Search Results - "Van Elssen, Catharina H.M.J"

The Effect of Vitamin C (Ascorbic Acid) in the Treatment of Patients with Cancer: A Systematic Review by van Gorkom, Gwendolyn N Y, Lookermans, Eline L, Van Elssen, Catharina H M J, Bos, Gerard M J

“…Many cancer patients on intensive chemotherapy lack vitamin C. Vitamin C stimulates the production and activation of immune cells, so perhaps supplementation…”
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Pathogen-Associated Molecular Patterns Induced Crosstalk between Dendritic Cells, T Helper Cells, and Natural Killer Helper Cells Can Improve Dendritic Cell Vaccination by Bos, Gerard M. J., Van Elssen, Catharina H. M. J., Vanderlocht, Joris, Oth, Tammy, Germeraad, Wilfred T. V.

“…A coordinated cellular interplay is of crucial importance in both host defense against pathogens and malignantly transformed cells. The various interactions of…”
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Klebsiella pneumoniae‐triggered DC recruit human NK cells in a CCR5‐dependent manner leading to increased CCL19‐responsiveness and activation of NK cells by Van Elssen, Catharina H.M.J, Vanderlocht, Joris, Frings, Peter W.H, Senden‐Gijsbers, Birgit L.M.G, Schnijderberg, Melanie C.A, van Gelder, Michel, Meek, Bob, Libon, Christine, Ferlazzo, Guido, Germeraad, Wilfred T.V, Bos, Gerard M.J

“…Besides their role in destruction of altered self‐cells, NK cells have been shown to potentiate T‐cell responses by interacting with DC. To take advantage of…”
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Elimination of the chemotherapy resistant subpopulation of 4T1 mouse breast cancer by haploidentical NK cells cures the vast majority of mice by Frings, Peter W. H., Van Elssen, Catharina H. M. J., Wieten, Lotte, Matos, Catarina, Hupperets, Pierre S. J. G., Schouten, Harry C., Bos, Gerard M. J., van Gelder, Michel

“…Metastatic breast cancer is currently incurable despite initial responsiveness, assumingly due to the presence of chemoresistant subpopulations that can be…”
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Flow cytometry-based assay to evaluate human serum MUC1-Tn antibodies by Van Elssen, Catharina H.M.J., Clausen, Henrik, Germeraad, Wilfred T.V., Bennet, Eric P., Menheere, Paul P., Bos, Gerard M.J., Vanderlocht, Joris

“…Mucin-1 (MUC1) is a heavily O-glycosylated, transmembrane protein that is expressed on the apical surface of most secretory epithelia. In malignantly…”
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Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease by Van Elssen, Catharina H M J, Rashidian, Mohammad, Vrbanac, Vladimir, Wucherpfennig, Kai W, Habre, Zeina El, Sticht, Jana, Freund, Christian, Jacobsen, Johanne T, Cragnolini, Juanjo, Ingram, Jessica, Plaisier, Loes, Spierings, Eric, Tager, Andrew M, Ploegh, Hidde L

“…The immune system plays a crucial role in many diseases. Activation or suppression of immunity is often related to clinical outcome. Methods to explore the…”
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NK cell alloreactivity in acute myeloid leukemia in the post‐transplant cyclophosphamide era by Van Elssen, Catharina H. M. J., Ciurea, Stefan O.

“…Allogeneic hematopoietic stem cell transplantation (alloSCT) for myeloid leukemia remains one of the most effective anti‐tumor treatments available, capable of…”
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Risk Stratification in Older Intensively Treated Patients With AML by Versluis, Jurjen, Metzner, Marlen, Wang, Ariel, Gradowska, Patrycja, Thomas, Abin, Jakobsen, Niels Asger, Kennedy, Alison, Moore, Rachel, Boertjes, Emma, Vonk, Christian M, Kavelaars, Francois G, Rijken, Melissa, Gilkes, Amanda, Schwab, Claire, Beverloo, H Berna, Manz, Markus, Visser, Otto, Van Elssen, Catharina H M J, de Weerdt, Okke, Tick, Lidwine W, Biemond, Bart J, Vekemans, Marie-Christiane, Freeman, Sylvie D, Harrison, Christine J, Cook, Jonathan A, Dennis, Mike, Knapper, Steven, Thomas, Ian, Craddock, Charles, Ossenkoppele, Gert J, Löwenberg, Bob, Russell, Nigel, Valk, Peter J M, Vyas, Paresh

