Search Results - "Van Guyse, Joachim F R"

Bioresponsive Polymers for Nanomedicine-Expectations and Reality by Quader, Sabina, Van Guyse, Joachim F R

“…Bioresponsive polymers in nanomedicine have been widely perceived to selectively activate the therapeutic function of nanomedicine at diseased or pathological…”
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Enzymatically Transformable Polymersome‐Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer by Li, Junjie, Ge, Zhishen, Toh, Kazuko, Liu, Xueying, Dirisala, Anjaneyulu, Ke, Wendong, Wen, Panyue, Zhou, Hang, Wang, Zheng, Xiao, Shiyan, Van Guyse, Joachim F. R., Tockary, Theofilus A., Xie, Jinbing, Gonzalez‐Carter, Daniel, Kinoh, Hiroaki, Uchida, Satoshi, Anraku, Yasutaka, Kataoka, Kazunori

“…Prevention of metastatic and local‐regional recurrence of cancer after surgery remains difficult. Targeting postsurgical premetastatic niche and microresiduals…”
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Stoichiometric Control over Partial Transesterification of Polyacrylate Homopolymers as Platform for Functional Copolyacrylates by Van Guyse, Joachim F. R., Bernhard, Yann, Hoogenboom, Richard

“…Only recently, post‐polymerization modification reactions of unactivated polyacrylates have been emerging as an attractive alternative to utilizing reactive…”
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Non‐activated Esters as Reactive Handles in Direct Post‐Polymerization Modification by Van Guyse, Joachim F. R., Bernhard, Yann, Podevyn, Annelore, Hoogenboom, Richard

“…Non‐activated esters are prominently featured functional groups in polymer science, as ester functional monomers display great structural diversity and…”
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Effective mRNA Protection by Poly(l‐ornithine) Synergizes with Endosomal Escape Functionality of a Charge‐Conversion Polymer toward Maximizing mRNA Introduction Efficiency by Dirisala, Anjaneyulu, Uchida, Satoshi, Li, Junjie, Van Guyse, Joachim F. R., Hayashi, Kotaro, Vummaleti, Sai V. C., Kaur, Sarandeep, Mochida, Yuki, Fukushima, Shigeto, Kataoka, Kazunori

“…For efficient delivery of messenger (m)RNA, delivery carriers need two major functions: protecting mRNA from nucleases and translocating mRNA from…”
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Accelerated Post‐Polymerization Amidation of Polymers with Side‐Chain Ester Groups by Intramolecular Activation by Van Guyse, Joachim F. R., Leiske, Meike N., Verjans, Jente, Bernhard, Yann, Hoogenboom, Richard

“…The catalytic conversion of esters to amides represents new opportunities in the synthetic diversification and upcycling of polymers, as esters are commonly…”
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Facile Generation of Heterotelechelic Poly(2‐Oxazoline)s Towards Accelerated Exploration of Poly(2‐Oxazoline)‐Based Nanomedicine by Van Guyse, Joachim F. R., Abbasi, Saed, Toh, Kazuko, Nagorna, Zlata, Li, Junjie, Dirisala, Anjaneyulu, Quader, Sabina, Uchida, Satoshi, Kataoka, Kazunori

“…Controlling the end‐groups of biocompatible polymers is crucial for enabling polymer‐based therapeutics and nanomedicine. Typically, end‐group diversification…”
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Full and Partial Amidation of Poly(methyl acrylate) as Basis for Functional Polyacrylamide (Co)Polymers by Van Guyse, Joachim F. R, Verjans, Jente, Vandewalle, Stef, De Bruycker, Kevin, Du Prez, Filip E, Hoogenboom, Richard

“…The direct modification of poly­(methyl acrylate) (PMA) to obtain functional poly­(acrylate ester)­s or poly­(N-alkyl acrylamide)­s is generally considered to…”
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Poly(2-ethyl-2-oxazoline) Conjugates with Salicylic Acid via Degradable Modular Ester Linkages by Bernhard, Yann, Sedlacek, Ondrej, Van Guyse, Joachim F. R, Bender, Johan, Zhong, Zifu, De Geest, Bruno G, Hoogenboom, Richard

“…Conjugation of drugs to polymers is a widely used approach to gain control over the release of therapeutics. In this contribution, salicylic acid, a…”
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Water-Stable Plasma-Polymerized N,N‑Dimethylacrylamide Coatings to Control Cellular Adhesion by Egghe, Tim, Cools, Pieter, Van Guyse, Joachim F. R, Asadian, Mahtab, Khalenkow, Dmitry, Nikiforov, Anton, Declercq, Heidi, Skirtach, Andre G, Morent, Rino, Hoogenboom, Richard, De Geyter, Nathalie

“…The plasma polymerization of amide-based precursors is a nearly unexplored research area, which is in contrast with the abundance of reports focusing on…”
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Metal Ion Selective Self‐Assembly of a Ligand Functionalized Polymer into [1+1] Macrocyclic and Supramolecular Polymer Structures via Metal–Ligand Coordination by Xu, Xiaowen, Guyse, Joachim F. R., Jerca, Valentin Victor, Hoogenboom, Richard

