Search Results - "Van Hoek, Alfred"

High resolution helium ion scanning microscopy of the rat kidney by Rice, William L, Van Hoek, Alfred N, Păunescu, Teodor G, Huynh, Chuong, Goetze, Bernhard, Singh, Bipin, Scipioni, Larry, Stern, Lewis A, Brown, Dennis

“…Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So…”
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Collecting duct-specific knockout of renin attenuates angiotensin II-induced hypertension by Ramkumar, Nirupama, Stuart, Deborah, Rees, Sara, Hoek, Alfred Van, Sigmund, Curt D, Kohan, Donald E

“…The physiological and pathophysiological significance of collecting duct (CD)-derived renin, particularly as it relates to blood pressure (BP) regulation, is…”
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Nephron-specific deletion of the prorenin receptor causes a urine concentration defect by Ramkumar, Nirupama, Stuart, Deborah, Calquin, Matias, Quadri, Syed, Wang, Shuping, Van Hoek, Alfred N, Siragy, Helmy M, Ichihara, Atsuhiro, Kohan, Donald E

“…The prorenin receptor (PRR), a recently discovered component of the renin-angiotensin system, is expressed in the nephron in general and the collecting duct in…”
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Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice by Paunescu, Teodor G, Russo, Leileata M, Da Silva, Nicolas, Kovacikova, Jana, Mohebbi, Nilufar, Van Hoek, Alfred N, McKee, Mary, Wagner, Carsten A, Breton, Sylvie, Brown, Dennis

“…Mice deficient in the ATP6V1B1 ("B1") subunit of the vacuolar proton-pumping ATPase (V-ATPase) maintain body acid-base homeostasis under normal conditions, but…”
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Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking by Crane, Jonathan M, Van Hoek, Alfred N, Skach, William R, Verkman, A S

“…Freeze-fracture electron microscopy (FFEM) indicates that aquaporin-4 (AQP4) water channels can assemble in cell plasma membranes in orthogonal arrays of…”
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Rapid Identification of Novel Inhibitors of the Human Aquaporin-1 Water Channel by Patil, Rajkumar V., Xu, Shouxi, van Hoek, Alfred N., Rusinko, Andrew, Feng, Zixia, May, Jesse, Hellberg, Mark, Sharif, Najam A., Wax, Martin B., Irigoyen, Macarena, Carr, Grant, Brittain, Tom, Brown, Peter, Colbert, Damon, Kumari, Sindhu, Varadaraj, Kulandaiappan, Mitra, Alok K.

“…Aquaporins (AQPs) are a family of membrane proteins that function as channels facilitating water transport in response to osmotic gradients. These play…”
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Paracellular Cl- Permeability Is Regulated by WNK4 Kinase: Insight into Normal Physiology and Hypertension by Kahle, Kristopher T., MacGregor, Gordon G., Wilson, Frederick H., Van Hoek, Alfred N., Brown, Dennis, Ardito, Thomas, Kashgarian, Michael, Giebisch, Gerhard, Hebert, Steven C., Boulpaep, Emile L., Lifton, Richard P.

“…Paracellular ion flux across epithelia occurs through selective and regulated pores in tight junctions; this process is poorly understood. Mutations in the…”
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Membrane organization and function of M1 and M23 isoforms of aquaporin-4 in epithelial cells by Silberstein, Claudia, Bouley, Richard, Huang, Yan, Fang, Pingke, Pastor-Soler, Nuria, Brown, Dennis, Van Hoek, Alfred N

“…Aquaporin-4 (AQP4) water channels exist as heterotetramers of M1 and M23 splice variants and appear to be present in orthogonal arrays of intramembraneous…”
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Postnatal Expression of Aquaporins in Epithelial Cells of the Rat Epididymis by DA SILVA, Nicolas, SILBERSTEIN, Claudia, BEAULIEU, Valérie, PIETREMENT, Christine, VAN HOEL, Alfred N, BROWN, Dennis, BRETON, Sylvie

“…The mammalian aquaporins (AQPs) are a family of 13 transmembrane channel proteins that are involved in the transport of water in numerous organs. In the male…”
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Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice by Chou, C L, Knepper, M A, Hoek, A N, Brown, D, Yang, B, Ma, T, Verkman, A S

