Search Results - "Van Royen, M"

Cross-resistance between taxanes and new hormonal agents abiraterone and enzalutamide may affect drug sequence choices in metastatic castration-resistant prostate cancer by van Soest, R.J, van Royen, M.E, de Morrée, E.S, Moll, J.M, Teubel, W, Wiemer, E.A.C, Mathijssen, R.H.J, de Wit, R, van Weerden, W.M

“…Abstract Introduction Treatment options for patients with metastatic castration-resistant prostate cancer (mCRPC) have expanded in recent years with the…”
Get full text

Simple urine storage protocol for extracellular vesicle proteomics compatible with at-home self-sampling by Erozenci, L. A., Pham, T. V., Piersma, S. R., Dits, N. F. J., Jenster, G. W., van Royen, M. E., Moorselaar, R. J. A., Jimenez, C. R., Bijnsdorp, I. V.

“…Urinary extracellular vesicles (EVs) have gained increased interest as a biomarker source. Clinical implementation on a daily basis requires protocols that…”
Get full text

Automated spherical aberration correction in scanning confocal microscopy by Yoo, H W, van Royen, M E, van Cappellen, W A, Houtsmuller, A B, Verhaegen, M, Schitter, G

“…Mismatch between the refractive indexes of immersion media and glass coverslips introduces spherical aberrations in microscopes especially for high numerical…”
Get more information

Molecular underpinnings of enzalutamide resistance by Prekovic, S, Van den Broeck, T, Linder, S, van Royen, M E, Houtsmuller, A B, Handle, F, Joniau, S, Zwart, W, Claessens, F

“…Prostate cancer (PCa) is among the most common adult malignancies, and the second leading cause of cancer-related death in men. As PCa is hormone dependent,…”
Get full text

Multiple object tracking in molecular bioimaging by Rao-Blackwellized marginal particle filtering by Smal, I., Meijering, E., Draegestein, K., Galjart, N., Grigoriev, I., Akhmanova, A., van Royen, M.E., Houtsmuller, A.B., Niessen, W.

“…Time-lapse fluorescence microscopy imaging has rapidly evolved in the past decade and has opened new avenues for studying intracellular processes in vivo. Such…”
Get full text

Molecular underpinnings of enzalutamide resistance by Prekovic, S, van den Broeck, T, Linder, S, van Royen, M E, Houtsmuller, A B, Handle, F, Joniau, S, Zwart, W, Claessens, F

“…Prostate cancer (PCa) is among the most common adult malignancies, and the second leading cause of cancer-related death in men. As PCa is hormone dependent,…”
Get full text

Genetic and epigenetic determinants of reactivation of Mecp2 and the inactive X chromosome in neural stem cells by Mira-Bontenbal, H., Tan, B., Gontan, C., Goossens, S., Boers, R.G., Boers, J.B., Dupont, C., van Royen, M.E., IJcken, W.F.J., French, P., Bedalov, A., Gribnau, J.

“…Rett syndrome may be treated by reactivating the silent copy of Mecp2 from the inactive X chromosome in female cells. Most studies that model Mecp2…”
Get full text

Fluorescence resonance energy transfer of GFP and YFP by spectral imaging and quantitative acceptor photobleaching by DINANT, C, VAN ROYEN, M.E, VERMEULEN, W, HOUTSMULLER, A.B

“…To study protein-protein interactions by fluorescence energy transfer (FRET), the proteins of interest are tagged with either a donor or an acceptor…”
Get full text

TNF-α is involved in activating DNA fragmentation in skeletal muscle by CARBO, N, BUSQUETS, S, VAN ROYEN, M, ALVAREZ, B, LOPEZ-SORIANO, F. J, ARGILES, J. M

“…Intraperitoneal administration of 100 microg kg(-1) (body weight) of tumour necrosis factor-alpha to rats for 8 consecutive days resulted in a significant…”
Get full text

