Search Results - "Van Driesche, Sarah J"

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    FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism by Darnell, Jennifer C., Van Driesche, Sarah J., Zhang, Chaolin, Hung, Ka Ying Sharon, Mele, Aldo, Fraser, Claire E., Stone, Elizabeth F., Chen, Cynthia, Fak, John J., Chi, Sung Wook, Licatalosi, Donny D., Richter, Joel D., Darnell, Robert B.

    Published in Cell (22-07-2011)
    “…FMRP loss of function causes Fragile X syndrome (FXS) and autistic features. FMRP is a polyribosome-associated neuronal RNA-binding protein, suggesting that it…”
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    Journal Article
  2. 2

    FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory by Sawicka, Kirsty, Hale, Caryn R, Park, Christopher Y, Fak, John J, Gresack, Jodi E, Van Driesche, Sarah J, Kang, Jin Joo, Darnell, Jennifer C, Darnell, Robert B

    Published in eLife (20-12-2019)
    “…Loss of the RNA binding protein FMRP causes Fragile X Syndrome (FXS), the most common cause of inherited intellectual disability, yet it is unknown how FMRP…”
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    Journal Article
  3. 3

    Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes by Steward, Oswald, Farris, Shannon, Pirbhoy, Patricia S, Darnell, Jennifer, Driesche, Sarah J Van

    Published in Frontiers in molecular neuroscience (12-01-2015)
    “…Arc is a unique immediate early gene whose expression is induced as synapses are being modified during learning. The uniqueness comes from the fact that newly…”
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  4. 4

    New frontiers in RNA transport and local translation in neurons by Van Driesche, Sarah J., Martin, Kelsey C.

    Published in Developmental neurobiology (Hoboken, N.J.) (01-03-2018)
    “…ABSTRACT RNA localization to neuronal dendrites and axons is increasingly recognized as a significant and widespread mechanism of gene expression control in…”
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