Search Results - "Van Eeden, Stephan"

Lung Macrophage Phenotypes and Functional Responses: Role in the Pathogenesis of COPD by Yamasaki, Kei, Eeden, Stephan F van

“…Lung macrophages (LMs) are essential immune effector cells that are pivotal in both innate and adaptive immune responses to inhaled foreign matter. They either…”
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Lung Macrophage Functional Properties in Chronic Obstructive Pulmonary Disease by Akata, Kentaro, van Eeden, Stephan F

“…Chronic obstructive pulmonary disease (COPD) is caused by the chronic exposure of the lungs to toxic particles and gases. These exposures initiate a persistent…”
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The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter by Miyata, Ryohei, van Eeden, Stephan F.

“…Emerging epidemiological evidence suggests that exposure to particulate matter (PM) air pollution increases the risk of cardiovascular events but the exact…”
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Macrophages-the immune effector guardians of the lung: impact of corticosteroids on their functional responses by van Eeden, Stephan F, Akata, Kentaro

“…Lung macrophages (LMs) are key immune effector cells that protect the lung from inhaled particulate matter, noxious gases and pathogens. In Chronic Obstructive…”
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Contribution of Lung Macrophages to the Inflammatory Responses Induced by Exposure to Air Pollutants by Hiraiwa, Kunihiko, van Eeden, Stephan F.

“…Large population cohort studies have indicated an association between exposure to particulate matter and cardiopulmonary morbidity and mortality. The…”
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Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures by Takiguchi, Hiroto, Yang, Chen X., Yang, Cheng Wei Tony, Sahin, Basak, Whalen, Beth A., Milne, Stephen, Akata, Kentaro, Yamasaki, Kei, Yang, Julia Shun Wei, Cheung, Chung Yan, Vander Werff, Ryan, McNagny, Kelly M., Leitao Filho, Fernando Sergio, Shaipanich, Tawimas, van Eeden, Stephan F., Obeidat, Ma’en, Leung, Janice M., Sin, Don D.

“…The classical M1/M2 polarity of macrophages may not be applicable to inflammatory lung diseases including chronic obstructive pulmonary disease (COPD) due to…”
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An air filter intervention study of endothelial function among healthy adults in a woodsmoke-impacted community by Allen, Ryan W, Carlsten, Chris, Karlen, Barbara, Leckie, Sara, van Eeden, Stephan, Vedal, Sverre, Wong, Imelda, Brauer, Michael

“…Particulate air pollution is associated with cardiovascular morbidity. One hypothesized mechanism involves oxidative stress, systemic inflammation, and…”
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Circulating levels of cell adhesion molecules and risk of cardiovascular events in obstructive sleep apnea by Peres, Bernardo U, Hirsch Allen, A. J, Daniele, Patrick, Humphries, Karin H, Taylor, Carolyn, Laher, Ismail, Almeida, Fernanda, Jen, Rachel, Sandford, Andrew J, van Eeden, Stephan F, Ayas, Najib T

“…Background Obstructive sleep apnea (OSA) patients are at increased risk of cardiovascular disease (CVD). Cell adhesion molecules (CAM) are increased in OSA and…”
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Acute Exacerbation of Chronic Obstructive Pulmonary Disease : Cardiovascular Links by Laratta, Cheryl R., van Eeden, Stephan F.

“…Chronic obstructive pulmonary disease (COPD) is a chronic, progressive lung disease resulting from exposure to cigarette smoke, noxious gases, particulate…”
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Changes in atherosclerotic plaques induced by inhalation of diesel exhaust by Bai, Ni, Kido, Takashi, Suzuki, Hisashi, Yang, Grace, Kavanagh, Terrance J, Kaufman, Joel D, Rosenfeld, Michael E, van Breemen, Cornelis, Eeden, Stephan F. van

