Search Results - "Van Tine, B"

Masitinib in advanced gastrointestinal stromal tumor (GIST) after failure of imatinib: A randomized controlled open-label trial by Adenis, A., Blay, J.-Y., Bui-Nguyen, B., Bouché, O., Bertucci, F., Isambert, N., Bompas, E., Chaigneau, L., Domont, J., Ray-Coquard, I., Blésius, A., Van Tine, B.A., Bulusu, V.R., Dubreuil, P., Mansfield, C.D., Acin, Y., Moussy, A., Hermine, O., Le Cesne, A.

“…Masitinib is a highly selective tyrosine kinase inhibitor with activity against the main oncogenic drivers of gastrointestinal stromal tumor (GIST). Masitinib…”
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Clinical Outcomes and Prognostic Features of Angiosarcoma: Significance of Prior Radiation Therapy by Merfeld, E., Gabani, P., Spraker, M.B., Zoberi, I., Kim, H., Van Tine, B., Chrisinger, J., Michalski, J.M.

“…Angiosarcoma is a rare and aggressive malignancy with a poor prognosis. There is limited literature describing prognostic factors and guidelines for treatment…”
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Improved clinical trial enrollments for uterine leiomyosarcoma patients after gynecologic oncology partnership with a sarcoma center by Lange, S.E.S, Liu, J, Adkins, D.R, Powell, M.A, Van Tine, B.A, Mutch, D.G

“…Abstract Objective A retrospective chart review was performed to determine patient outcomes before and after partnership by gynecologic oncologists (GYN/ONC)…”
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Phase II study of MLN8237 (Alisertib) in advanced/metastatic sarcoma by Dickson, M.A., Mahoney, M.R., Tap, W.D., D'Angelo, S.P., Keohan, M.L., Van Tine, B.A., Agulnik, M., Horvath, L.E., Nair, J.S., Schwartz, G.K.

“…Aurora kinase A (AURKA) is commonly overexpressed in sarcoma. The inhibition of AURKA by shRNA or by a specific AURKA inhibitor blocks in vitro proliferation…”
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Efficacy and tolerability of trabectedin in elderly patients with sarcoma: subgroup analysis from a phase III, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma by Jones, R.L., Demetri, G.D., Schuetze, S.M., Milhem, M., Elias, A., Van Tine, B.A., Hamm, J., McCarthy, S., Wang, G., Parekh, T., Knoblauch, R., Hensley, M.L., Maki, R.G., Patel, S., von Mehren, M.

“…Treatment options for soft tissue sarcoma (STS) patients aged ≥65years (elderly) can be limited by concerns regarding the increased risk of toxicity associated…”
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Multicenter, open-label phase II study of daily oral regorafenib for chemotherapy-refractory, metastatic and locally advanced angiosarcoma by Agulnik, M., van Tine, B.A., Attia, S., Rademaker, A., Milhem, M., Okuno, S.H.

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A phase II study of tivozanib in patients with metastatic and nonresectable soft-tissue sarcomas by Agulnik, M., Costa, R.L.B., Milhem, M., Rademaker, A.W., Prunder, B.C., Daniels, D., Rhodes, B.T., Humphreys, C., Abbinanti, S., Nye, L., Cehic, R., Polish, A., Vintilescu, C., McFarland, T., Skubitz, K., Robinson, S., Okuno, S., Van Tine, B.A.

“…Soft tissue sarcomas (STSs) overexpress vascular endothelial growth factors (VEGF) and VEGF-receptors (VEGFR) activation have been associated with tumor…”
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A phase II study of pazopanib with oral topotecan in patients with metastatic osteosarcoma by van Tine, B.A., Mohindra, N., Milhem, M., Attia, S., Robinson, S.I., Rademaker, A., Okuno, S.H., Agulnik, M.

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Molecular characterization of epithelioid sarcoma (ES) tumors derived from patients enrolled in a phase II study of tazemetostat (NCT02601950) by Daigle, S., Stacchiotti, S., Schöffski, P., Villalobos, V., Cote, G., Chugh, R., Chen, T.W.-W., Jahan, T., Loggers, E.T., Italiano, A., Gupta, A., Agulnik, M., Attia, S., Jones, R.L., van Tine, B.A., Demetri, G.D.D., Clawson, A., Roche, M., Blakemore, S., Gounder, M.

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A phase II, multicenter study of the EZH2 inhibitor tazemetostat in adults: Epithelioid sarcoma cohort (NCT02601950) by Gounder, M., Schöffski, P., Villalobos, V., Cote, G., Chugh, R., Chen, T.W.-W., Jahan, T., Loggers, E.T., Italiano, A., Gupta, A., Agulnik, M., Attia, S., Jones, R.L., van Tine, B.A., Demetri, G.D.D., Roche, M., Sapir, I., Daigle, S., Clawson, A., Stacchiotti, S.

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Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription by Ma, T, Van Tine, B A, Wei, Y, Garrett, M D, Nelson, D, Adams, P D, Wang, J, Qin, J, Chow, L T, Harper, J W

“…Cyclin E/Cdk2 acts at the G1/S-phase transition to promote the E2F transcriptional program and the initiation of DNA synthesis. To explore further how cyclin…”
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Assignment of N-acetyl-D-glucosaminidase (Mgea5) to rat chromosome 1q5 by tyramide fluorescence in situ hybridization (T-FISH): synteny between rat, mouse and human with Insulin Degradation Enzyme (IDE) by Van Tine, B A, Patterson, A J, Kudlow, J E

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19INMetabolic consequences of arginine deprivation in ASS1-deficient cancers by Van Tine, B

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Metabolic consequences of arginine deprivation in ASS1-deficient cancers by Van Tine, B.

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Mother-to-Infant Transmission of the Human Immunodeficiency Virus during Primary Infection by Van Tine, Brian A, Shaw, George M, Aldrovandi, Grace

“…To the Editor: The efficacy of antiretroviral-drug therapy in preventing mother-to-infant transmission of the human immunodeficiency virus (HIV) has led to the…”
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Localization of HuC (ELAVL3) to chromosome 19p13.2 by fluorescence in situ hybridization utilizing a novel tyramide labeling technique by VAN TINE, B. A, KNOPS, J. F, BUTLER, A, DELOUKAS, P, SHAW, G. M, KING, P. H

“…HuC is a neural-specific member of the Elav family of RNA-binding proteins. This highly conserved gene family plays a crucial role in neurogenesis, and HuC…”
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Functional Analysis of the Simian Immunodeficiency Virus Vpx Protein: Identification of Packaging Determinants and a Novel Nuclear Targeting Domain by Mahalingam, S, Van Tine, B, Santiago, M L, Gao, F, Shaw, G M, Hahn, B H

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human Papillomavirus DNA Replication Compartments in a Transient DNA Replication System by Swindle, C S, Zou, N, Van Tine, B A, Shaw, G M, Engler, J A, Chow, L T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Characterization of CFTR expression and chloride channel activity in human endothelia by Tousson, A, Van Tine, B A, Naren, A P, Shaw, G M, Schwiebert, L M

“…The cystic fibrosis transmembrane conductance regulator (CFTR) functions as a low-conductance, cAMP-regulated chloride (Cl-) channel in a variety of cell…”
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Combined xCT and mTOR Inhibition as a New Therapeutic Option for Pancreatic Adenocarcinoma by Newcomer, K., Spitzer, D., Ross, L., Caldwell, K., Vangveravong, S., Van Tine, B., Hawkins, W.

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