Search Results - "Van Kleef, Mirinda"

Identification of T cell and linear B cell epitopes on African horse sickness virus serotype 4 proteins VP1-1, VP2, VP4, VP7 and NS3 by Faber, Erika, van Schalkwyk, Antoinette, Ivy Tshilwane, Selaelo, Van Kleef, Mirinda, Pretorius, Alri

“…•AHSV4 VP1, -2, -4, -7 and NS3 contain regions with CD8+ T cell epitopes.•Overlapping peptides spanning these AHSV4 proteins were synthesized.•Recall immune…”
Get full text

Virulent African horse sickness virus serotype 4 interferes with the innate immune response in horse peripheral blood mononuclear cells in vitro by Faber, Erika, Tshilwane, Selaelo Ivy, Kleef, Mirinda Van, Pretorius, Alri

“…African horse sickness (AHS) is caused by African horse sickness virus (AHSV), a double stranded RNA (dsRNA) virus of the genus Orbivirus, family Reoviridae…”
Get full text

Editorial: Immune transcriptome sequencing reveals secrets of veterinary infectious diseases by van Kleef, Mirinda, Pretorius, Alri

Get full text

Th1 and Th2 epitopes of Cowdria polymorphic gene 1 of Ehrlichia ruminantium by Ngoepe, Tlou A, Pretorius, Alri, Steyn, Helena C, Van Kleef, Mirinda

“…Cowdria polymorphic gene 1 (cpg1, Erum2510, ERUM_RS01380) has been shown to induce 30% and 100% protection in sheep immunised by deoxyribonucleic acid (DNA)…”
Get full text

Transcriptomic analysis of Ehrlichia ruminantium during the developmental stages in bovine and tick cell culture by Tjale, Mabotse A., Pretorius, Alri, Josemans, Antoinette, Kleef, Mirinda Van, Liebenberg, Junita

“…The use of bioinformatics tools to search for possible vaccine candidates has been successful in recent years. In an attempt to search for additional vaccine…”
Get full text

Cellular immune responses induced in vitro by Ehrlichia ruminantium secreted proteins and identification of vaccine candidate peptides by Thema, Nontobeko, Pretorius, Alri, Tshilwane, Selaelo I, Liebenberg, Junita, Steyn, Helena, Van Kleef, Mirinda

“…Secreted proteins are reported to induce cell-mediated immunity characterised by the production of interferon-gamma (IFN)-γ. In this study three open reading…”
Get full text

The impact of Escherichia coli contamination products present in recombinant African horse sickness virus serotype 4 proteins on the innate and humoral immune responses by Faber, Erika, Tshilwane, Selaelo Ivy, Van Kleef, Mirinda, Pretorius, Alri

“…Transcriptome analysis was used to characterise the in vitro primary and secondary immune responses induced in horse peripheral blood mononuclear cells (PBMC)…”
Get full text

Apoptosis versus survival of African horse sickness virus serotype 4-infected horse peripheral blood mononuclear cells by Faber, Erika, Tshilwane, Selaelo Ivy, Van Kleef, Mirinda, Pretorius, Alri

“…•Apoptosis is a major host defense mechanism to limit viral replication.•Virulent (secondary response) and attenuated AHSV4-infected PBMC were killed.•Viral…”
Get full text

Th1 and Th2 epitopes of polymorphic gene 1 of by Ngoepe, Tlou A., Pretorius, Alri, Steyn, Helena C., Van Kleef, Mirinda

“…Cowdria polymorphic gene 1 (cpg1, Erum2510, ERUM_RS01380) has been shown to induce 30% and 100% protection in sheep immunised by deoxyribonucleic acid (DNA)…”
Get full text

Transcriptome analysis of Ehrlichia ruminantium in the ruminant host at the tick bite site and in the tick vector salivary glands by Tjale, Mabotse A., Liebenberg, Junita, Steyn, Helena, Van Kleef, Mirinda, Pretorius, Alri

“…Heartwater is a non-contagious tick-borne disease of domestic and wild ruminants. Data regarding the complex processes involved during pathogen-vector–host…”
Get full text

Virus-specific CD8+ T-cells detected in PBMC from horses vaccinated against African horse sickness virus by Pretorius, Alri, Van Kleef, Mirinda, Van Wyngaardt, Wouter, Heath, Jeanette