“…AML is a genetically heterogeneous disease, particularly in older patients. In patients older than 60 years, survival rates are variable after the most…”
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Targeted antigen delivery by an anti-class II MHC VHH elicits focused αMUC1(Tn) immunity by Fang, Tao, Van Elssen, Catharina H M J, Duarte, Joao N, Guzman, Jonathan S, Chahal, Jasdave S, Ling, Jingjing, Ploegh, Hidde L

“…Unusual patterns of glycosylation on the surface of transformed cells contribute to immune modulation and metastasis of malignant tumors. Active immunization…”
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Increased CD8 T‐cell immunity after COVID‐19 vaccination in lymphoid malignancy patients lacking adequate humoral response: An immune compensation mechanism? by Boerenkamp, Lara S., Pothast, Cilia R., Dijkland, Romy C., Dijk, Kayleigh, Gorkom, Gwendolyn N. Y., Loo, Inge H. M., Wieten, Lotte, Halkes, Constantijn J. M., Heemskerk, Mirjam H. M., Van Elssen, Catharina H. M. J.

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Natural Killer Cells: The Secret Weapon in Dendritic Cell Vaccination Strategies by VAN ELSSEN, Catharina H. M. J, OTH, Tammy, GERMERAAD, Wilfred T. V, BOS, Gerard M. J, VANDERLOCHT, Joris

“…In cancer therapy, dendritic cell (DC) vaccination is still being explored. Clinical responses, however, are diverse and there is a lack of immunologic readout…”
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Influence of Vitamin C on Lymphocytes: An Overview by van Gorkom, Gwendolyn N Y, Klein Wolterink, Roel G J, Van Elssen, Catharina H M J, Wieten, Lotte, Germeraad, Wilfred T V, Bos, Gerard M J

“…Vitamin C or ascorbic acid (AA) is implicated in many biological processes and has been proposed as a supplement for various conditions, including cancer. In…”
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NK cell therapy after hematopoietic stem cell transplantation: can we improve anti-tumor effect? by Van Elssen, Catharina H. M. J., Ciurea, Stefan O.

“…After decades since the discovery of natural killer (NK) cells as potential effector cells fighting malignantly transformed and virally infected cells, little…”
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Addition of lenalidomide to intensive treatment in younger and middle-aged adults with newly diagnosed AML: the HOVON-SAKK-132 trial by Löwenberg, Bob, Pabst, Thomas, Maertens, Johan, Gradowska, Patrycja, Biemond, Bart J., Spertini, Olivier, Vellenga, Edo, Griskevicius, Laimonas, Tick, Lidwine W., Jongen-Lavrencic, Mojca, van Marwijk Kooy, Marinus, Vekemans, Marie-Christiane, van der Velden, Walter J.F.M., Beverloo, Berna, Michaux, Lucienne, Graux, Carlos, Deeren, Dries, de Weerdt, Okke, van Esser, Joost W.J., Bargetzi, Mario, Klein, Saskia K., Gadisseur, Alain, Westerweel, Peter E., Veelken, Hendrik, Gregor, Michael, Silzle, Tobias, van Lammeren-Venema, Daniëlle, Moors, Ine, Breems, Dimitri A., Hoogendoorn, Mels, Legdeur, Marie-Cecile J.C., Fischer, Thomas, Kuball, Juergen, Cornelissen, Jan, Porkka, Kimmo, Juliusson, Gunnar, Meyer, Peter, Höglund, Martin, Gjertsen, Bjorn T., Janssen, Jeroen J.W.M., Huls, Gerwin, Passweg, Jakob, Cloos, Jacqueline, Valk, Peter J.M., van Elssen, Catharina H.M.J., Manz, Markus G., Floisand, Yngvar, Ossenkoppele, Gert J.

