Search Results - "Van Der Werf, Tjip S"
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Therapeutic vaccines for tuberculosis—A systematic review
Published in Vaccine (30-05-2014)“…Highlights • We identified 5 potential therapeutic TB vaccines—Mycobacterium vaccae, RUTI, Mycobacterium smegmatis, Mycobacterium indicus pranii and V5. • M…”
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Sensitivity and specificity of routine diagnostic work-up for tuberculosis in lung clinics in Yogyakarta, Indonesia: a cohort study
Published in BMC public health (02-04-2019)“…Establishing a correct diagnosis is challenging. We aimed to investigate the sensitivity and specificity of routine tuberculosis (TB) diagnostic work-up in…”
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Contribution of the community health volunteers in the control of Buruli ulcer in Bénin
Published in PLoS neglected tropical diseases (01-10-2014)“…Buruli ulcer (BU) is a neglected tropical disease caused by Mycobacterium ulcerans. Usually BU begins as a painless nodule, plaque or edema, ultimately…”
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Voriconazole metabolism is influenced by severe inflammation: a prospective study
Published in Journal of antimicrobial chemotherapy (01-01-2017)“…During an infection or inflammation, several drug-metabolizing enzymes in the liver are down-regulated, including cytochrome P450 iso-enzymes. Since…”
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Global Epidemiology of Buruli Ulcer, 2010-2017, and Analysis of 2014 WHO Programmatic Targets
Published in Emerging infectious diseases (01-12-2019)“…Buruli ulcer is a neglected tropical disease caused by Myocobacterium ulcerans; it manifests as a skin lesion, nodule, or ulcer that can be extensive and…”
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Mycobacterium ulcerans disease
Published in Bulletin of the World Health Organization (01-10-2005)“…Mycobacterium ulcerans disease (Buruli ulcer) is an important health problem in several west African countries. It is prevalent in scattered foci around the…”
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Pharmacokinetics of extended-release clarithromycin in patients with Mycobacterium ulcerans infection
Published in Scientific reports (28-08-2024)“…Clarithromycin extended-release (CLA-ER) was used as companion drug to rifampicin (RIF) for Mycobacterium ulcerans infection in the intervention arm of a WHO…”
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Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection
Published in Cell reports (Cambridge) (14-03-2017)“…Recent insights into the mechanisms by which Mycobacterium tuberculosis, the etiologic agent of human tuberculosis, is recognized by cytosolic nucleotide…”
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Pathogen-based precision medicine for drug-resistant tuberculosis
Published in PLoS pathogens (01-10-2018)“…[...]mutations can be used to predict different treatment outcomes. [...]by also considering phylogenetic benign mutations that do not confer resistance, a…”
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Sensitivity and specificity of an electronic nose in diagnosing pulmonary tuberculosis among patients with suspected tuberculosis
Published in PloS one (13-06-2019)“…To investigate the potency of a hand-held point-of-care electronic-nose to diagnose pulmonary tuberculosis (PTB) among those suspected of PTB. Setting: Lung…”
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Tuberculosis-Related Malnutrition: Public Health Implications
Published in The Journal of infectious diseases (15-07-2019)Get full text
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Immunology in tuberculosis: challenges in monitoring of disease activity and identifying correlates of protection
Published in Current pharmaceutical design (01-09-2011)“…Humans have always lived with tubercle bacilli. Host susceptibility both inherited and acquired determines whether an individual infected with Mycobacterium…”
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Delayed versus standard assessment for excision surgery in patients with Buruli ulcer in Benin: a randomised controlled trial
Published in The Lancet infectious diseases (01-06-2018)“…Surgical intervention was once the mainstay of treatment for Buruli ulcer disease, a neglected tropical disease caused by Mycobacterium ulcerans. Since the…”
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Blood eosinophilia as a marker of early and late treatment failure in severe acute exacerbations of COPD
Published in Respiratory medicine (01-10-2017)“…Blood eosinophilia is frequently encountered in patients with AECOPD. However the impact of blood eosinophilia at admission in patients with AECOPD on outcome…”
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Association between Faecalibacterium prausnitzii and dietary fibre in colonic fermentation in healthy human subjects
Published in British journal of nutrition (14-09-2010)“…The intestinal microbiota are a complex ecosystem influencing the immunoregulation of the human host, providing protection from colonising pathogens and…”
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Linezolid tolerability in multidrug-resistant tuberculosis: a retrospective study
Published in The European respiratory journal (01-10-2015)“…Linezolid is used off-label to treat multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) [1, 2]. Recently, two systematic reviews…”
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Non-Steroidal Anti-inflammatory Drugs As Host-Directed Therapy for Tuberculosis: A Systematic Review
Published in Frontiers in immunology (30-06-2017)“…Lengthy, antimicrobial therapy targeting the pathogen is the mainstay of conventional tuberculosis treatment, complicated by emerging drug resistances…”
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Antimicrobial treatment for early, limited Mycobacterium ulcerans infection: a randomised controlled trial
Published in The Lancet (British edition) (20-02-2010)“…Summary Background Surgical debridement was the standard treatment for Mycobacterium ulcerans infection (Buruli ulcer disease) until WHO issued provisional…”
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Towards elimination of childhood and adolescent tuberculosis in the Netherlands: an epidemiological time-series analysis of national surveillance data
Published in The European respiratory journal (01-10-2020)“…Tuberculosis (TB) in children and adolescents is a sentinel event for ongoing transmission. In the Netherlands, epidemiological characteristics of childhood…”
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Long term streptomycin toxicity in the treatment of Buruli Ulcer: follow-up of participants in the BURULICO drug trial
Published in PLoS neglected tropical diseases (01-03-2014)“…Buruli Ulcer (BU) is a tropical infectious skin disease that is currently treated with 8 weeks of intramuscular streptomycin and oral rifampicin. As prolonged…”
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