“…African horsesickness (AHS) is an infectious but noncontagious viral disease affecting all species of Equidae. The recall immune response of AHSV naïve horses…”
Get full text

The Genome of the Heartwater Agent Ehrlichia ruminantium Contains Multiple Tandem Repeats of Actively Variable Copy Number by Collins, Nicola E., Liebenberg, Junita, de Villiers, Etienne P., Brayton, Kelly A., Louw, Elmarié, Pretorius, Alri, Faber, F. Erika, van Heerden, Henriette, Josemans, Antoinette, van Kleef, Mirinda, Steyn, Helena C., van Strijp, M. Fransie, Zweygarth, Erich, Jongejan, Frans, Maillard, Jean Charles, Berthier, David, Botha, Marli, Joubert, Fourie, Corton, Craig H., Thomson, Nicholas R., Allsopp, Maria T., Allsopp, Basil A., Beaty, Barry J.

“…Heartwater, a tick-borne disease of domestic and wild ruminants, is caused by the intracellular rickettsia Ehrlichia ruminantium (previously known as Cowdria…”
Get full text

Preparation and in vitro characterisation of Ehrlichia ruminantium plasmid DNA and proteins encapsulated into and DNA adsorbed onto biodegradable microparticles by Tshikhudo, Ndavheleseni, Pretorius, Alri, Putterill, John, van Kleef, Mirinda

“…Four E. ruminantium 1H12 open reading frames and their proteins known to protect sheep against heartwater needle challenge were encapsulated into, or adsorbed…”
Get full text

An attenuated Ehrlichia ruminantium (Welgevonden stock) vaccine protects small ruminants against virulent heartwater challenge by Zweygarth, Erich, Josemans, Antoinette I., Van Strijp, M. Fransie, Lopez-Rebollar, Laura, Van Kleef, Mirinda, Allsopp, Basil A.

“…Heartwater is a tick-borne disease of ruminants caused by the intracellular rickettsia Ehrlichia ruminantium. The only commercially available immunization…”
Get full text

An attenuatedEhrlichia ruminantium(Welgevonden stock) vaccine protects small ruminants against virulent heartwater challenge by Zweygarth, Erich, Josemans, Antoinette I, van Strijp, M Fransie, Lopez-Rebollar, Laura, van Kleef, Mirinda, Allsopp, Basil A

“…Heartwater is a tick-borne disease of ruminants caused by the intracellular rickettsiaEhrlichia ruminantium. The only commercially available immunization…”
Get full text

Isolement et caractérisation de protéines antigéniques de Cowdria ruminantium by Van Kleef, Mirinda, Neitz, A.W.H., De Waal, D.T.

“…Deux protéines conservées antigéniquement, une immunodominante de 31 kilodalton et une mineure de 27 kDa, ont été caractérisées. Les protéines de 31 kDa et de…”
Get full text

Development of Improved Vaccines for Heartwater by COLLINS, NICOLA E., PRETORIUS, ALRI, VAN KLEEF, MIRINDA, BRAYTON, KELLY A., ZWEYGARTH, ERICH, ALLSOPP, BASIL A.

“…: Heartwater is a tick‐borne disease of ruminants which causes major economic losses for domestic livestock owners throughout sub‐Saharan Africa and the…”
Get full text

Clonage et caractérisation partielle du gène codant pour la protéine Cr32 de Cowdria ruminantium by Van Vliet, A.H.M., Jongejan, Frans, Van Kleef, Mirinda, Van Der Zeijst, B.A.M.

“…Les Cowdria ont été purifiées par centrifugation en gradient de densité. L'ADN a été utilisé pour la construction de banques génomiques d'expression. La…”
Get full text

Identification of Cowdria ruminantiumAntigens That Stimulate Proliferation of Lymphocytes from Cattle Immunized by Infection and Treatment or with Inactivated Organisms by Mirinda Van Kleef, Nico J. Gunter, Henriette Macmillan, Basil A. Allsopp, Varda Shkap, Wendy C. Brown

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Identification of Cowdria ruminantium antigens that stimulate proliferation of lymphocytes from cattle immunized by infection and treatment or with inactivated organisms by VAN KLEEF, M, GUNTER, N. J, MACMILLAN, H, ALLSOPP, B. A, SHKAP, V, BROWN, W. C

“…Cowdria ruminantium is an obligate intracellular pathogen that causes heartwater in ruminants. Several findings suggest that T cells play an important role in…”
Get full text