Search Results - "Van Houwelingen, Hans C."

Prediction meets causal inference: the role of treatment in clinical prediction models by van Geloven, Nan, Swanson, Sonja A., Ramspek, Chava L., Luijken, Kim, van Diepen, Merel, Morris, Tim P., Groenwold, Rolf H. H., van Houwelingen, Hans C., Putter, Hein, le Cessie, Saskia

“…In this paper we study approaches for dealing with treatment when developing a clinical prediction model. Analogous to the estimand framework recently proposed…”
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The binomial distribution of meta-analysis was preferred to model within-study variability by Hamza, Taye H, van Houwelingen, Hans C, Stijnen, Theo

“…Abstract Objective When studies report proportions such as sensitivity or specificity, it is customary to meta-analyze them using the DerSimonian and Laird…”
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MAGE-A3 immunotherapeutic as adjuvant therapy for patients with resected, MAGE-A3-positive, stage III melanoma (DERMA): a double-blind, randomised, placebo-controlled, phase 3 trial by Dreno, Brigitte, Thompson, John F, Smithers, Bernard Mark, Santinami, Mario, Jouary, Thomas, Gutzmer, Ralf, Levchenko, Evgeny, Rutkowski, Piotr, Grob, Jean-Jacques, Korovin, Sergii, Drucis, Kamil, Grange, Florent, Machet, Laurent, Hersey, Peter, Krajsova, Ivana, Testori, Alessandro, Conry, Robert, Guillot, Bernard, Kruit, Wim H J, Demidov, Lev, Thompson, John A, Bondarenko, Igor, Jaroszek, Jaroslaw, Puig, Susana, Cinat, Gabriela, Hauschild, Axel, Goeman, Jelle J, van Houwelingen, Hans C, Ulloa-Montoya, Fernando, Callegaro, Andrea, Dizier, Benjamin, Spiessens, Bart, Debois, Muriel, Brichard, Vincent G, Louahed, Jamila, Therasse, Patrick, Debruyne, Channa, Kirkwood, John M

“…Despite newly approved treatments, metastatic melanoma remains a life-threatening condition. We aimed to evaluate the efficacy of the MAGE-A3 immunotherapeutic…”
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Dynamic Prediction by Landmarking in Event History Analysis by VAN HOUWELINGEN, HANS C.

“…This article advocates the landmarking approach that dynamically adjusts predictive models for survival data during the follow up. This updating is achieved by…”
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Advanced methods in meta-analysis: multivariate approach and meta-regression by van Houwelingen, Hans C., Arends, Lidia R., Stijnen, Theo

“…This tutorial on advanced statistical methods for meta‐analysis can be seen as a sequel to the recent Tutorial in Biostatistics on meta‐analysis by Normand,…”
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Multivariate random effects meta-analysis of diagnostic tests with multiple thresholds by Hamza, Taye H, Arends, Lidia R, van Houwelingen, Hans C, Stijnen, Theo

“…Bivariate random effects meta-analysis of diagnostic tests is becoming a well established approach when studies present one two-by-two table or one pair of…”
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Genetic Susceptibility to Respiratory Syncytial Virus Bronchiolitis Is Predominantly Associated with Innate Immune Genes by Janssen, Riny, Bont, Louis, Siezen, Christine L. E., Hodemaekers, Hennie M., Ermers, Marieke J., Doornbos, Gerda, Slot, Ruben van 't, Wijmenga, Ciska, Goeman, Jelle J., Kimpen, Jan L. L., van Houwelingen, Hans C., Kimman, Tjeerd G., Hoebee, Barbara

“…Background. Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infection in infants. Only a proportion of children infected…”
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Reduced-rank proportional hazards regression and simulation-based prediction for multi-state models by Fiocco, Marta, Putter, Hein, van Houwelingen, Hans C.

“…In this paper we address two issues arising in multi‐state models with covariates. The first issue deals with how to obtain parsimony in the modeling of the…”
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Validation and updating of predictive logistic regression models: a study on sample size and shrinkage by Steyerberg, Ewout W., Borsboom, Gerard J. J. M., van Houwelingen, Hans C., Eijkemans, Marinus J. C., Habbema, J. Dik F.

“…A logistic regression model may be used to provide predictions of outcome for individual patients at another centre than where the model was developed. When…”
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Cross-validated Cox regression on microarray gene expression data by van Houwelingen, Hans C., Bruinsma, Tako, Hart, Augustinus A. M., van't Veer, Laura J., Wessels, Lodewyk F. A.

