Search Results - "Van Hoecke, Michaël"
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Glucose and NADPH oxidase drive neuronal superoxide formation in stroke
Published in Annals of neurology (01-12-2008)“…Objective Hyperglycemia has been recognized for decades to be an exacerbating factor in ischemic stroke, but the mechanism of this effect remains unresolved…”
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Hypoxia induces caspase-9 and caspase-3 activation without neuronal death in gerbil brains
Published in The European journal of neuroscience (01-08-2004)“…To investigate the in vivo apoptotic machinery in oxygen deprived brain, we examined the expression of caspase‐9 and caspase‐3 in the hippocampus of Mongolian…”
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Pyruvate protects against experimental stroke via an anti-inflammatory mechanism
Published in Neurobiology of disease (01-10-2009)“…Abstract Pyruvate, a key intermediate in glucose metabolism, was explored as a potential treatment in models of experimental stroke and inflammation. Pyruvate…”
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Evidence of HIF-1 functional binding activity to caspase-3 promoter after photothrombotic cerebral ischemia
Published in Molecular and cellular neuroscience (2007)“…Hypoxia-inducible factor 1 α (HIF-1α) is a transcription factor that was suggested in vitro to promote cell death by modulation of proapoptotic genes. In this…”
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Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2′-dipyridyl
Published in The European journal of neuroscience (01-09-2005)“…Two different forms of cell death have been distinguished morphologically following cerebral ischaemia: necrotic and apoptotic cell death. The aim of this…”
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