“…It has been controversial whether high water permeability in the thin descending limb of Henle (TDLH) is required for formation of a concentrated urine by the…”
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Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure by Kittikulsuth, Wararat, Stuart, Deborah, Van Hoek, Alfred N, Stockand, James D, Bugaj, Vladislav, Mironova, Elena, Blount, Mitsi A, Kohan, Donald E

“…cAMP is a key mediator of connecting tubule and collecting duct (CD) Na(+) and water reabsorption. Studies performed in vitro have suggested that CD adenylyl…”
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Aquaporin-4 is expressed in basolateral membranes of proximal tubule S3 segments in mouse kidney by van Hoek, A N, Ma, T, Yang, B, Verkman, A S, Brown, D

“…Because of the availability of knockout mouse models to examine renal transport mechanisms, it has become increasingly important to describe the cellular…”
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Post‐Golgi Supramolecular Assembly of Aquaporin‐4 in Orthogonal Arrays by Rossi, Andrea, Baumgart, Florian, van Hoek, Alfred N., Verkman, A. S.

“…The supramolecular assembly of aquaporin‐4 (AQP4) in orthogonal arrays of particles (OAPs) involves N‐terminus interactions of the M23‐AQP4 isoform. We found…”
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Role of NHERF1, Cystic Fibrosis Transmembrane Conductance Regulator, and cAMP in the Regulation of Aquaporin 9 by Pietrement, Christine, Da Silva, Nicolas, Silberstein, Claudia, James, Marianne, Marsolais, Mireille, Van Hoek, Alfred, Brown, Dennis, Pastor-Soler, Nuria, Ameen, Nadia, Laprade, Raynald, Ramesh, Vijaya, Breton, Sylvie

“…Water and solute transport across the plasma membrane of cells is a crucial biological function that is mediated mainly by aquaporins and aquaglyceroporins…”
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Identification of adenylyl cyclase isoforms mediating parathyroid hormone- and calcitonin-stimulated cyclic AMP accumulation in distal tubule cells by Kittikulsuth, Wararat, Friedman, Peter A, van Hoek, Alfred, Gao, Yang, Kohan, Donald E

“…The distal convoluted tubule (DCT) is an important nephron site for parathyroid hormone (PTH) and calcitonin regulation of urinary divalent cation excretion…”
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Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones by Pastor-Soler, Núria M, Fisher, Jane S, Sharpe, Richard, Hill, Eric, Van Hoek, Alfred, Brown, Dennis, Breton, Sylvie

“…Fluid and solute transport across the epithelium of the male excurrent duct is important for sperm maturation and storage. Aquaporin 9 (AQP9), which allows…”
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Lack of an effect of nephron‐specific deletion of adenylyl cyclase 3 on renal sodium and water excretion or arterial pressure by Kittikulsuth, Wararat, Stuart, Deborah, Van Hoek, Alfred N., Kohan, Donald E.

“…Adenylyl cyclase (AC)‐stimulated cAMP plays a key role in modulating transport and channel activity along the nephron. However, the role of individual adenylyl…”
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Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays by Van Hoek, Alfred N, Bouley, Richard, Lu, Yingxian, Silberstein, Claudia, Brown, Dennis, Wax, Martin B, Patil, Rajkumar V

“…Aquaporin-4 (AQP4) is a basolateral water channel in collecting duct principal cells and assembles into orthogonal array particles (OAPs), the size of which…”
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A point mutation at cysteine 189 blocks the water permeability of rat kidney water channel CHIP28k by Zhang, Rubin, van Hoek, Alfred N, Biwersi, Joachim, Verkman, A. S

“…CHIP28k is an important water-transporting protein in the kidney proximal tubule and the thin descending limb of Henle [Zhang, Skach, Hasegawa, Van Hoek, &…”
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Carbon Dioxide Permeability of Aquaporin-1 Measured in Erythrocytes and Lung of Aquaporin-1 Null Mice and in Reconstituted Proteoliposomes by Yang, Baoxue, Fukuda, Norimasa, van Hoek, Alfred, Matthay, Michael A., Ma, Tonghui, Verkman, A.S.

“…Measurements of CO2permeability in oocytes and liposomes containing water channel aquaporin-1 (AQP1) have suggested that AQP1 is able to transport both water…”
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