Search Results - "Van Drunen, C"

Nasal hyper‐reactivity is a common feature in both allergic and nonallergic rhinitis by Segboer, C. L., Holland, C. T., Reinartz, S. M., Terreehorst, I., Gevorgyan, A., Hellings, P. W., Drunen, C. M., Fokkens, W. J.

“…Background Nasal hyper‐reactivity is an increased sensitivity of the nasal mucosa to various nonspecific stimuli. Both allergic rhinitis (AR) and nonallergic…”
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FcγRIII stimulation breaks the tolerance of human nasal epithelial cells to bacteria through cross-talk with TLR4 by Golebski, K., Hoepel, W., van Egmond, D., de Groot, E. J., Amatngalim, G. D., Beekman, J. M., Fokkens, W. J., van Drunen, C. M., den Dunnen, J.

“…The nasal cavity displays immune tolerance to commensal bacteria under homeostatic conditions, which is rapidly converted to a pro-inflammatory response upon…”
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How epithelial cells detect danger: aiding the immune response by Vroling, A.B, Fokkens, W.J, van Drunen, C.M

“…The epithelial layer occupies a strategic important location between an organisms' interior and exterior environment. Although as such it forms a physical…”
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The multi‐faceted role of allergen exposure to the local airway mucosa by Golebski, K., Röschmann, K. I. L., Toppila‐Salmi, S., Hammad, H., Lambrecht, B. N., Renkonen, R., Fokkens, W. J., Drunen, C. M.

“…Airway epithelial cells are the first to encounter aeroallergens and therefore have recently become an interesting target of many studies investigating their…”
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Endothelial L-selectin ligand expression in nasal polyps by Ebbens, F.A, Toppila-Salmi, S.K, Renkonen, J.A, Renkonen, R.L.O, Mullol, J, van Drunen, C.M, Fokkens, W.J

“…L-selectins on leukocytes and their counter-receptors on endothelial cells have been shown to be involved in leukocyte recruitment in chronic rhinosinusitis…”
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Executive summary of European Task Force document on diagnostic tools in rhinology by HELLINGS, P. W, SCADDING, G, MULLOL, J, PASSALACQUA, G, TOSKALA, E, DRUNEN, C. M. Van, ALOBID, I, BACHERT, C, FOKKENS, W. J, GERTH VAN WIJK, R, GEVAERT, P, GUILEMANY, J, KALOGJERA, L, LUND, V. J

“…This Executive Summary of the EAACI Task Force document on Diagnostic Tools in Rhinology provides the readers with an over- view of the currently available…”
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Plasmacytoid dendritic cells in pulmonary lymphoid follicles of patients with COPD by VAN POTTELBERGE, G. R, BRACKE, K. R, VAN DEN BROECK, S, REINARTZ, S. M, VAN DRUNEN, C. M, WOUTERS, E. F, VERLEDEN, G. M, VERMASSEN, F. E, JOOS, G. F, BRUSSELLE, G. G

“…Plasmacytoid dendritic cells (pDCs) are professional antigen-presenting cells with antiviral and tolerogenic capabilities. Viral infections and autoimmunity…”
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Timothy grass pollen extract-induced gene expression and signalling pathways in airway epithelial cells by Röschmann, K I. L., Luiten, S., Jonker, M. J., Breit, T. M., Fokkens, W. J., Petersen, A., van Drunen, C. M.

“…Cite this as: K. I. L. Röschmann, S. Luiten, M. J. Jonker, T. M. Breit, W. J. Fokkens, A. Petersen and C. M. van Drunen, Clinical & Experimental Allergy, 2011…”
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Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway by Vroling, A.B, Jonker, M.J, Breit, T.M, Fokkens, W.J, Drunen, C.M. van

“…Airway epithelial cells have shown to be active participants in the defense against pathogens by producing signaling and other regulatory molecules in response…”
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The association of asthma, nasal allergies, and positive skin prick tests with obesity, leptin, and adiponectin by Newson, R. B., Jones, M., Forsberg, B., Janson, C., Bossios, A., Dahlen, S.-E., Toskala, E. M., Al-Kalemji, A., Kowalski, M. L., Rymarczyk, B., Salagean, E. M., van Drunen, C. M., Bachert, C., Wehrend, T., Krämer, U., Mota-Pinto, A., Burney, P., Leynaert, B., Jarvis, D.