“…Abstract Objective Exposure to particulate matter air pollution may be an independent risk factor for cardiovascular morbidity and mortality; however, the…”
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The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter by Hirota, Jeremy A., PhD, Hirota, Simon A., PhD, Warner, Stephanie M., BSc, Stefanowicz, Dorota, BSc, Shaheen, Furquan, BSc, Beck, Paul L., MD, PhD, MacDonald, Justin A., PhD, Hackett, Tillie-Louise, PhD, Sin, Don D., MD, Van Eeden, Stephan, MD, Knight, Darryl A., PhD

“…Background The airway epithelium is the first line of defense against inhaled insults and therefore must be capable of coordinating appropriate inflammatory…”
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Impact of a COPD comprehensive case management program on hospital length of stay and readmission rates by Alshabanat, Abdulmajeed, Otterstatter, Michael C, Sin, Don D, Road, Jeremy, Rempel, Carmen, Burns, Jane, van Eeden, Stephan F, FitzGerald, J M

“…COPD accounts for the highest rate of hospital admissions among major chronic diseases. COPD hospitalizations are associated with impaired quality of life,…”
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Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction by Tamagawa, Eiji, Bai, Ni, Morimoto, Kiyoshi, Gray, Claire, Mui, Tammy, Yatera, Kazuhiro, Zhang, Xuekui, Xing, Li, Li, Yuexin, Laher, Ismail, Sin, Don D, Man, S F Paul, van Eeden, Stephan F

“…Epidemiologic and animal studies have shown that exposure to particulate matter air pollution (PM) is a risk factor for the development of atherosclerosis…”
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Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea by Sandford, Andrew J, Ha, Amanda, Ngan, David A, Akhabir, Loubna, Saferali, Aabida, Fox, Nurit, Hirsch Allen, A J, Warby, Simon C, van Eeden, Stephan F, Ayas, Najib T

“…Untreated obstructive sleep apnea (OSA) patients have an increased risk of cardiovascular disease (CVD). Adhesion molecules, including soluble E-selectin…”
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Obstructive sleep apnea severity, circulating biomarkers, and cancer risk by Hirsch Allen, A J, Kendzerska, Tetyana, Bhatti, Parveen, Jen, Rachel, Myers, Renelle, Hajipour, Mohammadreza, van Eeden, Stephan F, Ayas, Najib

“…To determine whether obstructive sleep apnea (OSA) severity and/or biomarkers of inflammation/angiogenesis are associated with incident cancer in this clinical…”
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Cytokines Involved in the Systemic Inflammatory Response Induced by Exposure to Particulate Matter Air Pollutants (PM10) by van EEDEN, STEPHAN F, TAN, WAN C, SUWA, TATSUSHI, MUKAE, HIROSHI, TERASHIMA, TAKESHI, FUJII, TAKESHI, QUI, DIWEN, VINCENT, RENAUD, HOGG, JAMES C

“…Elevated levels of ambient particulate matter (PM(10)) have been associated with increased cardiopulmonary morbidity and mortality. We previously showed that…”
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Particulate matter air pollution exposure: role in the development and exacerbation of chronic obstructive pulmonary disease by Ling, Sean H, van Eeden, Stephan F

“…Due to the rapid urbanization of the world population, a better understanding of the detrimental effects of exposure to urban air pollution on chronic lung…”
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Oxidative stress in chronic obstructive pulmonary disease: a lung and systemic process by van Eeden, Stephan F, Sin, Don D

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Emergency department management of acute exacerbations of chronic obstructive pulmonary disease: factors predicting readmission by Bartels, Wiebke, Adamson, Simon, Leung, Lisa, Sin, Don D, van Eeden, Stephan F

“…Readmissions are common following acute exacerbations of chronic obstructive pulmonary disease (AECOPD) and are partially responsible for increased morbidity…”
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L-selectin and skin damage in systemic sclerosis by Dunne, James V, van Eeden, Stephan F, Keen, Kevin J

“…L-selectin ligands are induced on the endothelium of inflammatory sites. L-selectin expression on neutrophils and monocytes may mediate the primary adhesion of…”
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