Search Results - "Van de Vijver, M."

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets by Turner, N, Lambros, M B, Horlings, H M, Pearson, A, Sharpe, R, Natrajan, R, Geyer, F C, van Kouwenhove, M, Kreike, B, Mackay, A, Ashworth, A, van de Vijver, M J, Reis-Filho, J S

“…Triple negative breast cancers (TNBCs) have a relatively poor prognosis and cannot be effectively treated with current targeted therapies. We searched for…”
Get full text

Refinement of breast cancer classification by molecular characterization of histological special types by Weigelt, B, Horlings, HM, Kreike, B, Hayes, MM, Hauptmann, M, Wessels, LFA, de Jong, D, Van de Vijver, MJ, Veer, LJ Van't, Peterse, JL

“…Most invasive breast cancers are classified as invasive ductal carcinoma not otherwise specified (IDC NOS), whereas about 25% are defined as histological…”
Get full text

A specific gene expression signature for visceral organ metastasis in breast cancer by Savci-Heijink, C D, Halfwerk, H, Koster, J, Horlings, H M, van de Vijver, M J

“…Visceral organ metastasis is associated with poor survival outcomes in terms of metastasis free- and overall survival in breast carcinomas. Identification of a…”
Get full text

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer by Liu, G, Bollig-Fischer, A, Kreike, B, van de Vijver, M J, Abrams, J, Ethier, S P, Yang, Z -Q

“…Earlier, mapping of the 9p23–24 amplicon in esophageal cancer cell lines led us to the positional cloning of gene amplified in squamous cell carcinoma 1 (…”
Get full text

Epithelial-to-mesenchymal transition status of primary breast carcinomas and its correlation with metastatic behavior by Savci-Heijink, C. D., Halfwerk, H., Hooijer, G. K. J., Koster, J., Horlings, H. M., Meijer, S. L., van de Vijver, M. J.

“…Background Epithelial-to-mesenchymal transition (EMT) has been implicated as an important step in the development of distant metastases. We therefore wished to…”
Get full text

Very low local recurrence rates after breast-conserving therapy: analysis of 8485 patients treated over a 28-year period by Bosma, S. C. J., van der Leij, F., van Werkhoven, E., Bartelink, H., Wesseling, J., Linn, S., Rutgers, E. J., van de Vijver, M. J., Elkhuizen, P. H. M.

“…The purpose of this study was to study the impact of changes in clinical practice on outcome in patients treated with breast-conserving therapy (BCT) over a…”
Get full text

A prospective evaluation of a breast cancer prognosis signature in the observational RASTER study by Drukker, C.A., Bueno‐de‐Mesquita, J.M., Retèl, V.P., Harten, W.H., Tinteren, H., Wesseling, J., Roumen, R.M.H., Knauer, M., Veer, L.J., Sonke, G.S., Rutgers, E.J.T., Vijver, M.J., Linn, S.C.

“…The 70‐gene signature (MammaPrint™) has been developed on retrospective series of breast cancer patients to predict the risk of breast cancer distant…”
Get full text

Reduction in Acquisition of Vancomycin-Resistant Enterococcus after Enforcement of Routine Environmental Cleaning Measures by Hayden, Mary K., Bonten, Marc J. M., Blom, Donald W., Lyle, Elizabeth A., van de Vijver, David A. M. C., Weinstein, Robert A.

“…Background. The role of environmental contamination in nosocomial cross-transmission of antibiotic-resistant bacteria has been unresolved. Using…”
Get full text

Persistent Transmission of HCV among Men Who Have Sex with Men despite Widespread Screening and Treatment with Direct-Acting Antivirals by Popping, Stephanie, Cuypers, Lize, Claassen, Mark A. A, van den Berk, Guido E, De Weggheleire, Anja, Arends, Joop E, Boerekamps, Anne, Molenkamp, Richard, Koopmans, Marion P. G, Verbon, Annelies, Boucher, Charles A. B, Rijnders, Bart, van de Vijver, David A. M. C

“…Background: In the Netherlands, unrestricted access to direct-acting antivirals (DAAs) halved the incidence of acute hepatitis C virus (HCV) infections among…”
Get full text

Assessment of a HER2 scoring system for gastric cancer: results from a validation study by Hofmann, M, Stoss, O, Shi, D, Büttner, R, Van De Vijver, M, Kim, W, Ochiai, A, Rüschoff, J, Henkel, T

“…Aims:  Human epidermal growth factor receptor 2 (HER2) overexpression/amplification is implicated in the development of various solid tumour types. Validated…”
Get full text

Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer by Nederlof, I., Hajizadeh, S., Sobhani, F., Raza, S. E. A., AbdulJabbar, K., Harkes, R., van de Vijver, M. J., Salgado, R., Desmedt, C., Kok, M., Yuan, Y., Horlings, H. M.