Variable loss of functional activities of androgen receptor mutants in patients with androgen insensitivity syndrome by Elfferich, P, van Royen, M E, van de Wijngaart, D J, Trapman, J, Drop, S L S, van den Akker, E L T, Lusher, S J, Bosch, R, Bunch, T, Hughes, I A, Houtsmuller, A B, Cools, M, Faradz, S M H, Bisschop, P H, Bunck, M C M, Oostdijk, W, Brüggenwirth, H T, Brinkmann, A O

“…Androgen receptor (AR) mutations in androgen insensitivity syndrome (AIS) are associated with a variety of clinical phenotypes. The aim of the present study…”
Get more information

Functional analysis of novel androgen receptor mutations in a unique cohort of Indonesian patients with a disorder of sex development by Elfferich, P, Juniarto, A Z, Dubbink, H J, van Royen, M E, Molier, M, Hoogerbrugge, J, Houtsmuller, A B, Trapman, J, Santosa, A, de Jong, F H, Drop, S L S, Faradz, S M H, Bruggenwirth, H, Brinkmann, A O

“…Mutations in the androgen receptor (AR) gene, rendering the AR protein partially or completely inactive, cause androgen insensitivity syndrome, which is a form…”
Get more information

Increased uncoupling protein-2 gene expression in brain of lipopolysaccharide-injected mice: role of tumour necrosis factor-α? by Busquets, Sı́lvia, Alvarez, Belén, Van Royen, Martin, Figueras, Maria Teresa, López-Soriano, Francisco J, Argilés, Josep M

“…In order to understand the role of brain localized uncoupling proteins, we have examined the UCP2 and BMCP-1 gene expression in mice brain in two different…”
Get full text

TNF-[alpha] is involved in activating DNA fragmentation in skeletal muscle by Carbó, N, Busquets, S, M van Royen, Alvarez, B, López-Soriano, F J, Argilés, J M

“…Intraperitoneal administration of 100 microg kg(-1) (body weight) of tumour necrosis factor-alpha to rats for 8 consecutive days resulted in a significant…”
Get full text

Patient-derived xenografts and organoids recapitulate castration-resistant prostate cancer with sustained androgen receptor signaling by Van Hemelryk, A., Tomljanovic, I., Stuurman, D., de Ridder, C.M.A., Teubel, W.J., Erkens-Schulze, S., van de Werken, H.J.G., van Royen, M., Grudniewska, M., Jenster, G.W., van Weerden, W.M.

Get full text

The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation by El Kharraz, Sarah, Dubois, Vanessa, van Royen, Martin E, Houtsmuller, Adriaan B, Pavlova, Ekatarina, Atanassova, Nina, Nguyen, Tien, Voet, Arnout, Eerlings, Roy, Handle, Florian, Prekovic, Stefan, Smeets, Elien, Moris, Lisa, Devlies, Wout, Ohlsson, Claes, Poutanen, Matti, Verstrepen, Kevin J, Carmeliet, Geert, Launonen, Kaisa-Mari, Helminen, Laura, Palvimo, Jorma J, Libert, Claude, Vanderschueren, Dirk, Helsen, Christine, Claessens, Frank

“…Whereas dimerization of the DNA-binding domain of the androgen receptor (AR) plays an evident role in recognizing bipartite response elements, the contribution…”
Get full text

Description of the dimerization surface for the ligand-binding domain of the androgen receptor and its role in transcriptional control by agonists and antagonists by Claessens, F, Nadal, M, Prekovic, S, Gallastegui, N, Helsen, C, Abella, M, Zielinska, K, Gay, M, Vilaseca, M, Taules, M, Houtsmuller, A, Van Royen, M, Fuentes-Prior, P, Estebanez-Perpina, E

Get full text

The divergent effects of tumour necrosis factor-alpha on skeletal muscle: implications in wasting by Argilés, J M, Alvarez, B, Carbó, N, Busquets, S, Van Royen, M, López-Soriano, F J

“…Tumour necrosis factor-alpha (TNF) is a pleiotropic cytokine that can have effects on many cell types, including skeletal muscle, the most abundant tissue…”
Get more information

