Search Results - "Van Nuffel, An MT"

ReDO_DB: the repurposing drugs in oncology database by Pantziarka, Pan, Verbaanderd, Ciska, Sukhatme, Vidula, Rica Capistrano, I, Crispino, Sergio, Gyawali, Bishal, Rooman, Ilse, Van Nuffel, An Mt, Meheus, Lydie, Sukhatme, Vikas P, Bouche, Gauthier

“…Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity…”
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Repurposing Drugs in Oncology (ReDO)-clarithromycin as an anti-cancer agent by Van Nuffel, An Mt, Sukhatme, Vidula, Pantziarka, Pan, Meheus, Lydie, Sukhatme, Vikas P, Bouche, Gauthier

“…Clarithromycin (CAM) is a well-known macrolide antibiotic available as a generic drug. CAM is traditionally used for many types of bacterial infections,…”
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Design of an Optimized Wilms’ Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo by Benteyn, Daphné, Anguille, Sébastien, Van Lint, Sandra, Heirman, Carlo, Van Nuffel, An MT, Corthals, Jurgen, Ochsenreither, Sebastian, Waelput, Wim, Van Beneden, Katrien, Breckpot, Karine, Van Tendeloo, Viggo, Thielemans, Kris, Bonehill, Aude

“…Tumor antigen–encoding mRNA for dendritic cell (DC)-based vaccination has gained increasing popularity in recent years. Within this context, two main…”
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Enhancing the T-cell Stimulatory Capacity of Human Dendritic Cells by Co-electroporation With CD40L, CD70 and Constitutively Active TLR4 Encoding mRNA by Bonehill, Aude, Tuyaerts, Sandra, Van Nuffel, An MT, Heirman, Carlo, Bos, Tomas J, Fostier, Karel, Neyns, Bart, Thielemans, Kris

“…The effectiveness of the dendritic cell (DC) vaccination protocols that are currently in use could be improved by providing the DCs with a more potent…”
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Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4+ and CD8+ T Cells in Melanoma Patients by Van Nuffel, An MT, Benteyn, Daphné, Wilgenhof, Sofie, Pierret, Lauranne, Corthals, Jurgen, Heirman, Carlo, van der Bruggen, Pierre, Coulie, Pierre G, Neyns, Bart, Thielemans, Kris, Bonehill, Aude

“…It is generally thought that dendritic cells (DCs) loaded with full-length tumor antigen could improve immunotherapy by stimulating broad T-cell responses and…”
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Modulation of regulatory T cell function by monocyte-derived dendritic cells matured through electroporation with mRNA encoding CD40 ligand, constitutively active TLR4, and CD70 by Pen, Joeri J, De Keersmaecker, Brenda, Maenhout, Sarah K, Van Nuffel, An M T, Heirman, Carlo, Corthals, Jurgen, Escors, David, Bonehill, Aude, Thielemans, Kris, Breckpot, Karine, Aerts, Joeri L

“…Regulatory T cells (Tregs) counteract anticancer immune responses through a number of mechanisms, limiting dendritic cell (DC)-based anticancer immunotherapy…”
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Characterization of CD8+ T-Cell Responses in the Peripheral Blood and Skin Injection Sites of Melanoma Patients Treated with mRNA Electroporated Autologous Dendritic Cells (TriMixDC-MEL) by Bonehill, Aude, Neyns, Bart, Heirman, Carlo, Corthals, Jurgen, Wilgenhof, Sofie, Van Nuffel, An M. T., Benteyn, Daphné, Thielemans, Kris

“…Treatment of melanoma patients with mRNA electroporated dendritic cells (TriMixDC-MEL) stimulates T-cell responses against the presented tumor-associated…”
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Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4 super(+) and CD8 super(+) T Cells in Melanoma Patients by Van Nuffel, An MT, Benteyn, Daphne, Wilgenhof, Sofie, Pierret, Lauranne, Corthals, Jurgen, Heirman, Carlo, van der Bruggen, Pierre, Coulie, Pierre G, Neyns, Bart, Thielemans, Kris, Bonehill, Aude

“…It is generally thought that dendritic cells (DCs) loaded with full-length tumor antigen could improve immunotherapy by stimulating broad T-cell responses and…”
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