Search Results - "Van Ly, David"

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  1. 1

    Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress by Lamm, Noa, Read, Mark N., Nobis, Max, Van Ly, David, Page, Scott G., Masamsetti, V. Pragathi, Timpson, Paul, Biro, Maté, Cesare, Anthony J.

    Published in Nature cell biology (01-12-2020)
    “…Filamentous actin (F-actin) provides cells with mechanical support and promotes the mobility of intracellular structures. Although F-actin is traditionally…”
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    Journal Article
  2. 2

    Telomere Loop Dynamics in Chromosome End Protection by Van Ly, David, Low, Ronnie Ren Jie, Frölich, Sonja, Bartolec, Tara K., Kafer, Georgia R., Pickett, Hilda A., Gaus, Katharina, Cesare, Anthony J.

    Published in Molecular cell (16-08-2018)
    “…Telomeres regulate DNA damage response (DDR) and DNA repair activity at chromosome ends. How telomere macromolecular structure contributes to ATM regulation…”
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  3. 3

    CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle by Sarek, Grzegorz, Kotsantis, Panagiotis, Ruis, Phil, Van Ly, David, Margalef, Pol, Borel, Valerie, Zheng, Xiao-Feng, Flynn, Helen R., Snijders, Ambrosius P., Chowdhury, Dipanjan, Cesare, Anthony J., Boulton, Simon J.

    Published in Nature (London) (01-11-2019)
    “…The protection of telomere ends by the shelterin complex prevents DNA damage signalling and promiscuous repair at chromosome ends. Evidence suggests that the…”
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    Journal Article
  4. 4

    Differential neutrophil activation in viral infections: Enhanced TLR-7/8-mediated CXCL8 release in asthma by Tang, Francesca S.M., Van Ly, David, Spann, Kirsten, Reading, Patrick C., Burgess, Janette K., Hartl, Dominik, Baines, Katherine J., Oliver, Brian G.

    Published in Respirology (Carlton, Vic.) (01-01-2016)
    “…Background and objective Respiratory viral infections are a major cause of asthma exacerbations. Neutrophils accumulate in the airways and the mechanisms that…”
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    Journal Article
  5. 5

    Characterising the mechanism of airway smooth muscle β2 adrenoceptor desensitization by rhinovirus infected bronchial epithelial cells by Van Ly, David, Faiz, Alen, Jenkins, Christine, Crossett, Ben, Black, Judith L, McParland, Brent, Burgess, Janette K, Oliver, Brian G G

    Published in PloS one (15-02-2013)
    “…Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to β2…”
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    Journal Article
  6. 6

    Lipid-Producing Ciliochoroidal Melanoma with Expression of HMG-CoA Reductase by Van Ly, David, Wang, Duo, Conway, Robert Max, Giblin, Michael, Liang, Sharron, Lukeis, Robyn, Lim, Li-Anne, Hesson, Luke, Cherepanoff, Svetlana

    Published in Ocular oncology and pathology (01-12-2020)
    “…Uveal melanoma (UM) is the commonest primary intraocular malignancy in adults. There is limited published data on lipid production in UM. Here, we describe the…”
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    Journal Article
  7. 7

    Effects of β_2 Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts by Van Ly, David, King, Nicholas J.C., Moir, Lyn M., Burgess, Janette K., Black, Judith L., Oliver, Brian G.

    Published in Journal of Allergy (01-12-2011)
    “…Rhinovirus-(RV-) induced asthma exacerbations account for high asthma-related health costs and morbidity in Australia. The cellular mechanism underlying this…”
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    Journal Article
  8. 8

    TRF2-independent chromosome end protection during pluripotency by Ruis, Phil, Van Ly, David, Borel, Valerie, Kafer, Georgia R., McCarthy, Afshan, Howell, Steven, Blassberg, Robert, Snijders, Ambrosius P., Briscoe, James, Niakan, Kathy K., Marzec, Paulina, Cesare, Anthony J., Boulton, Simon J.

    Published in Nature (London) (07-01-2021)
    “…Mammalian telomeres protect chromosome ends from aberrant DNA repair 1 . TRF2, a component of the telomere-specific shelterin protein complex, facilitates end…”
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    Journal Article
  9. 9

    Differential neutrophil activation in viral infections: Enhanced TLR ‐7/8‐mediated CXCL 8 release in asthma by Tang, Francesca S.M., Van Ly, David, Spann, Kirsten, Reading, Patrick C., Burgess, Janette K., Hartl, Dominik, Baines, Katherine J., Oliver, Brian G.

    Published in Respirology (Carlton, Vic.) (01-01-2016)
    “…Abstract Background and objective Respiratory viral infections are a major cause of asthma exacerbations. Neutrophils accumulate in the airways and the…”
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    Journal Article
  10. 10

    Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle by Van Ly, David, De Pedro, Monique, James, Peter, Morgan, Lucy, Black, Judith L, Burgess, Janette K, Oliver, Brian G G

    Published in Respiratory research (15-11-2013)
    “…Virus-induced exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are a significant health burden and occur even in those receiving the best current…”
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    Journal Article
  11. 11

    Characterising the Mechanism of Airway Smooth Muscle [beta].sub.2 Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells by Van Ly, David, Faiz, Alen, Jenkins, Christine, Crossett, Ben, Black, Judith L, McParland, Brent, Burgess, Janette K, Oliver, Brian G. G

    Published in PloS one (15-02-2013)
    “…Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to…”
    Get full text
    Journal Article
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  14. 14

    Effects of β(2) Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts by Van Ly, David, King, Nicholas J C, Moir, Lyn M, Burgess, Janette K, Black, Judith L, Oliver, Brian G

    Published in Journal of allergy (2011)
    “…Rhinovirus-(RV-) induced asthma exacerbations account for high asthma-related health costs and morbidity in Australia. The cellular mechanism underlying this…”
    Get full text
    Journal Article
  15. 15

    Effects of β2 Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts by Oliver, Brian G., Black, Judith L., Burgess, Janette K., Moir, Lyn M., King, Nicholas J.C., Van Ly, David

    Published in Journal of allergy (2011)
    “…Rhinovirus-(RV-) induced asthma exacerbations account for high asthma-related health costs and morbidity in Australia. The cellular mechanism underlying this…”
    Get full text
    Journal Article
  16. 16

    Do we really need to keep redesigning β2-agonists for the management of asthma? by Van Ly, David, Oliver, Brian G G

    Published in Current drug delivery (2015)
    “…There is an enormous drive to refine therapeutic designs and delivery systems, but in this review we ask if this is always the right direction? We choose to…”
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    Journal Article
  17. 17