Search Results - "Van Velkinburgh, Jennifer C."

Global mapping of H3K4me1 and H3K4me3 reveals the chromatin state-based cell type-specific gene regulation in human Treg cells by Tian, Yi, Jia, Zhengcai, Wang, Jun, Huang, Zemin, Tang, Jun, Zheng, Yanhua, Tang, Yan, Wang, Qinghong, Tian, Zhiqiang, Yang, Di, Zhang, Yi, Fu, Xiaolan, Song, Jianxun, Liu, Shunli, van Velkinburgh, Jennifer C, Wu, Yuzhang, Ni, Bing

“…Regulatory T cells (Treg) contribute to the crucial immunological processes of self-tolerance and immune homeostasis. Genomic mechanisms that regulate cell…”
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An integrated clinico-metabolomic model improves prediction of death in sepsis by Langley, Raymond J, Tsalik, Ephraim L, van Velkinburgh, Jennifer C, Glickman, Seth W, Rice, Brandon J, Wang, Chunping, Chen, Bo, Carin, Lawrence, Suarez, Arturo, Mohney, Robert P, Freeman, Debra H, Wang, Mu, You, Jinsam, Wulff, Jacob, Thompson, J Will, Moseley, M Arthur, Reisinger, Stephanie, Edmonds, Brian T, Grinnell, Brian, Nelson, David R, Dinwiddie, Darrell L, Miller, Neil A, Saunders, Carol J, Soden, Sarah S, Rogers, Angela J, Gazourian, Lee, Fredenburgh, Laura E, Massaro, Anthony F, Baron, Rebecca M, Choi, Augustine M K, Corey, G Ralph, Ginsburg, Geoffrey S, Cairns, Charles B, Otero, Ronny M, Fowler, Jr, Vance G, Rivers, Emanuel P, Woods, Christopher W, Kingsmore, Stephen F

“…Sepsis is a common cause of death, but outcomes in individual patients are difficult to predict. Elucidating the molecular processes that differ between sepsis…”
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Hepatitis B virus induces IL-23 production in antigen presenting cells and causes liver damage via the IL-23/IL-17 axis by Wang, Qinghong, Zhou, Jijun, Zhang, Bei, Tian, Zhiqiang, Tang, Jun, Zheng, Yanhua, Huang, Zemin, Tian, Yi, Jia, Zhengcai, Tang, Yan, van Velkinburgh, Jennifer C, Mao, Qing, Bian, Xiuwu, Ping, Yifang, Ni, Bing, Wu, Yuzhang

“…IL-23 regulates myriad processes in the innate and adaptive immune systems, and is a critical mediator of the proinflammatory effects exerted by Th17 cells in…”
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Discriminative Value of Inflammatory Biomarkers for Suspected Sepsis by Tsalik, Ephraim L., MD, PhD, Jaggers, L. Brett, MD, Glickman, Seth W., MD, Langley, Raymond J., PhD, van Velkinburgh, Jennifer C., PhD, Park, Lawrence P., PhD, Fowler, Vance G., MD, Cairns, Charles B., MD, Kingsmore, Stephen F., MB, CHB, BAO, DSC, Woods, Christopher W., MD, MPH

“…Abstract Background Circulating biomarkers can facilitate sepsis diagnosis, enabling early management and improved outcomes. Procalcitonin (PCT) has been…”
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Multiplex PCR To Diagnose Bloodstream Infections in Patients Admitted from the Emergency Department with Sepsis by Tsalik, Ephraim L, Jones, Daphne, Nicholson, Bradly, Waring, Lynette, Liesenfeld, Oliver, Park, Lawrence P, Glickman, Seth W, Caram, Lauren B, Langley, Raymond J, van Velkinburgh, Jennifer C, Cairns, Charles B, Rivers, Emanuel P, Otero, Ronny M, Kingsmore, Stephen F, Lalani, Tahaniyat, Fowler, Vance G, Woods, Christopher W

“…Sepsis is caused by a heterogeneous group of infectious etiologies. Early diagnosis and the provision of appropriate antimicrobial therapy correlate with…”
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Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans by Ahn, Sun Hee, Tsalik, Ephraim L, Cyr, Derek D, Zhang, Yurong, van Velkinburgh, Jennifer C, Langley, Raymond J, Glickman, Seth W, Cairns, Charles B, Zaas, Aimee K, Rivers, Emanuel P, Otero, Ronny M, Veldman, Tim, Kingsmore, Stephen F, Lucas, Joseph, Woods, Christopher W, Ginsburg, Geoffrey S, Fowler, Jr, Vance G

“…Staphylococcus aureus causes a spectrum of human infection. Diagnostic delays and uncertainty lead to treatment delays and inappropriate antibiotic use. A…”
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Logical hypothesis:Low FODMAP diet to prevent diverticulitis by Uno, Yoshiharu, van Velkinburgh, Jennifer C

“…Despite little evidence for the therapeutic benefits of a high-fiber diet for diverticulitis,it is commonly recommended as part of the clinical management.The…”
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Identification of Diagnostic Biomarkers for Infection in Premature Neonates by Kingsmore, Stephen F., Kennedy, Neil, Halliday, Henry L., Van Velkinburgh, Jennifer C., Zhong, Shengiang, Gabriel, Vanessa, Grant, Judith, Beavis, William D., Tchernev, Velizar T., Perlee, Lorah, Lejnine, Serguei, Grimwade, Brian, Sorette, Martin, Edgar, J. David M.

