxide synthase (iNOS) and an increased radiosensitivity after a 16 h exposure to…”
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7
Imaging in radiotherapy
Published in European journal of radiology (01-10-2000)“…Radiotherapy, more then any other treatment modality, relies heavily and often exclusively on medical imaging to determine the extent of disease and the…”
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3D conformal intensity-modulated radiotherapy planning: interactive optimization by constrained matrix inversion
Published in Radiotherapy and oncology (01-04-1998)“…Background and purpose: This paper presents a method for interactive optimization of 3D conformal intensity-modulated radiotherapy plans employing a quadratic…”
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Evidence for abrogation of oncogene-induced radioresistance of mammary cancer cells by hexadecylphosphocholine in vitro
Published in European journal of cancer (1990) (1993)“…Hexadecylphosphocholine (HePC), an experimental and clinical antitumour agent of the alkyllysophospholipid group, was tested for its radiosensitising effect on…”
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NF-kappaB inhibition impairs the radioresponse of hypoxic EMT-6 tumour cells through downregulation of inducible nitric oxide synthase
Published in British journal of cancer (13-01-2003)“…Hypoxic EMT-6 tumour cells displayed a high level of inducible nitric oxide synthase (iNOS) and an increased radiosensitivity after a 16 h exposure to…”
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NF- B inhibition impairs the radioresponse of hypoxic EMT-6 tumour cells through downregulation of inducible nitric oxide synthase
Published in British journal of cancer (13-01-2003)“…Hypoxic EMT-6 tumour cells displayed a high level of inducible nitric oxide synthase (iNOS) and an increased radiosensitivity after a 16 h exposure to…”
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Macrophages enhance the radiosensitizing activity of lipid A: a novel role for immune cells in tumor cell radioresponse
Published in International journal of radiation oncology, biology, physics (01-10-2004)“…This study examines whether activated macrophages may radiosensitize tumor cells through the release of proinflammatory mediators. RAW 264.7 macrophages were…”
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Dutch Hospital Drug Formularies: pharmacotherapeutic variation and conservatism, but concurrence with national pharmacotherapeutic guidelines
Published in British journal of clinical pharmacology (01-03-2000)“…Aims This research examines current hospital drug formularies (HDFs) of all Dutch general hospitals. It assesses the extent to which they recommend the same…”
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