Search Results - "Van Loon, Jack J.W.A."

Plant cell proliferation and growth are altered by microgravity conditions in spaceflight by Matía, Isabel, González-Camacho, Fernando, Herranz, Raúl, Kiss, John Z., Gasset, Gilbert, van Loon, Jack J.W.A., Marco, Roberto, Javier Medina, Francisco

“…Seeds of Arabidopsis thaliana were sent to space and germinated in orbit. Seedlings grew for 4 d and were then fixed in-flight with paraformaldehyde. The…”
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The interaction between nanoscale surface features and mechanical loading and its effect on osteoblast-like cells behavior by Prodanov, Ljupcho, te Riet, Joost, Lamers, Edwin, Domanski, Maciej, Luttge, Regina, van Loon, Jack J.W.A, Jansen, John A, Walboomers, X. Frank

“…Abstract Osteoblasts respond to mechanical stimulation by changing morphology, gene expression and matrix mineralization. Introducing surface topography on…”
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Dynamic shear stress in parallel-plate flow chambers by Bacabac, Rommel G., Smit, Theo H., Cowin, Stephen C., Van Loon, Jack J.W.A., Nieuwstadt, Frans T.M., Heethaar, Rob, Klein-Nulend, Jenneke

“…An in vitro model using a parallel-plate fluid flow chamber is supposed to simulate in vivo fluid shear stresses on various cell types exposed to dynamic fluid…”
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Nitric oxide production by bone cells is fluid shear stress rate dependent by Bacabac, Rommel G, Smit, Theo H, Mullender, Margriet G, Dijcks, Saskia J, Van Loon, Jack J.W.A, Klein-Nulend, Jenneke

“…Shear stress due to mechanical loading-induced flow of interstitial fluid through the lacuno-canalicular network is a likely signal for bone cell adaptive…”
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Comparison of Microgravity Analogs to Spaceflight in Studies of Plant Growth and Development by Kiss, John Z, Wolverton, Chris, Wyatt, Sarah E, Hasenstein, Karl H, van Loon, Jack J W A

“…Life on Earth has evolved under the influence of gravity. This force has played an important role in shaping development and morphology from the molecular…”
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Simulated microgravity, Mars gravity, and 2g hypergravity affect cell cycle regulation, ribosome biogenesis, and epigenetics in Arabidopsis cell cultures by Kamal, Khaled Y., Herranz, Raúl, van Loon, Jack J. W. A., Medina, F. Javier

“…Gravity is the only component of Earth environment that remained constant throughout the entire process of biological evolution. However, it is still unclear…”
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Measuring Intracellular Viscosity in Conditions of Hypergravity by Woodcock, Emma M., Girvan, Paul, Eckert, Julia, Lopez-Duarte, Ismael, Kubánková, Markéta, van Loon, Jack J.W.A., Brooks, Nicholas J., Kuimova, Marina K.

“…Gravity-sensitive cellular responses are regularly observed in both specialized and nonspecialized cells. One potential mechanism for this sensitivity is a…”
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Some history and use of the random positioning machine, RPM, in gravity related research by van Loon, Jack J.W.A.

“…The first experiments using machines and instruments to manipulate gravity and thus learn about its impact to this force onto living systems were performed by…”
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Degassing of a decompressed flowing liquid under hypergravity conditions by Oikonomidou, Ourania, Evgenidis, Sotiris P., Schwarz, Christian J., van Loon, Jack J.W.A., Kostoglou, Margaritis, Karapantsios, Thodoris D.

“…•Bubbles buoyant velocity increases with hypergravity and so their residence time decreases.•Hypergravity decreases volumetric fraction of degassing bubbles…”
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Towards human exploration of space: the THESEUS review series on muscle and bone research priorities by Lang, Thomas, Van Loon, Jack J.W.A., Bloomfield, Susan, Vico, Laurence, Chopard, Angele, Rittweger, Joern, Kyparos, Antonios, Blottner, Dieter, Vuori, Ilkka, Gerzer, Rupert, Cavanagh, Peter R.

