Search Results - "Van Der Laarse, W. J."

Iron deficiency is common in idiopathic pulmonary arterial hypertension by RUITER, G, LANKHORST, S, BOONSTRA, A, POSTMUS, P. E, ZWEEGMAN, S, WESTERHOF, N, VAN DER LAARSE, W. J, VONK-NOORDEGRAAF, A

“…The aims of this study were to assess the prevalence of iron deficiency in idiopathic pulmonary arterial hypertension (IPAH) and investigate whether oral iron…”
Get full text

Depression of force production and ATPase activity in different types of human skeletal muscle fibers from patients with chronic heart failure by Szentesi, P, Bekedam, M. A, van Beek-Harmsen, B. J, van der Laarse, W. J, Zaremba, R, Boonstra, A, Visser, F. C, Stienen, G. J. M

“…Departments of 1 Physiology, 2 Cardiology, and 3 Pulmonology, Institute for Cardiovascular Research, VU Medical Center, Amsterdam, The Netherlands; and 4…”
Get full text

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism? by van Wessel, T., de Haan, A., van der Laarse, W. J., Jaspers, R. T.

“…An inverse relationship exists between striated muscle fiber size and its oxidative capacity. This relationship implies that muscle fibers, which are triggered…”
Get full text

Effects of exercise training in patients with idiopathic pulmonary arterial hypertension by de Man, F. S, Handoko, M. L, Groepenhoff, H, van 't Hul, A. J, Abbink, J, Koppers, R. J. H, Grotjohan, H. P, Twisk, J. W. R, Bogaard, H-J, Boonstra, A, Postmus, P. E, Westerhof, N, van der Laarse, W. J, Vonk-Noordegraaf, A

“…We determined the physiological effects of exercise training on exercise capacity and quadriceps muscle function in patients with idiopathic pulmonary arterial…”
Get full text

Opposite Effects of Training in Rats With Stable and Progressive Pulmonary Hypertension by HANDOKO, M. L, DE MAN, F. S, HAPPE, C. M, SCHALIJ, I, MUSTERS, R. J. P, WESTERHOF, N, POSTMUS, P. E, PAULUS, W. J, VAN DER LAARSE, W. J, VONK-NOORDEGRAAF, A

“…Exercise training in pulmonary arterial hypertension (PH) is a promising adjunct to medical treatment. However, it is still unclear whether training is…”
Get full text

Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil by MOUCHAERS, K. T. B, SCHALIJ, I, DE BOER, M. A, POSTMUS, P. E, VAN HINSBERGH, V. W. M, VAN NIEUW AMERONGEN, G. P, VONK NOORDEGRAAF, A, VAN DER LAARSE, W. J

“…Pulmonary arterial hypertension (PAH) still cannot be cured, warranting the search for novel treatments. Fasudil (a Rho kinase inhibitor) was compared with…”
Get full text

Regulation of myoglobin in hypertrophied rat cardiomyocytes in experimental pulmonary hypertension by Peters, E. L., Offringa, C., Kos, D., Van der Laarse, W. J., Jaspers, R. T.

“…A major problem in chronic heart failure is the inability of hypertrophied cardiomyocytes to maintain the required power output. A Hill-type oxygen diffusion…”
Get full text

Effects of strain on contractile force and number of sarcomeres in series of Xenopus laevis single muscle fibres during long-term culture by Jaspers, R T, Feenstra, H M, Verheyen, A K, van der Laarse, W J, Huijing, P A

“…The aim of the present study is to test whether mechanical strain uniquely regulates muscle fibre atrophy/hypertrophy and adaptation of the number of…”
Get full text

Region-specific adaptations in determinants of rat skeletal muscle oxygenation to chronic hypoxia by Wüst, R C I, Jaspers, R T, van Heijst, A F, Hopman, M T E, Hoofd, L J C, van der Laarse, W J, Degens, H

“…Chronic exposure to hypoxia is associated with muscle atrophy (i.e., a reduction in muscle fiber cross-sectional area), reduced oxidative capacity, and…”
Get more information

A refined radio-telemetry technique to monitor right ventricle or pulmonary artery pressures in rats: a useful tool in pulmonary hypertension research by Handoko, M. L., Schalij, I., Kramer, K., Sebkhi, A., Postmus, P. E., van der Laarse, W. J., Paulus, W. J., Vonk-Noordegraaf, A.

