Search Results - "Van Campenhout, Sanne"
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Angiopoietin‐2 Promotes Pathological Angiogenesis and Is a Therapeutic Target in Murine Nonalcoholic Fatty Liver Disease
Published in Hepatology (Baltimore, Md.) (01-03-2019)“…Angiogenesis contributes to the development of nonalcoholic steatohepatitis (NASH) and promotes inflammation, fibrosis, and progression to hepatocellular…”
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Body distribution of stable copper isotopes during the progression of cholestatic liver disease induced by common bile duct ligation in mice
Published in Metallomics (19-06-2019)“…Patients with chronic liver disease from different aetiologies show a light serum Cu isotopic composition compared to the reference population, with the…”
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Lighter serum copper isotopic composition in patients with early non-alcoholic fatty liver disease
Published in BMC research notes (19-04-2020)“…The occurrence of non-alcoholic fatty liver disease (NAFLD) is globally increasing. To challenge the current incidence of NAFLD, non-invasive markers that…”
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Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2019)“…Cholestatic liver disease covers a range of biliary disorders marked by an impaired bile duct flow. Various conditions can result in bile obstruction including…”
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Combination of sivelestat and N‐acetylcysteine alleviates the inflammatory response and exceeds standard treatment for acetaminophen‐induced liver injury
Published in Journal of leukocyte biology (01-02-2020)“…Hepatocyte death during acetaminophen (APAP) intoxication elicits a reactive inflammatory response, with hepatic recruitment of neutrophils and monocytes,…”
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Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model
Published in Metabolism, clinical and experimental (01-06-2020)“…Obesity, diabetes and associated non-alcoholic steatohepatitis (NASH) are rising risk factors for hepatocellular carcinoma (HCC). Macrophages are important…”
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Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis
Published in Hepatology (Baltimore, Md.) (01-02-2024)“…Primary sclerosing cholangitis (PSC) is an immune-mediated cholestatic liver disease for which pharmacological treatment options are currently unavailable. PSC…”
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Metallothioneins alter macrophage phenotype and represent novel therapeutic targets for acetaminophen‐induced liver injury
Published in Journal of leukocyte biology (01-01-2022)“…Acetaminophen (APAP) intoxication is the foremost cause of drug‐induced liver failure in developed countries. The only pharmacologic treatment option,…”
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