Search Results - "Van Rooyen, Jason"

miR-146a and miR-155 Delineate a MicroRNA Fingerprint Associated with Toxoplasma Persistence in the Host Brain by Cannella, Dominique, Brenier-Pinchart, Marie-Pierre, Braun, Laurence, van Rooyen, Jason M., Bougdour, Alexandre, Bastien, Olivier, Behnke, Michael S., Curt, Rose-Laurence, Curt, Aurélie, Saeij, Jeroen P.J., Sibley, L. David, Pelloux, Hervé, Hakimi, Mohamed-Ali

“…microRNAs were recently found to be regulators of the host response to infection by apicomplexan parasites. In this study, we identified two immunomodulatory…”
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Crystal Structure of Type III Glutamine Synthetase: Surprising Reversal of the Inter-Ring Interface by van Rooyen, Jason M., Abratt, Valerie R., Belrhali, Hassan, Sewell, Trevor

“…Glutamine synthetases are ubiquitous, homo-oligomeric enzymes essential for nitrogen metabolism. Unlike types I and II, which are well described both…”
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Assembly of the novel five-component apicomplexan multi-aminoacyl-tRNA synthetase complex is driven by the hybrid scaffold protein Tg-p43 by van Rooyen, Jason M, Murat, Jean-Benjamin, Hammoudi, Pierre-Mehdi, Kieffer-Jaquinod, Sylvie, Coute, Yohann, Sharma, Amit, Pelloux, Hervé, Belrhali, Hassan, Hakimi, Mohamed-Ali

“…In Toxoplasma gondii, as in other eukaryotes, a subset of the amino-acyl-tRNA synthetases are arranged into an abundant cytoplasmic multi-aminoacyl-tRNA…”
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1,3-Bis(2-methoxyphenyl)thiourea by Rooyen, Jason van, Betz, Richard, Brecht, Bernardus J. A. M. van

“…In the title compound, C15H16N2O2S, the N–C(=S) bond lengths are indicative of the presence of amide-type resonance. The dihedral angles between the…”
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Structural analysis of malaria-parasite lysyl-tRNA synthetase provides a platform for drug development by Khan, Sameena, Garg, Ankur, Camacho, Noelia, Van Rooyen, Jason, Kumar Pole, Anil, Belrhali, Hassan, Ribas de Pouplana, Lluis, Sharma, Vinay, Sharma, Amit

“…Aminoacyl‐tRNA synthetases are essential enzymes that transmit information from the genetic code to proteins in cells and are targets for antipathogen drug…”
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Recombinant expression, purification, and crystallization of the glutaminyl-tRNA synthetase from Toxoplasma gondii by van Rooyen, Jason M., Hakimi, Mohamed-Ali, Belrhali, Hassan

“…•Recombinant T. gondii QRS is highly expressed as an active enzyme in E. coli.•Full-length QRS is prone to degradation into component domains.•Component…”
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A Workflow for Protein Structure Determination From Thin Crystal Lamella by Micro-Electron Diffraction by Beale, Emma V, Waterman, David G, Hecksel, Corey, van Rooyen, Jason, Gilchrist, James B, Parkhurst, James M, de Haas, Felix, Buijsse, Bart, Evans, Gwyndaf, Zhang, Peijun

“…MicroED has recently emerged as a powerful method for the analysis of biological structures at atomic resolution. This technique has been largely limited to…”
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Three-dimensional Structure of a Type III Glutamine Synthetase by Single-particle Reconstruction by van Rooyen, Jason M., Abratt, Valerie R., Sewell, B. Trevor

“…GlnN, the type III glutamine synthetase (GSIII) from the medically important, anaerobic, opportunistic pathogen Bacteroides fragilis, has 82.8 kDa subunits…”
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Streptomyces africanus sp. nov., a novel streptomycete with blue aerial mycelium by Meyers, Paul R, Goodwin, Candice M, Bennett, Jessica A, Aken, Bronwen L, Price, Claire E, van Rooyen, Jason M

“…Department of Molecular and Cell Biology, University of Cape Town, Private Bag 1, Rondebosch, 7701, Cape Town, South Africa Correspondence Paul R. Meyers…”
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Proteolysis of the type III glutamine synthetase from Bacteroides fragilis causes expedient crystal-packing rearrangements by van Rooyen, Jason, Belrhali, Hassan, Abratt, Valarie, Sewell, B. Trevor

“…This work details the intentional modifications that led to the first structure of a type III glutamine synthetase enzyme (GSIII). This approach followed the…”
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Streptomyces africanus sp. nov., a novel streptomycete with blue aerial mycelium by Meyers, Paul R., Goodwin, Candice M., Bennett, Jessica A., Aken, Bronwen L., Price, Claire E., van Rooyen, Jason M.

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Synthesis of ferrocenylphenyl derivatives including biphenylferrocenes, arylferrocenylphenyl ethers and arylferrocenylphenyl amines by Imrie, Christopher, Engelbrecht, Pieter, Loubser, Christa, McCleland, Cedric W, Nyamori, Vincent O, Bogardi, Robert, Levendis, Demetrius C, Tolom, Nomfuneko, van Rooyen, Jason, Williams, Nadia

“…The preparation of a series of substituted biphenylferrocenes via a modified Suzuki reaction between 4-bromophenylferrocene and substituted phenylboronic acids…”
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Proteolysis of the type III glutamine synthetase from Bacteroides fragilis causes expedient crystalapacking rearrangements by van Rooyen, Jason, Belrhali, Hassan, Abratt, Valarie, Sewell, BTrevor

“…This work details the intentional modifications that led to the first structure of a type III glutamine synthetase enzyme (GSIII). This approach followed the…”
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1,3-Bis(2-meth-oxy-phen-yl)thio-urea by van Rooyen, Jason, Betz, Richard, van Brecht, Bernardus J A M

“…In the title compound, C(15)H(16)N(2)O(2)S, the N-C(=S) bond lengths are indicative of the presence of amide-type resonance. The dihedral angles between the…”
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