Search Results - "Van Helden, Dusty"

Precision Targeted Ablation of Fine Neurovascular Structures In Vivo Using Dual-mode Ultrasound Arrays by Aravalli, Rajagopal N., Helden, Dusty Van, Liu, Dalong, O’Brien, Parker, Aldiabat, Hasan, Tăbăran, Alexandru-Flaviu, O’Sullivan, M. Gerard, Clark, H. Brent, Osborn, John W., Ebbini, Emad S.

“…Carotid bodies (CBs) are chemoreceptors that monitor and register changes in the blood, including the levels of oxygen, carbon dioxide, and pH, and regulate…”
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Renal Inflammation in DOCA-Salt Hypertension: Role of Renal Nerves and Arterial Pressure by Banek, Christopher T, Gauthier, Madeline M, Van Helden, Dusty A, Fink, Gregory D, Osborn, John W

“…Recent reports indicate that, in addition to treating hypertension, renal denervation (RDN) also mitigates renal inflammation. However, because RDN decreases…”
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Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes by Egbert, Jeremy R, Shuhaibar, Leia C, Edmund, Aaron B, Van Helden, Dusty A, Robinson, Jerid W, Uliasz, Tracy F, Baena, Valentina, Geerts, Andreas, Wunder, Frank, Potter, Lincoln R, Jaffe, Laurinda A

“…In mammals, the meiotic cell cycle of oocytes starts during embryogenesis and then pauses. Much later, in preparation for fertilization, oocytes within…”
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Chronic Low-Level Vagus Nerve Stimulation Improves Long-Term Survival in Salt-Sensitive Hypertensive Rats by Annoni, Elizabeth M, Van Helden, Dusty, Guo, Yugene, Levac, Brett, Libbus, Imad, KenKnight, Bruce H, Osborn, John W, Tolkacheva, Elena G

“…Chronic hypertension (HTN) affects more than 1 billion people worldwide, and is associated with an increased risk of cardiovascular disease. Despite decades of…”
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IL-1R mediated renal sensory nerve activity drives hypertension in the DOCA-Salt mouse by Baumann, Daniel, Van Helden, Dusty, Evans, Louise, Osborn, John

“…Abstract only Clinical trials of renal denervation (RDN) have shown unanticipated changes in non-renal sympathetic activity. It has been hypothesized that this…”
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Micromagnetic Neural Stimulation and Spintronic Neural Sensing by Saha, Renata, Tonini, Denis, Hopper, Matthew S., Goyal, Abhinav, Yuen, Jason, Oh, Yoonbae, Sanger, Zachary, Faramarzi, Sadegh, Shiao, Maple, Van Helden, Dusty, Bloom, Robert P., Benally, Onri J., Wu, Kai, Keirstead, Susan A., Netoff, Theoden I., Low, Walter C., Osborn, John, Bennet, Kevin E., Lee, Kendall H., Shin, Hojin, Wang, Jian-Ping

“…We report our team's recent magnetic biomedical brain-related research work: 1) micromagnetic neural stimulation (\boldsymbol{\mu} \mathbf{MS}) ; 2)…”
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SPARC: Renal Denervation Attenuates DOCA‐salt Hypertension in the Mouse by Baumann, Daniel C., Van Helden, Dusty, Evans, Louise, Osborn, John

“…Abstract only Hypertension affects approximately one third of the adult population in the United States. Catheter based renal denervation (RDN) has emerged as…”
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Abstract 032: Afferent Renal Denervation And IL-1 Receptor Blockade Attenuate The Pathogenesis Of Hypertension In DOCA-salt Mice Similarly: Evidence For A Common Mechanism? by Baumann, Daniel C, Van Helden, Dusty A, Evans, Louise C, Osborn, John W

“…Abstract only Emerging evidence suggests an interaction between renal inflammation and afferent renal nerves in some preclinical models of hypertension. In…”
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OVLT lesion decreases arterial pressure, water intake, vasopressin, and renal inflammation in 2-kidney, 1-clip rats by Lauar, Mariana, Pestana-Oliveira, Nayara, Van Helden, Dusty, Collister, John, Evans, Louise, Osborn, John

“…Abstract only Hypertension (HTN) is a multifactorial disease affecting one-third of adults in western society. It is well established that renal artery…”
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Resting Afferent Renal Nerve Discharge and Renal Inflammation: Elucidating the Role of Afferent and Efferent Renal Nerves in Deoxycorticosterone Acetate Salt Hypertension by Banek, Christopher T, Knuepfer, Mark M, Foss, Jason D, Fiege, Jessica K, Asirvatham-Jeyaraj, Ninitha, Van Helden, Dusty, Shimizu, Yoji, Osborn, John W