“…Without effective countermeasures, the musculoskeletal system is altered by the microgravity environment of long-duration spaceflight, resulting in atrophy of…”
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Centrifuges for Microgravity Simulation. The Reduced Gravity Paradigm by van Loon, Jack J. W. A.

“…Due to the cumbersome nature of performing real microgravity - spaceflight research scientists have been searching for alternatives to perform simulated…”
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Transcriptomic Analysis of Planarians under Simulated Microgravity or 8 g Demonstrates That Alteration of Gravity Induces Genomic and Cellular Alterations That Could Facilitate Tumoral Transformation by de Sousa, Nídia, Rodriguez-Esteban, Gustavo, Colagè, Ivan, D'Ambrosio, Paolo, van Loon, Jack J W A, Saló, Emili, Adell, Teresa, Auletta, Gennaro

“…The possibility of humans to live outside of Earth on another planet has attracted the attention of numerous scientists around the world. One of the greatest…”
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Invited review article: Advanced light microscopy for biological space research by De Vos, Winnok H, Beghuin, Didier, Schwarz, Christian J, Jones, David B, van Loon, Jack J W A, Bereiter-Hahn, Juergen, Stelzer, Ernst H K

“…As commercial space flights have become feasible and long-term extraterrestrial missions are planned, it is imperative that the impact of space travel and the…”
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Bone cell responses to high-frequency vibration stress: does the nucleus oscillate within the cytoplasm? by Bacabac, Rommel G, Smit, Theo H, Loon, Jack J.W.A. Van, Doulabi, Behrouz Zandieh, Helder, Marco, Klein-Nulend, Jenneke

“…Mechanosensing by cells directs changes in bone mass and structure in response to the challenges of mechanical loading. Low-amplitude, high-frequency loading…”
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Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome by Herranz, Raul, Benguria, Alberto, Lavan, David A, Lopez-Vidriero, Irene, Gasset, Gilbert, Javier Medina, F, Loon, Jack J.W.A. van, Marco, Roberto

“…Genome-wide transcriptional profiling shows that reducing gravity levels during Drosophila metamorphosis in the International Space Station (ISS) causes…”
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Planarians Sense Simulated Microgravity and Hypergravity by Auletta, Gennaro, van Loon, Jack, Saló, Emili, Adell, Teresa

“…Planarians are flatworms, which belong to the phylum Platyhelminthes. They have been a classical subject of study due to their amazing regenerative ability,…”
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Spiculous skeleton formation in the freshwater sponge Ephydatia fluviatilis under hypergravity conditions by Bart, Martijn C, de Vet, Sebastiaan J, de Bakker, Didier M, Alexander, Brittany E, van Oevelen, Dick, van Loon, E Emiel, van Loon, Jack J W A, de Goeij, Jasper M

“…Successful dispersal of freshwater sponges depends on the formation of dormant sponge bodies (gemmules) under adverse conditions. Gemmule formation allows the…”
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A Comparison of Torque Forces Used to Apply Intermaxillary Fixation Screws by Bins, Arjan, DDS, Baart, Jacques A., DDS, Forouzanfar, Tymour, DDS, MD, PhD, van Loon, Jack J.W.A., MSc, PhD

“…Purpose When establishing intermaxillary fixation (IMF) using bone screws, fracture of a screw is a potential complication. This study was conducted to…”
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Role of Mechanical Properties of Cell Mediated Vesicles in Membrane Fusion by Vorselen, Daan, Roos, Wouter H., van Loon, Jack J.W.A., Wuite, Gijs J.L.

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Substrate nanotexture and hypergravity through centrifugation enhance initial osteoblastogenesis by Prodanov, Ljupcho, van Loon, Jack J W A, te Riet, Joost, Jansen, John A, Walboomers, X Frank

“…Mimicking the structural nanomolecular extracellular matrix with synthetically designed nanosized materials is a relatively new approach, which can be applied…”
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