Search Results - "Van Gele, M"

The many faces of interleukin-17 in inflammatory skin diseases by Speeckaert, R., Lambert, J., Grine, L., Van Gele, M., De Schepper, S., van Geel, N.

“…Summary Interleukin (IL)‐17 is an emerging target for inflammatory skin disorders. Given the remarkable success of its therapeutic inhibition in psoriasis, the…”
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Peritumoral indoleamine 2,3-dioxygenase expression in melanoma: an early marker of resistance to immune control? by Chevolet, I., Speeckaert, R., Haspeslagh, M., Neyns, B., Krüse, V., Schreuer, M., Van Gele, M., Van Geel, N., Brochez, L.

“…Summary Background Indoleamine 2,3‐dioxygenase (IDO) is an emerging immunomodulating factor in cancer. IDO expression in tumour‐negative sentinel lymph nodes…”
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Characterization of the in vivo immune network of IDO, tryptophan metabolism, PD-L1, and CTLA-4 in circulating immune cells in melanoma by Chevolet, I, Speeckaert, R, Schreuer, M, Neyns, B, Krysko, O, Bachert, C, Hennart, B, Allorge, D, van Geel, N, Van Gele, M, Brochez, L

“…In melanoma, both the induction of immunosuppression by tumor cells and the inflammatory antitumor response can induce an upregulation of counter-regulatory…”
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microRNAs in psoriasis: leaders or followers? by Lambert, J.L.W., Grine, L., Van Gele, M.

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Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy by Speeckaert, R., van Geel, N., Vermaelen, K. V., Lambert, J., Van Gele, M., Speeckaert, M. M., Brochez, L.

“…Summary Spontaneous regression of benign and malignant melanocytic lesions can be a visible sign of immunosurveillance. In this review, we discuss different…”
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Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression by Denecker, G, Vandamme, N, Akay, Ö, Koludrovic, D, Taminau, J, Lemeire, K, Gheldof, A, De Craene, B, Van Gele, M, Brochez, L, Udupi, G M, Rafferty, M, Balint, B, Gallagher, W M, Ghanem, G, Huylebroeck, D, Haigh, J, van den Oord, J, Larue, L, Davidson, I, Marine, J-C, Berx, G

“…Deregulation of signaling pathways that control differentiation, expansion and migration of neural crest-derived melanoblasts during normal development…”
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Mutation analysis of P73 and TP53 in Merkel cell carcinoma by VAN GELE, M, KAGHAD, M, DE WOLF-PEETERS, C, DE PAEPE, A, CAPUT, D, SPELEMAN, F, LEONARD, J. H, VAN ROY, N, NAEYAERT, J. M, GEERTS, M. L, VAN BELLE, S, COCQUYT, V, BRIDGE, J, SCIOT, R

“…The p73 gene has been mapped to 1p36.33, a region which is frequently deleted in a wide variety of neoplasms including tumours of neuroectodermal origin. The…”
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Identifying targets for topical RNAi therapeutics in psoriasis: assessment of a new in vitro psoriasis model by Bracke, S., Desmet, E., Guerrero-Aspizua, S., Tjabringa, S. G., Schalkwijk, J., Van Gele, M., Carretero, M., Lambert, J.

“…Diseases of the skin are amenable to RNAi-based therapies and targeting key components in the pathophysiology of psoriasis using RNAi may represent a…”
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Cutaneous short-interfering RNA therapy by Geusens, B, Sanders, N, Prow, T, Van Gele, M, Lambert, J

“…Since the 1990s, RNA interference (RNAi) has become a major subject of interest, not only as a tool for biological research, but also, more importantly, as a…”
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Ultradeformable cationic liposomes for delivery of small interfering RNA (siRNA) into human primary melanocytes by Geusens, B., Lambert, J., De Smedt, S.C., Buyens, K., Sanders, N.N., Van Gele, M.

“…The aim of this work was to develop a system that can deliver siRNA into cells present in the human epidermis. More specifically, we wanted to block the…”
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micro RNA s in psoriasis: leaders or followers? by Lambert, J.L.W., Grine, L., Van Gele, M.

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Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes by Van Roy, N, Laureys, G, Van Gele, M, Opdenakker, G, Miura, R, van der Drift, P, Chan, A, Versteeg, R, Speleman, F

“…Deletions and translocations resulting in loss of distal 1p-material are known to occur frequently in advanced neuroblastomas. Fluorescence in situ…”
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439 Identification of biomarkers to predict therapeutic response to biologicals in psoriasis by Grine, L., de Medeiros, A.K., Van Gele, M., Spuls, P., Speeckaert, R., Lambert, J.

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OC-0017: Combined High Dose Radiation and Ipilimumab in Metastatic Melanoma, a Phase I Dose Escalation Trial by De Wolf, K., Kruse, V., Brochez, L., Sundahl, N., Van Gele, M., Speeckaert, R., Ost, P.

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Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis by Van Gele, M, Van Roy, N, Jauch, A, Laureys, G, Benoit, Y, Schelfhout, V, De Potter, C.R, Brock, P, Uyttebroeck, A, Sciot, R, Schuuring, E, Versteeg, R, Speleman, F

“…Deletions of the short arm of chromosome 1, extra copies of chromosome 17q and MYCN amplification are the most frequently encountered genetic changes in…”
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Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas by Van Gele, M., Van Roy, N., Ronan, S. G., Messiaen, L., Vandesompele, J., Geerts, M. L., Naeyaert, J. M., Blennow, E., Bar-Am, I., Das Gupta, T. K., van der Drift, P., Versteeg, R., Leonard, J. H., Speleman, F.

“…Merkel cell carcinoma (MCC) is a rare aggressive neuroendocrine tumor of the skin. Only little information is available on the genetic alterations occurring in…”
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Stromal protein expression in breast cancer is differentially regulated by TGF-&bgr;1 by Van Bockstal, M., Lambein, K., Van Gele, M., De Vlieghere, E., Limame, R., Braems, G., Bracke, M., Denys, H., Libbrecht, L., De Wever, O.

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Stromal protein expression in breast cancer is differentially regulated by TGF- 1 by Van Bockstal, M., Lambein, K., Van Gele, M., De Vlieghere, E., Limame, R., Braems, G., Bracke, M., Denys, H., Libbrecht, L., De Wever, O.

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Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas by Van Gele, M, Van Roy, N, Ronan, SG, Messiaen, L, Vandesompele, J, Geerts, ML, Naeyaert, M, Blennow, E, Bar-Am, I, Das Gupta, TK, van der Drift, P, Versteeg, R, Leonard, JH, Speleman, F

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Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily by Steele-Perkins, G, Fang, W, Yang, X H, Van Gele, M, Carling, T, Gu, J, Buyse, I M, Fletcher, J A, Liu, J, Bronson, R, Chadwick, R B, de la Chapelle, A, Zhang, X, Speleman, F, Huang, S

“…The retinoblastoma protein-interacting zinc finger gene RIZ (PRDM2) is a member, by sequence homology, of a nuclear protein-methyltransferase (MTase)…”
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