“…This paper describes how penalized Cox regression, in combination with cross‐validated partial likelihood can be employed to obtain reliable survival…”
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Dynamic predicting by landmarking as an alternative for multi-state modeling: an application to acute lymphoid leukemia data by van Houwelingen, Hans C., Putter, Hein

“…This paper considers the problem of obtaining a dynamic prediction for 5-year failure free survival after bone marrow transplantation in ALL patients using…”
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Travel-related venous thrombosis: results from a large population-based case control study (MEGA study) by Cannegieter, Suzanne C, Doggen, Carine J M, van Houwelingen, Hans C, Rosendaal, Frits R

“…Recent studies have indicated an increased risk of venous thrombosis after air travel. Nevertheless, questions on the magnitude of risk, the underlying…”
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Testing against a high-dimensional alternative in the generalized linear model: asymptotic type I error control by GOEMAN, JELLE J., VAN HOUWELINGEN, HANS C., FINOS, LIVIO

“…Testing a low-dimensional null hypothesis against a high-dimensional alternative in a generalized linear model may lead to a test statistic that is a quadratic…”
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Validation, calibration, revision and combination of prognostic survival models by van Houwelingen, Hans C.

“…The problem of assessing the validity and value of prognostic survival models presented in the literature for a particular population for which some data has…”
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Renal histology in ANCA-associated vasculitis: Differences between diagnostic and serologic subgroups by Hauer, Herbert A., Bajema, Ingeborg M., Van Houwelingen, Hans C., Ferrario, Franco, Noël, Laure-Hélène, Waldherr, Rüdiger, Jayne, David R.W., Rasmussen, Niels, Bruijn, Jan A., Hagen, E. Christiaan

“…Renal histology in ANCA-associated vasculitis: Differences between diagnostic and serologic subgroups. Differences in renal histopathology between microscopic…”
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Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico-histopathological analysis of 96 patients by Hauer, Herbert A., Bajema, Ingeborg M., Van Houwelingen, Hans C., Ferrario, Franco, Noël, Laure-Hélène, Waldherr, Rüdiger, Jayne, David R.W., Rasmussen, Niels, Bruijn, Jan A., Hagen, E. Christiaan

“…Determinants of outcome in ANCA-associated glomerulonephritis: A prospective clinico-histopathological analysis of 96 patients. The predictive value of…”
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Landmarking 2.0: Bridging the gap between joint models and landmarking by Putter, Hein, Houwelingen, Hans C.

“…The problem of dynamic prediction with time‐dependent covariates, given by biomarkers, repeatedly measured over time, has received much attention over the last…”
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A simple method for co-segregation analysis to evaluate the pathogenicity of unclassified variants; BRCA1 and BRCA2 as an example by Mohammadi, Leila, Vreeswijk, Maaike P, Oldenburg, Rogier, van den Ouweland, Ans, Oosterwijk, Jan C, van der Hout, Annemarie H, Hoogerbrugge, Nicoline, Ligtenberg, Marjolijn, Ausems, Margreet G, van der Luijt, Rob B, Dommering, Charlotte J, Gille, Johan J, Verhoef, Senno, Hogervorst, Frans B, van Os, Theo A, Gómez García, Encarna, Blok, Marinus J, Wijnen, Juul T, Helmer, Quinta, Devilee, Peter, van Asperen, Christi J, van Houwelingen, Hans C

“…Assessment of the clinical significance of unclassified variants (UVs) identified in BRCA1 and BRCA2 is very important for genetic counselling. The analysis of…”
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On the relation between the cause‐specific hazard and the subdistribution rate for competing risks data: The Fine–Gray model revisited by Putter, Hein, Schumacher, Martin, van Houwelingen, Hans C.

“…The Fine–Gray proportional subdistribution hazards model has been puzzling many people since its introduction. The main reason for the uneasy feeling is that…”
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Results of the Dutch National Study of the Palliative Effect of Irradiation Using Two Different Treatment Schemes for Non–Small-Cell Lung Cancer by KRAMER, Gijsbert W. P. M, WANDERS, Stofferinus L, NOORDIJK, Ed M, VONK, Ernest J. A, VAN HOUWELINGEN, Hans C, VAN DEN HOUT, Wilbert B, GESKUS, Ronald B, SCHOLTEN, Mirjam, LEER, Jan-Willem H

“…A national multicenter randomized study compared the efficacy of 2 x 8 Gy versus our standard 10 x 3 Gy in patients with inoperable stage IIIA/B (with an…”
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