“…Summary Background Cross‐sectional and longitudinal reports show that obese adults have more asthma than non‐obese adults. A proposed mechanism is via effects…”
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Important research questions in allergy and related diseases: 3-chronic rhinosinusitis and nasal polyposis - a GALEN study by Bachert, C, Van Bruaene, N, Toskala, E, Zhang, N, Olze, H, Scadding, G, Van Drunen, C M, Mullol, J, Cardell, L, Gevaert, P, Van Zele, T, Claeys, S, Halldén, C, Kostamo, K, Foerster, U, Kowalski, M, Bieniek, K, Olszewska-Ziaber, A, Nizankowska-Mogilnicka, E, Szczeklik, A, Swierczynska, M, Arcimowicz, M, Lund, V, Fokkens, W, Zuberbier, T, Akdis, C, Canonica, G, Van Cauwenberge, P, Burney, P, Bousquet, J

“…Chronic rhinosinusitis is one of the most common health care challenges, with significant direct medical costs and severe impact on lower airway disease and…”
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Allergen induced gene expression of airway epithelial cells shows a possible role for TNF‐α by Vroling, A. B., Duinsbergen, D., Fokkens, W. J., Van Drunen, C. M.

“…Background:  Epithelium is more than a physical barrier for pathogens and allergens, as it is also capable of producing mediators in response to these…”
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Nebulized bacitracin/colimycin : a treatment option in recalcitrant chronic rhinosinusitis with Staphylococcus aureus? A double-blind, randomized, placebo-controlled, cross-over pilot study by VIDELER, W. J. M, VAN DRUNEN, C. M, REITSMA, J. B, FOKKENS, W. J

“…Despite optimal medical therapy and endoscopic sinus surgery there still remains a group of unfortunate patients suffering from exacerbations of recalcitrant…”
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Purified Timothy grass pollen major allergen Phl p 1 may contribute to the modulation of allergic responses through a pleiotropic induction of cytokines and chemokines from airway epithelial cells by Röschmann, K. I. L., van Kuijen, A.‐M., Luiten, S., Jonker, M. J., Breit, T. M., Fokkens, W. J., Petersen, A., van Drunen, C. M.

“…Summary By definition, allergens are proteins with the ability to elicit powerful T helper lymphocyte type 2 (Th2) responses, culminating in immunoglobulin…”
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Osteitic bone in recalcitrant chronic rhinosinusitis by VIDELER, W. J. M, GEORGALAS, C, MENGER, D. J, FRELING, N. J. M, VAN DRUNEN, C. M, FOKKENS, W. J

“…There is increasing interest in the underlying bone of the paranasal sinuses as an important player in recalcitrant Chronic Rhinosinusitis. Close inspection of…”
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Expression profiling and functional analysis of Toll‐like receptors in primary healthy human nasal epithelial cells shows no correlation and a refractory LPS response by Tongeren, J., Röschmann, K. I. L., Reinartz, S. M., Luiten, S., Fokkens, W. J., Jong, E. C., Drunen, C. M.

“…Background Innate immune recognition via Toll‐like receptors (TLRs) on barrier cells like epithelial cells has been shown to influence the regulation of local…”
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Nasal polyposis: a cellular-based approach to answering questions by Rinia, A.B, Kostamo, K, Ebbens, F.A, van Drunen, C.M, Fokkens, W.J

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Interactions between epithelial cells and dendritic cells in airway immune responses: lessons from allergic airway disease by van Tongeren, J, Reinartz, S.M, Fokkens, W.J, de Jong, E.C, van Drunen, C.M

“…Micro-organisms constantly invade the human body and may form a threat to our health. Traditionally, concepts of defence mechanisms have included a protective…”
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Nasal endothelial interleukin-10 expression is negatively correlated with nasal symptoms after allergen provocation by Muller, B, de Groot, E.J.J, Kortekaas, I.J.M, Fokkens, W.J, van Drunen, C.M

“…Despite major efforts, factors that predict or correspond to the level of allergic symptoms remain elusive. Given our previous observations of mucosal…”
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Predictors of post-operative response to treatment: a double blind placebo controlled study in chronic rhinosinusitis patients by EBBENS, F. A, TOPPILA-SALMI, S, DE GROOT, E. J. J, RENKONEN, J, RENKONEN, R, VAN DRUNEN, C. M, DIJKGRAAF, M. G. W, FOKKENS, W. J

“…In the majority of CRS patients suffering from primary or recurrent CRS, topical glucocorticoids are highly effective. A subset of CRS patients, however, does…”
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