“…In estrogen-receptor-positive, HER2-negative (ER + HER2 − ) breast cancer, higher levels of tumor infiltrating lymphocytes (TILs) are often associated with a…”
Get full text

Clinical outcome of prophylactic oophorectomy in BRCA1 BRCA2 mutation carriers and events during follow-up by OLIVIER, R. I, VAN BEURDEN, M, LUBSEN, M. A. C, ROOKUS, M. A, MOOIJ, T. M, VAN DE VIJVER, M. J, VAN'T VEER, L. J

“…A retrospective study was performed to assess the histopathologic findings in high-risk women undergoing bilateral prophylactic (salpingo)-oophorectomy. The…”
Get full text

Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types by Starmans, M H W, Krishnapuram, B, Steck, H, Horlings, H, Nuyten, D S A, van de Vijver, M J, Seigneuric, R, Buffa, F M, Harris, A L, Wouters, B G, Lambin, P

“…Tumour proliferation is one of the main biological phenotypes limiting cure in oncology. Extensive research is being performed to unravel the key players in…”
Get full text

ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy by Veenstra, V. L., Damhofer, H., Waasdorp, C., van Rijssen, L. B., van de Vijver, M. J., Dijk, F., Wilmink, H. W., Besselink, M. G., Busch, O. R., Chang, D. K., Bailey, P. J., Biankin, A. V., Kocher, H. M., Medema, J. P., Li, J. S., Jiang, R., Pierce, D. W., van Laarhoven, H. W. M., Bijlsma, M. F.

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma that harbors tumor-promoting properties. No good biomarkers exist to monitor the…”
Get full text

HLA-G Expression Is an Independent Predictor for Improved Survival in High Grade Ovarian Carcinomas by Jordanova, E. S., Vijver, M. J. van de, Kenter, G. G., Dijk, F., Savci-Heijink, C. D., Buist, M. R., Rutten, M. J.

“…Aberrant expression of human leukocyte antigens (HLA) class I has prognostic importance in various cancers. Here, we evaluated the prognostic value of…”
Get full text

Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcome by FANEYTE, I. F, SCHRAMA, J. G, PETERSE, J. L, REMIJNSE, P. L, RODENHUIS, S, VAN DE VIJVER, M. J

“…The aim of this study was to provide a better insight into breast cancer response to chemotherapy. Chemotherapy improves outcome in breast cancer patients. The…”
Get full text

Efficacy of high-dose alkylating chemotherapy in HER2/neu-negative breast cancer by Rodenhuis, S., Bontenbal, M., van Hoesel, Q.G.C.M., Smit, W.M., Nooij, M.A., Voest, E.E., van der Wall, E., Hupperets, P., van Tinteren, H., Peterse, J.L., van de Vijver, M.J., de Vries, E.G.E.

“…Background: High-dose chemotherapy in the adjuvant treatment of breast cancer has been abandoned by many. Patients and methods: 885 patients with stage III…”
Get full text

Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients by VAN DER HAGE, J. A, VAN DEN BROEK, L. J. C. M, LEGRAND, C, CLAHSEN, P. C, BOSCH, C. J. A, ROBANUS-MAANDAG, E. C, VAN DE VELDE, C. J. H, VAN DE VIJVER, M. J

“…The RPS6KB1 gene is amplified and overexpressed in approximately 10% of breast carcinomas and has been found associated with poor prognosis. We studied the…”
Get full text

The impact of inter-observer variation in pathological assessment of node-negative breast cancer on clinical risk assessment and patient selection for adjuvant systemic treatment by Bueno-de-Mesquita, J. M., Nuyten, D. S. A., Wesseling, J., van Tinteren, H., Linn, S. C., van de Vijver, M. J.

“…Background: It is well known that there is considerable inter-observer variability in assessment of the pathological parameters that are used to select…”
Get full text

Inter-Laboratory Reproducibility of Inducible HIV-1 Reservoir Quantification by TILDA by Lungu, Cynthia, Procopio, Francesco A, Overmars, Ronald J, Beerkens, Rob J J, Voermans, Jolanda J C, Rao, Shringar, Prins, Henrieke A B, Rokx, Casper, Pantaleo, Giuseppe, Vijver, David A M C van de, Mahmoudi, Tokameh, Boucher, Charles A B, Gruters, Rob A, Kampen, Jeroen J A van

“…Substantial efforts to eliminate or reduce latent HIV-1 reservoirs are underway in clinical trials and have created a critical demand for sensitive, accurate,…”
Get full text