Search Results - "Van Wagoner, D"
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Ascorbate Attenuates Atrial Pacing-Induced Peroxynitrite Formation and Electrical Remodeling and Decreases the Incidence of Postoperative Atrial Fibrillation
Published in Circulation research (14-09-2001)“…Atrial fibrillation (AF), the most common chronic arrhythmia, increases the risk of stroke and is an independent predictor of mortality. Available…”
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Atrial L-Type Ca2+ Currents and Human Atrial Fibrillation
Published in Circulation research (03-09-1999)“…Chronic atrial fibrillation (AF) is characterized by decreased atrial contractility, shortened action potential duration, and decreased accommodation of action…”
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3
Virtual Electrode-Induced Phase Singularity: A Basic Mechanism of Defibrillation Failure
Published in Circulation research (04-05-1998)“…Delivery of a strong electric shock to the heart remains the only effective therapy against ventricular fibrillation. Despite significant improvements in…”
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0614 Diurnal Patterning of Autonomic Measures in Sleep Apnea and Paroxysmal Atrial Fibrillation and Response to Continuous Positive Airway Pressure Therapy
Published in Sleep (New York, N.Y.) (27-05-2020)“…Abstract Introduction Diurnal patterning of autonomic function in paroxysmal atrial fibrillation (PAF) and sleep disordered breathing (SDB) is unknown. We…”
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Mechanosensitive Gating of Atrial ATP-Sensitive Potassium Channels
Published in Circulation research (01-05-1993)“…Cell-attached and inside-out excised-patch recording techniques were used to search for mechanosensitive ion channels in neonatal and adult rat atrial…”
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Virtual Electrode–Induced Reexcitation: A Mechanism of Defibrillation
Published in Circulation research (26-11-1999)“…Mechanisms of defibrillation remain poorly understood. Defibrillation success depends on the elimination of fibrillation without shock-induced…”
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C-Reactive protein elevation in patients with atrial arrhythmias: Inflammatory mechanisms and persistence of atrial fibrillation
Published in Circulation (New York, N.Y.) (11-12-2001)“…Atrial fibrillation (AF) may persist due to structural changes in the atria that are promoted by inflammation. C-reactive protein (CRP), a marker of systemic…”
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Changes in myofilament proteins, but not Ca²⁺ regulation, are associated with a high-fat diet-induced improvement in contractile function in heart failure
Published in American journal of physiology. Heart and circulatory physiology (01-10-2011)“…Pathological conditions such as diabetes, insulin resistance, and obesity are characterized by elevated plasma and myocardial lipid levels and have been…”
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Impaired myofibrillar energetics and oxidative injury during human atrial fibrillation
Published in Circulation (New York, N.Y.) (10-07-2001)“…Atrial fibrillation (AF) is associated with severe contractile dysfunction and structural and electrophysiological remodeling. Mechanisms responsible for…”
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Outward K+ current densities and Kv1.5 expression are reduced in Chronic human atrial fibrillation
Published in Circulation research (01-06-1997)“…Chronic atrial fibrillation is associated with a shortening of the atrial action potential duration and atrial refractory period. To test the hypothesis that…”
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Phenylephrine suppresses outward K+ currents in rat atrial myocytes
Published in The American journal of physiology (01-09-1996)“…The modulation of whole cell K+ currents by the alpha 1-adrenergic agonist, phenylephrine, was studied in isolated rat atrial myocytes by use of…”
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Pathophysiology and prevention of atrial fibrillation
Published in Circulation (New York, N.Y.) (06-02-2001)Get full text
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Arachidonic acid and endothelin potentiate Ca2+ transients in rat cardiac myocytes via inhibition of distinct K+ channels
Published in The Journal of biological chemistry (25-12-1993)“…The release of arachidonic acid by phospholipases in response to cell surface receptor activation may be an important step in the initiation of inotropic…”
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The burden of proof: The current state of atrial fibrillation prevention and treatment trials
Published in Heart rhythm (01-05-2017)“…Atrial fibrillation (AF) is an age-related arrhythmia of enormous socioeconomic significance. In recent years, our understanding of the basic mechanisms that…”
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Molecular Basis of Electrical Remodeling in Atrial Fibrillation
Published in Journal of molecular and cellular cardiology (01-06-2000)“…D. R. Van Wagoner and J. M. Nerbonne. Molecular Basis of Electrical Remodeling in Atrial Fibrillation.Journal of Molecular and Cellular Cardiology (2000) 32,…”
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Perforated Peptic Ulcer in a Child With a Vagus Nerve Stimulator for Seizure Control
Published in Brain stimulation (01-11-2013)Get full text
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Phenylephrine-induced Ca2+ oscillations in canine pulmonary artery smooth muscle cells
Published in Circulation research (01-11-1997)“…Modulation of [Ca2+]i in response to receptor activation is a critical determinant of vascular smooth muscle tone. In this study, we examined the effect of…”
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Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure
Published in Circulation. Heart failure (01-01-2023)“…The gut microbiota-dependent metabolite phenylacetylgutamine (PAGln) is both associated with atherothrombotic heart disease in humans, and mechanistically…”
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Redox Modulation of Cardiac Electrical Activity
Published in Journal of cardiovascular electrophysiology (01-02-2001)Get full text
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Pharmacologic Relevance of K+Channel Remodeling in Atrial Fibrillation
Published in Journal of molecular and cellular cardiology (01-10-2000)Get full text
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