The power of imaging to understand extracellular vesicle biology in vivo by Verweij, Frederik J., Balaj, Leonora, Boulanger, Chantal M., Carter, David R. F., Compeer, Ewoud B., D’Angelo, Gisela, El Andaloussi, Samir, Goetz, Jacky G., Gross, Julia Christina, Hyenne, Vincent, Krämer-Albers, Eva-Maria, Lai, Charles P., Loyer, Xavier, Marki, Alex, Momma, Stefan, Nolte-‘t Hoen, Esther N. M., Pegtel, D. Michiel, Peinado, Hector, Raposo, Graça, Rilla, Kirsi, Tahara, Hidetoshi, Théry, Clotilde, van Royen, Martin E., Vandenbroucke, Roosmarijn E., Wehman, Ann M., Witwer, Kenneth, Wu, Zhiwei, Wubbolts, Richard, van Niel, Guillaume

“…Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every cell type. EVs have diverse biological activities, ranging from…”
Get full text

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines by Théry, Clotilde, Witwer, Kenneth W, Aikawa, Elena, Andriantsitohaina, Ramaroson, Baharvand, Hossein, Bauer, Natalie N, Baxter, Amy A, Beckham, Carla, Bielska, Ewa, Boireau, Wilfrid, Bongiovanni, Antonella, Brisson, Alain, Broekman, Marike LD, Bryl-Górecka, Paulina, Buch, Shilpa, Bussolati, Benedetta, Caruso, Sarah, Clayton, Aled, Cocucci, Emanuele, de Candia, Paola, Demaret, Tanguy, Dourado, Mauricio R, Falcón-Pérez, Juan M, Försönits, András, Frelet-Barrand, Annie, Fuhrmann, Gregor, Gabrielsson, Susanne, Gámez-Valero, Ana, Gaudin, Raphael, Handberg, Aase, Hegyesi, Hargita, Hendrix, An, Hill, Andrew F, Inal, Jameel M, Ivanova, Alena, Jackson, Hannah K, Jayachandran, Muthuvel, Jiang, Lanzhou, Kalluri, Raghu, Kaur, Sukhbir, Kierulf, Peter, Kim, Kwang Pyo, Krasemann, Susanne, Kurochkin, Igor V, Langevin, Scott M, Lázaro-Ibáñez, Elisa, Lee, Yi Xin Fiona, Libregts, Sten F, Linē, Aija, Linnemannstöns, Karen, Lombard, Catherine A, Lukomska, Barbara, Marcilla, Antonio, Mathivanan, Suresh, McVey, Mark J, Mertens, Inge, Morhayim, Jess, Mullier, François, Nawaz, Muhammad, Nimrichter, Leonardo, Noren Hooten, Nicole, Olivier, Martin, Ortiz, Luis A, Ostrowski, Matias, Pegtel, D. Michiel, Perut, Francesca, Polakovicova, Iva, Pulliam, Lynn, Regev-Rudzki, Neta, Rouschop, Kasper MA, Rughetti, Aurelia, Saá, Paula, Saul, Meike J, Schøyen, Tine Hiorth, Shahaj, Eriomina, Sharma, Shivani, Shekari, Faezeh, Siljander, Pia R-M, Skowronek, Agata, Soares, Rodrigo Pedro, Stoorvogel, Willem, Stott, Shannon L, Tixeira, Rochelle, Toh, Wei Seong, Tomasini, Richard, van Herwijnen, Martijn JC, van Niel, Guillaume, van Wijnen, Andre J, Vasconcelos, M Helena, Veit, Tiago D, Viñas, Jose L, Visnovitz, Tamás, Wehman, Ann M, Weiss, Daniel J, Wheelock, Asa M, Xagorari, Angeliki, Xander, Patricia, Zhang, Jian-ye, Zheutlin, Alexander R, Zickler, Antje M

“…The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular…”
Get full text

Evaluation of Endpoints in Ischemia Reperfusion Injury by CMR in an in vivo Rat Model of Acute Myocardial Infarction by Kuster, Carolien, Konijnenberg, Lara, Veltien, Andor, van Reijmersdal, Vince, van Royen, Niels, Nijveldt, Robin

Get full text