“…Renal sympathetic denervation (RDNx) has emerged as a novel therapy for hypertension; however, the therapeutic mechanisms remain unclear. Efferent renal…”
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IL-1R Mediated Activation of Renal Sensory Nerves in DOCA-Salt Hypertension by Baumann, Daniel, Van Helden, Dusty, Evans, Louise C, Vulchanova, Lucy, Dayton, Alex, Osborn, John W

“…Clinical trials of renal denervation for the treatment of hypertension have shown a variety of off-target improvements in conditions associated with…”
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Afferent renal denervation attenuates DOCA‐salt hypertension in the mouse: Potential role of an IL‐1β afferent renal nerve interaction by Baumann, Daniel C., Van Helden, Dusty, Evans, Louise, Osborn, John W.

“…Catheter based renal denervation (RDN) has emerged as a novel treatment for hypertension in patients. However, the mechanisms by which RDN lowers arterial…”
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Use of the Peregrine Catheter Infusion System to develop novel targeted renal nerve ablation therapies in hypertensive sheep by de la Cruz-Lynch, Arthur, Van Helden, Dusty, Dayton, Alex, Evans, Louise, Ruiz Lauar, Mariana, Osborn, John

“…Abstract only Background and Objective: Clinical trials have shown that catheter-based total (efferent and afferent) renal denervation (TRDN) can effectively…”
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SPARC ‐ The Functional Anatomy of Murine Myelinated Renal Afferents by Schramm, Lawrence P., Tyshynsky, Roman S., Van Helden, Dusty A., Osborn, John W.

“…Abstract only Perhaps because they are a small minority of the total population of renal afferents, myelinated renal afferents (MRA ) have been the least…”
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Abstract 075: The Kidney-OVLT Neuroaxis Mediates Neurogenic Hypertension And Polydipsia In 2-Kidney, 1-Clip Rats by Ruiz Lauar, Mariana, Pestana-Oliveira, Nayara, Vulchanova, Lucy, Van Helden, Dusty, Collister, John P, Banek, Christopher T, Evans, Louise C, Menani, José V, Osborn, John W

“…Abstract only Renal afferent nerves mediate activation of the sympathetic nervous system and hypertension in rats with unilateral renal artery stenosis…”
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OVLT Lesion attenuates hypertension and polydipsia in 2‐kidney, 1‐clip hypertensive Rats by Ruiz Lauar, Mariana, Pestana‐Oliveira, Nayara, Van Helden, Dusty, Collister, John P., Osborn, John W.

“…Hypertension (HTN) is a multifaceted condition that affects one‐third of the population of western countries. It is well established that renal ischemia…”
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TRPV1+ Sensory Fibers in the Mouse Renal Cortex ‐ Juxtaglomerular Anatomy and Optogenetic Stimulation by Tyshynsky, Roman, Van Helden, Dusty, Baumann, Daniel C., Sensarma, Sulagna, Kram, Rachel, Vulchanova, Lucy, Osborn, John W.

“…Hypertension is the leading contributor to cardiovascular‐related deaths worldwide. To overcome obstacles presented by traditional drug‐based therapies for…”
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The effect of perimenopause on the pathogenesis of hypertension in female DOCA-salt rats by Pestana-Oliveira, Nayara, Ruiz Lauar, Mariana, Van Helden, Dusty, Almutlaq, Rawan, de la Cruz-Ly, Arthur, Ross, Jaryd, Keller-Ross, Manda, Osborn, John

“…Abstract only The risk of hypertension (HTN) in young females is lower than in young males, but this risk increases in postmenopausal females and surpasses…”
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Abstract 019: Perimenopause Exacerbates Hypertension In Doca-salt Rats by Pestana-Oliveira, Nayara, Ruiz Lauar, Mariana, Almutlaq, Rawan, de la Cruz-Lynch, Arthur T, Ross, Jaryd, Van Helden, Dusty A, Dayton, Alex, Evans, Louise C, Keller-Ross, Manda L, Osborn, John W

“…Abstract only Blood pressure (BP) is lower in premenopausal women than in age-matched men, but after menopause BP rates and the incidence of hypertension (HTN)…”
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Renal and hypothalamic inflammation in renovascular hypertension: role of afferent renal nerves by Lauar, Mariana R, Evans, Louise C, Van Helden, Dusty, Fink, Gregory D, Banek, Christopher T, Menani, José V, Osborn, John W

“…Renal denervation (RDN) is a potential therapy for drug-resistant hypertension. However, whether its effects are mediated by ablation of efferent or afferent…”
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