“…Implantable radio-telemetry methodology, allowing for continuous recording of pulmonary haemodynamics, has previously been used to assess effects of therapy on…”
Get full text

Adaptations in muscle oxidative capacity, fiber size, and oxygen supply capacity after repeated-sprint training in hypoxia combined with chronic hypoxic exposure by van der Zwaard, S, Brocherie, F, Kom, B L G, Millet, G P, Deldicque, L, van der Laarse, W J, Girard, O, Jaspers, R T

“…In this study, we investigate adaptations in muscle oxidative capacity, fiber size and oxygen supply capacity in team-sport athletes after six repeated-sprint…”
Get full text

Heat production and oxygen consumption during metabolic recovery of white muscle fibres from the dogfish Scyliorhinus canicula by Lou, F, van Der Laarse, W J, Curtin, N A, Woledge, R C

“…Oxygen consumption and heat production were measured during contraction and recovery of isolated, white muscle fibres from dogfish (Scyliorhinus canicula) at…”
Get full text

Energetics of small hearts by Van Der Laarse, W. J.

Get full text

Metabolic changes with fatigue in different types of single muscle fibres of Xenopus laevis by Nagesser, A S, van der Laarse, W J, Elzinga, G

“…1. Peak isometric force of single fast (type 1) and slow (type 3) muscle fibres of Xenopus decreased when fibres were stimulated intermittently above their…”
Get full text

Calibrated histochemistry applied to oxygen supply and demand in hypertrophied rat myocardium by Des Tombe, A.L., Van Beek-Harmsen, B.J., Lee-De Groot, M.B.E., Van Der Laarse, W.J.

“…Oxygen supply and demand of individual cardiomyocytes during the development of myocardial hypertrophy is studied using calibrated histochemical methods. An…”
Get full text

Effects of in vivo-like activation frequency on the length-dependent force generation of skeletal muscle fibre bundles by Zuurbier, C J, Lee-de Groot, M B, Van der Laarse, W J, Huijing, P A

“…It is known that a range of firing frequencies can be observed during in vivo muscle activity, yet information is lacking as to how different in vivo-like…”
Get full text

Myocardial force development and structural changes associated with monocrotaline induced cardiac hypertrophy and heart failure by Korstjens, I J M, Rouws, C H F C, van der Laarse, W J, Van der Zee, L, Stienen, G J M

“…In this study alterations are characterized which occur, in myocardial force development morphological appearance and protein composition, during the…”
Get full text

Fiber-specific regulation of Ca(2+)-ATPase isoform expression by thyroid hormone in rat skeletal muscle by van der Linden, C G, Simonides, W S, Muller, A, van der Laarse, W J, Vermeulen, J L, Zuidwijk, M J, Moorman, A F, van Hardeveld, C

“…We studied the effect of thyroid hormone (3,5,3'-triiodo-L-thyronine, T3) on the expression of sarcoplasmic reticulum (SR) fast- and slow-type Ca(2+)-ATPase…”
Get full text

Hypertrophy of mature Xenopus muscle fibres in culture induced by synergy of albumin and insulin by Jaspers, R. T., van Beek-Harmsen, B. J., Blankenstein, M. A., Goldspink, G., Huijing, P. A., van der Laarse, W. J.

“…The aim of this study was to investigate effects of albumin and insulin separately as well as in combination on mature muscle fibres during long-term culture…”
Get full text

ATP formation and ATP hydrolysis during fatiguing, intermittent stimulation of different types of single muscle fibres from Xenopus laevis by NAGESSER, A. S, VAN DER LAARSE, W. J, ELZINGA, G

“…This report describes changes of the rate of ATP hydrolysis in single, intact muscle fibres during the development of fatigue induced by intermittent tetanic…”
Get full text