Search Results - "Van Saen, D"

Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate by Ntemou, E, Kadam, P, Van Saen, D, Wistuba, J, Mitchell, R T, Schlatt, S, Goossens, E

“…Abstract STUDY QUESTION Can full spermatogenesis be achieved after xenotransplantation of prepubertal primate testis tissue to the mouse, in testis or…”
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What is the best cryopreservation protocol for human testicular tissue banking? by Baert, Y., Van Saen, D., Haentjens, P., In't Veld, P., Tournaye, H., Goossens, E.

“…STUDY QUESTION Is there a better alternative to the conventional cryopreservation protocols for human testicular tissue banking? SUMMARY ANSWER Uncontrolled…”
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Meiotic activity in orthotopic xenografts derived from human postpubertal testicular tissue by Van Saen, D., Goossens, E., Bourgain, C., Ferster, A., Tournaye, H.

“…BACKGROUND Grafting of frozen-thawed testicular tissue has been suggested as a novel fertility preservation method for patients undergoing gonadotoxic…”
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Spermatogonial stem cell preservation and transplantation: from research to clinic by Goossens, E., Van Saen, D., Tournaye, H.

“…STUDY QUESTION What issues remain to be solved before fertility preservation and transplantation can be offered to prepubertal boys? SUMMARY ANSWER The main…”
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When does germ cell loss and fibrosis occur in patients with Klinefelter syndrome? by Van Saen, D, Vloeberghs, V, Gies, I, Mateizel, I, Sermon, K, De Schepper, Jean, Tournaye, H, Goossens, E

“…Abstract STUDY QUESTION When does germ cell loss and fibrosis occur in patients with Klinefelter syndrome (KS)? SUMMARY ANSWER In KS, germ cell loss is not…”
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Spermatogonial stem cell preservation and transplantation: from research to clinic by Goossens, E., Van Saen, D., Tournaye, H.

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Can pubertal boys with Klinefelter syndrome benefit from spermatogonial stem cell banking? by Van Saen, D., Gies, I., De Schepper, J., Tournaye, H., Goossens, E.

“…BACKGROUND Although early development of testes appears normal in boys with Klinefelter syndrome (KS), spermatogonial stem cell (SSC) depletion occurs in mid…”
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Failure of a combined clinical- and hormonal-based strategy to detect early spermatogenesis and retrieve spermatogonial stem cells in 47,XXY boys by single testicular biopsy by Gies, I., De Schepper, J., Van Saen, D., Anckaert, E., Goossens, E., Tournaye, H.

“…Although germ cells in boys with Klinefelter syndrome (KS) are reduced in number as early as infancy, a severe germ cell loss occurs during mid-puberty…”
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Can mesenchymal stem cells improve spermatogonial stem cell transplantation efficiency? by Kadam, P., Van Saen, D., Goossens, E.

“…Summary Improved treatments have led to an increased survival rate in cancer patients. However, in pre‐pubertal boys, these gonadotoxic treatments can result…”
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Mouse germ cells go through typical epigenetic modifications after intratesticular tissue grafting by Goossens, E., Bilgec, T., Van Saen, D., Tournaye, H.

“…BACKGROUND Since spermatogonial stem cell transplantation (SSCT) and testicular tissue grafting (TTG) may have important clinical applications, the safety of…”
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Is the protein expression window during testicular development affected in patients at risk for stem cell loss? by Van Saen, D., Pino Sánchez, J., Ferster, A., van der Werff ten Bosch, J., Tournaye, H., Goossens, E.

“…STUDY QUESTION Is the protein expression window during testicular development affected in prepubertal patients at risk for stem cell loss? SUMMARY ANSWER…”
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Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment by Hutka, Marsida, Kadam, Prashant, Van Saen, Dorien, Homer, Natalie Z M, Onofre, Jaime, Wallace, W Hamish B, Smith, Lee B, Stukenborg, Jan-Bernd, Goossens, Ellen, Mitchell, Rod T

“…Survivors of childhood cancer are at risk for long-term treatment-induced health sequelae, including gonadotoxicity and iatrogenic infertility. At present, for…”
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Mouse spermatogonial stem cells obtain morphologic and functional characteristics of hematopoietic cells in vivo by Ning, Liang, Goossens, Ellen, Geens, Mieke, Van Saen, Dorien, Van Riet, Ivan, He, Dalin, Tournaye, Herman

“…BACKGROUND The aim of this study was to explore the plasticity and transdifferentiation potential of murine spermatogonial stem cells (SSCs) into hematopoietic…”
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In search of the most efficient fertility preservation strategy for prepubertal boys by Van Saen, D

“…Fertility preservation strategies are currently being developed for boys facing spermatogonial stem cell (SSC) loss. However, it is not clear yet which…”
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P-087 Transcriptomic differences between fibrotic and non-fibrotic testicular tissue reveal possible key players in Klinefelter syndrome-related testicular fibrosis by Willems, M, Olsen, C, Caljon, B, Heremans, Y, Vloeberghs, V, De schepper, J, Tournaye, H, Van Saen, D, Goossens, E

“…Abstract Study question Which genes are differentially expressed between patients with and without testicular fibrosis? Summary answer This study revealed…”
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