“…The design and synthesis of polymer‐based metallomacrocycles relying on metal–ligand interactions remain a challenge in the polymer field. Instead of utilizing…”
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Poly(2-allylamidopropyl-2-oxazoline)-Based Hydrogels: From Accelerated Gelation Kinetics to In Vivo Compatibility in a Murine Subdermal Implant Model by Dargaville, Tim R, Harkin, Damien G, Park, Jong-Ryul, Cavalcanti, Amanda, Bolle, Eleonore C. L, Savi, Flavia Medeiros, Farrugia, Brooke L, Monnery, Bryn D, Bernhard, Yann, Van Guyse, Joachim F. R, Podevyn, Annelore, Hoogenboom, Richard

“…A rapid photo-curing system based on poly­(2-ethyl-2-oxazoline-co-2-allylamidopropyl-2-oxazoline) and its in vivo compatibility are presented. The base polymer…”
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Influence of the Aliphatic Side Chain on the Near Atmospheric Pressure Plasma Polymerization of 2‑Alkyl-2-oxazolines for Biomedical Applications by Van Guyse, Joachim F. R, Cools, Pieter, Egghe, Tim, Asadian, Mahtab, Vergaelen, Maarten, Rigole, Petra, Yan, Wenqing, Benetti, Edmondo M, Jerca, Valentin-Victor, Declercq, Heidi, Coenye, Tom, Morent, Rino, Hoogenboom, Richard, De Geyter, Nathalie

“…Plasma polymerization is gaining popularity as a technique for coating surfaces due to the low cost, ease of operation, and substrate-independent nature…”
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Mechanochemical Preparation of Stable Sub‐100 nm γ‐Cyclodextrin:Buckminsterfullerene (C60) Nanoparticles by Electrostatic or Steric Stabilization by Van Guyse, Joachim F. R., de la Rosa, Victor R., Hoogenboom, Richard

“…Buckminster fullerene (C60)′s main hurdle to enter the field of biomedicine is its low bioavailability, which results from its extremely low water solubility…”
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Adamantane Functionalized Poly(2-oxazoline)s with Broadly Tunable LCST-Behavior by Molecular Recognition by Van Guyse, Joachim F R, Bera, Debaditya, Hoogenboom, Richard

“…Smart or adaptive materials often utilize stimuli-responsive polymers, which undergo a phase transition in response to a given stimulus. So far, various…”
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Immiscibility of Chemically Alike Amorphous Polymers: Phase Separation of Poly(2-ethyl-2-oxazoline) and Poly(2‑n‑propyl-2-oxazoline) by Schoolaert, Ella, Merckx, Ronald, Becelaere, Jana, Everaerts, Melissa, Van Guyse, Joachim F. R, Sedlacek, Ondrej, De Geest, Bruno G, Van den Mooter, Guy, D’hooge, Dagmar R, De Clerck, Karen, Hoogenboom, Richard

“…In biomedicine, polymer blends are frequently applied in wound dressing design or drug delivery. Within these applications, poly­(2-alkyl/aryl-2-oxazoline)­s…”
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Poly(N‐isopropylacrylamide) and Its Copolymers: A Review on Recent Advances in the Areas of Sensing and Biosensing by Das, Anubhab, Babu, Anashwara, Chakraborty, Sourav, Van Guyse, Joachim F. R., Hoogenboom, Richard, Maji, Samarendra

“…Stimuli‐responsive polymers have received increasing attention for various applications due to their ability to adapt physical and chemical properties in…”
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Development of reversibly photo-crosslinkable water-stable poly(2-ethyl-2-oxazoline) nanofibers via functionalization with cinnamoyl moieties by Frateur, Olmo, Becelaere, Jana, Merckx, Ronald, F. R. Van Guyse, Joachim, Purino, Martin, Hoogenboom, Richard, De Clerck, Karen

“…[Display omitted] •Successful modification of poly(2-ethyl-2-oxazoline) with cinnamoyl groups.•Nanofibrous membranes of cinnamoyl modified…”
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Stable amorphous solid dispersion of flubendazole with high loading via electrospinning by Becelaere, Jana, Van Den Broeck, Elias, Schoolaert, Ella, Vanhoorne, Valérie, Van Guyse, Joachim F.R., Vergaelen, Maarten, Borgmans, Sander, Creemers, Karolien, Van Speybroeck, Veronique, Vervaet, Chris, Hoogenboom, Richard, De Clerck, Karen

“…In this work, an important step is taken towards the bioavailability improvement of poorly water-soluble drugs, such as flubendazole (Flu), posing a challenge…”
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Amphiphilic Poly(2-oxazoline)s with Glycine-Containing Hydrophobic Blocks Tailored for Panobinostat- and Imatinib-Loaded Micelles by Göppert, Natalie E., Quader, Sabina, Van Guyse, Joachim F. R., Weber, Christine, Kataoka, Kazunori, Schubert, Ulrich S.

“…Aiming toward the development of tailored carrier materials for the cytostatics panobinostat and imatinib, an amphiphilic block copolymer composed of…”
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