Search Results - "Van Rietschoten, Jurphaas"
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Cobatoxin 1 from Centruroides noxius scorpion venom: chemical synthesis, three-dimensional structure in solution, pharmacology and docking on K+ channels
Published in Biochemical journal (01-01-2004)“…CoTX1 (cobatoxin 1) is a 32-residue toxin with three disulphide bridges that has been isolated from the venom of the Mexican scorpion Centruroides noxius…”
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Enzymatic N-glycosylation of synthetic ASN-X-THR containing peptides
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3
The kaliotoxin family enlarged. Purification, characterization, and precursor nucleotide sequence of KTX2 from Androctonus australis venom
Published in The Journal of biological chemistry (30-12-1994)“…Kaliotoxin (KTX) has been originally described as an inhibitor of the intermediate conductance Ca(2+)-activated K+ channel (Crest, M., Jacquet, G., Gola, M.,…”
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First chemical synthesis of a scorpion α-toxin affecting sodium channels: The Aah I toxin of Androctonus australis hector
Published in Journal of peptide science (01-11-2004)“…Aah I is a 63‐residue α‐toxin isolated from the venom of the Buthidae scorpion Androctonus australis hector, which is considered to be the most dangerous…”
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Liposomal encapsulation enhances antiviral efficacy of SPC3 against human immunodeficiency virus type-1 infection in human lymphocytes
Published in Antiviral research (01-06-2002)“…Because encapsulation of antiviral drugs in liposomes resulted generally in improved activity against retroviral replication in vivo, the antiviral effects of…”
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6
A New Conotoxin Affecting Sodium Current Inactivation Interacts with the δ-Conotoxin Receptor Site (∗)
Published in The Journal of biological chemistry (20-01-1995)“…We describe a new peptide conotoxin affecting sodium current inactivation, that competes on binding with δ-conotoxin TxVIA (δTxVIA). The amino acid sequence of…”
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7
First chemical synthesis of a scorpion a-toxin affecting sodium channels: The Aah I toxin of Androctonus australis hector
Published in Journal of peptide science (01-11-2004)“…Aah I is a 63-residue -toxin isolated from the venom of the Buthidae scorpion Androctonus australis hector, which is considered to be the most dangerous…”
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Synthesis and characterization of kaliotoxin. Is the 26-32 sequence essential for potassium channel recognition?
Published in The Journal of biological chemistry (15-12-1993)“…Kaliotoxin (KTX), a scorpion toxin characterized as a 37-residue inhibitor of the neuronal high conductance Ca(2+)-activated K+ channels (KCa channels), has…”
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Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides
Published in Journal of Virology (01-05-1994)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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SPC3, a Synthetic Peptide Derived from the V3 Domain of Human Immunodeficiency Virus Type 1 (HIV-1) gp120, Inhibits HIV-1 Entry into CD4+and CD4-Cells by Two Distinct Mechanisms
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-1995)“…The third variable region (V3 loop) of gp120, the HIV-1 surface envelope glycoprotein, plays a key role in HIV-1 infection and pathogenesis. Recently, we…”
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Chemical Synthesis and Characterization of Maurotoxin, a Short Scorpion Toxin with four Disulfide Bridges that Acts on K+ Channels
Published in European journal of biochemistry (15-12-1996)“…Maurotoxin is a toxin isolated from the venom of the Tunisian chactoid scorpion Scorpio maurus. It is a 34‐amino‐acid peptide cross‐linked by four disulfide…”
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Multibranched V3 peptides inhibit human immunodeficiency virus infection in human lymphocytes and macrophages
Published in Journal of Virology (01-09-1994)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
3D structure of kaliotoxin: is residue 34 a key for channel selectivity?
Published in Journal of peptide science (01-07-1997)“…Kaliotoxin (KTX) is a natural peptide blocker of voltage‐dependent K+ channels. The 3D structure of a truncated analogue of KTX (Fernández et al. (1994)…”
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14
Activating region of HIV-1 Tat protein: vacuum UV circular dichroism and energy minimization
Published in Biochemistry (Easton) (18-06-1991)“…Tat protein is a trans-acting transcriptional activator of the human immunodeficiency virus type 1 and is essential for viral transcription. By homology with…”
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Anti-HIV Activity of Multibranched Peptide Constructs Derived either from the Cleavage Sequence or from the Transmembrane Domain (gp41) of the Human Immunodeficiency Virus Type 1 Envelope
Published in Virology (New York, N.Y.) (15-09-1996)“…Multibranched peptides (SPCs) derived either from the fusion protein (gp41) sequence or from the cleavage sequence of the human immunodeficiency virus type 1…”
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Characterization of an electrogenic sodium/glucose cotransporter in a human colon epithelial cell line
Published in Journal of cellular physiology (01-04-1995)“…In this study, we have characterized the Na/glucose transporter in polarized monolayers formed by the clonal human colon carcinoma cell line HT-29-D4. Isotopic…”
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Lethal neurotoxicity in mice of the basic domains of HIV and SIV Rev proteins Study of these regions by circular dichroism
Published in FEBS letters (02-09-1991)“…We have recently reported a basic domain-mediated neurotoxic activity of HIV-1 Tat [1991, J. Virol. 65, 961–965]. Here we have tested the neurotoxicity in vivo…”
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Correlation of Antiviral Activity with .beta.-Turn Types for V3 Synthetic Multibranched Peptides from HIV-1 gp120
Published in Biochemistry (Easton) (04-07-1995)“…SPC3 is a synthetic multibranched peptide containing eight HIV-1 gp120 V3 loop GPGRAF motifs. SPC3 inhibits HIV-1 infection in human lymphocytes and…”
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A New Conotoxin Affecting Sodium Current Inactivation Interacts with the -Conotoxin Receptor Site
Published in The Journal of biological chemistry (20-01-1995)“…We describe a new peptide conotoxin affecting sodium current inactivation, that competes on binding with -conotoxin TxVIA ( TxVIA). The amino acid sequence of…”
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20
Cytotoxic effect on lymphocytes of Tat from human immunodeficiency virus (HIV-1)
Published in FEBS letters (15-03-1993)“…The human immunodeficiency virus type 1 (HIV-1) genome codes for trans-activator Tat, an 86-residue protein whose expression is critical for viral replication…”
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