“…Lenalidomide, an antineoplastic and immunomodulatory drug, has therapeutic activity in acute myeloid leukemia (AML), but definitive studies about its…”
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No Effect of Vitamin C Administration on Neutrophil Recovery in Autologous Stem Cell Transplantation for Myeloma or Lymphoma: A Blinded, Randomized Placebo-Controlled Trial by van Gorkom, Gwendolyn N Y, Boerenkamp, Lara S, Gijsbers, Birgit L M G, van Ojik, Heidi H, Wodzig, Will K W H, Wieten, Lotte, Van Elssen, Catharina H M J, Bos, Gerard M J

“…Vitamin C is an important micronutrient for various immune cells. It increases phagocytic cell function and is necessary for T and natural killer (NK) cell…”
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A randomised controlled phase II trial of pre-operative celecoxib treatment reveals anti-tumour transcriptional response in primary breast cancer by Brandão, Rita D, Veeck, Jürgen, Van de Vijver, Koen K, Lindsey, Patrick, de Vries, Bart, van Elssen, Catharina H M J, Blok, Marinus J, Keymeulen, Kristien, Ayoubi, Torik, Smeets, Hubert J M, Tjan-Heijnen, Vivianne C, Hupperets, Pierre S

“…Cyclooxygenase-2 (COX-2) is frequently over-expressed in primary breast cancer. In transgenic breast cancer models, over-expression of COX-2 leads to tumour…”
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Low Levels of Serum and Intracellular Vitamin C in Hospitalized COVID-19 Patients by Boerenkamp, Lara S, Gijsbers, Birgit L M G, Ververs, Erik-Jan, Pijpers, Eva M S, Spaetgens, Bart, de Coninck, Aniek, Germeraad, Wilfred T V, Wodzig, Will K W H, Wieten, Lotte, van Gorkom, Gwendolyn N Y, van Elssen, Catharina H M J

“…Vitamin C is a crucial micronutrient for human immune cell function and has potent antioxidant properties. It is hypothesized that vitamin C serum levels…”
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Inflammation restraining effects of prostaglandin E2 on natural killer–dendritic cell (NK-DC) interaction are imprinted during DC maturation by Van Elssen, Catharina H.M.J., Vanderlocht, Joris, Oth, Tammy, Senden-Gijsbers, Birgit L.M.G., Germeraad, Wilfred T.V., Bos, Gerard M.J.

“…Among prostaglandins (PGs), PGE2 is abundantly expressed in various malignancies and is probably one of many factors promoting tumor growth by inhibiting tumor…”
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Bone marrow produces sufficient alloreactive natural killer (NK) cells in vivo to cure mice from subcutaneously and intravascularly injected 4T1 breast cancer by van Gelder, Michel, Vanclée, Ariane, van Elssen, Catharina H. M. J., Hupperets, Pierre, Wieten, Lotte, Bos, Gerard M.

“…Purpose Administration of 5 million alloreactive natural killer (NK) cells after low-dose chemo-irradiation cured mice of 4T1 breast cancer, supposedly dose…”
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Concordance in measurable residual disease result after first and second induction cycle in acute myeloid leukemia: An outcome- and cost-analysis by Tettero, Jesse M., Al-Badri, Waleed K. W., Ngai, Lok Lam, Bachas, Costa, Breems, Dimitri A., van Elssen, Catharina H. M. J., Fischer, Thomas, Gjertsen, Bjorn T., van Gorkom, Gwendolyn N. Y., Gradowska, Patrycja, Greuter, Marjolein J. E., Griskevicius, Laimonas, Juliusson, Gunnar, Maertens, Johan, Manz, Markus G., Pabst, Thomas, Passweg, Jakob, Porkka, Kimmo, Löwenberg, Bob, Ossenkoppele, Gert J., Janssen, Jeroen J. W. M., Cloos, Jacqueline

“…Measurable residual disease (MRD) measured using multiparameter flow-cytometry (MFC) has proven to be an important prognostic biomarker in acute myeloid…”
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