“…Infection is a leading cause of neonatal morbidity and mortality worldwide. Premature neonates are particularly susceptible to infection because of physiologic…”
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Conserved Transcriptional Regulatory Domains of the pdx-1 Gene by Gerrish, Kevin, Van Velkinburgh, Jennifer C, Stein, Roland

“…The pancreas and duodenum homeobox protein 1 (PDX-1) homeodomain-containing transcription factor affects both pancreatic endocrine cell development and adult…”
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Salmonella enterica Serovar Typhimurium Resistance to Bile: Identification and Characterization of the tolQRA Cluster by Prouty, Angela M, Van Velkinburgh, Jennifer C, Gunn, John S

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Innate lymphoid cells involve in tumorigenesis by Tian, Zhiqiang, van Velkinburgh, Jennifer C, Wu, Yuzhang, Ni, Bing

“…Innate lymphoid cells (ILCs) promptly initiate cytokine responses to pathogen exposure in the mucosa and mucosal‐associated lymphoid tissues. ILCs were…”
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Pathogen-specific innate immune response by Zeytun, Ahmet, van Velkinburgh, Jennifer C, Pardington, Paige E, Cary, Robert R, Gupta, Goutam

“…This chapter summarizes our studies on the three toll-like receptor pathways, namely TLR4, TLR2, and TLR3, induced by lipopolysaccharides (LPS), peptidoglycan…”
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Interactions between Areas I and II Direct pdx-1 Expression Specifically to Islet Cell Types of the Mature and Developing Pancreas by Van Velkinburgh, Jennifer C., Samaras, Susan E., Gerrish, Kevin, Artner, Isabella, Stein, Roland

“…PDX-1 regulates transcription of genes involved in islet β cell function and pancreas development. Islet-specific expression is controlled by 5′-flanking…”
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MODY7 Gene, KLF11, Is a Novel p300-dependent Regulator of Pdx-1 (MODY4) Transcription in Pancreatic Islet β Cells by Fernandez-Zapico, Martin E., van Velkinburgh, Jennifer C., Gutiérrez-Aguilar, Ruth, Neve, Bernadette, Froguel, Philippe, Urrutia, Raul, Stein, Roland

“…Pdx-1 (pancreatic-duodenal homeobox-1), a MODY4 homeodomain transcription factor, serves as a master regulator in the pancreas because of its importance during…”
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Role of Ets Proteins in Development, Differentiation, and Function of T-Cell Subsets by Liu, Mian, Gao, Weiwu, van Velkinburgh, Jennifer C., Wu, Yuzhang, Ni, Bing, Tian, Yi

“…Through positive selection, double‐positive cells in the thymus differentiate into CD4+ or CD8+ T single‐positive cells that subsequently develop into…”
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Innate Lymphoid Cells: A Promising New Regulator in Fibrotic Diseases by Zhang, Yi, Tang, Jun, Tian, Zhiqiang, van Velkinburgh, Jennifer C., Song, Jianxun, Wu, Yuzhang, Ni, Bing

“…Fibrosis is a consequence of chronic inflammation and the persistent accumulation of extracellular matrix, for which the cycle of tissue injury and repair…”
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Pivotal roles of the interleukin-23/T helper 17 cell axis in hepatitis B by Huang, Zemin, van Velkinburgh, Jennifer C., Ni, Bing, Wu, Yuzhang

“…T helper 17 (Th17) cells are a newly identified subset of T helper cells that play important roles in host defense against extracellular bacteria, as well as…”
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Renal systems biology of patients with systemic inflammatory response syndrome by Tsalik, Ephraim L, Willig, Laurel K, Rice, Brandon J, van Velkinburgh, Jennifer C, Mohney, Robert P, McDunn, Jonathan E, Dinwiddie, Darrell L, Miller, Neil A, Mayer, Eric S, Glickman, Seth W, Jaehne, Anja K, Glew, Robert H, Sopori, Mohan L, Otero, Ronny M, Harrod, Kevin S, Cairns, Charles B, Fowler, Vance G, Rivers, Emanuel P, Woods, Christopher W, Kingsmore, Stephen F, Langley, Raymond J

“…A systems biology approach was used to comprehensively examine the impact of renal disease and hemodialysis (HD) on patient response during critical illness…”
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Von Willebrand factor protects against acute CCl4-induced hepatotoxicity through phospho-p38 MAPK signaling pathway inhibition by Sun, Hai-Jian, Chen, Jian, Zhang, Hao, Ni, Bing, van Velkinburgh, Jennifer C., Liu, Yao, Wu, Yu-Zhang, Yang, Xia

“…The blood glycoprotein von Willebrand factor (vWF) is involved in coagulopathy and inflammation; however, its role in the pathogenesis of acute liver failure,…”
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Disease Progression in Hemodynamically Stable Patients Presenting to the Emergency Department With Sepsis by Glickman, Seth W., Cairns, Charles B., Otero, Ronny M., Woods, Christopher W., Tsalik, Ephraim L., Langley, Raymond J., Van Velkinburgh, Jennifer C., Park, Lawrence P., Glickman, Lawrence T., Fowler, Vance G., Kingsmore, Stephen F., Rivers, Emanuel P.

“…Background:  Aggressive diagnosis and treatment of patients presenting to the emergency department (ED) with septic shock has been shown to reduce mortality…”
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