Search Results - "Van Bodegraven, Adriaan"
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Editorial: IBD cost evolution – transitioning from compensating lost productivity to escalating medication expenses
Published in Alimentary pharmacology & therapeutics (01-10-2023)“…LINKED CONTENT This article is linked to Everhov et al paper. To view this article, visit https://doi.org/10.1111/apt.17675…”
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Rectal swabs for analysis of the intestinal microbiota
Published in PloS one (14-07-2014)“…The composition of the gut microbiota is associated with various disease states, most notably inflammatory bowel disease, obesity and malnutrition. This…”
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Characterization of Microbiota in Children with Chronic Functional Constipation
Published in PloS one (19-10-2016)“…Disruption of the intestinal microbiota is considered an etiological factor in pediatric functional constipation. Scientifically based selection of potential…”
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Efficacy of thioguanine treatment in inflammatory bowel disease: A systematic review
Published in World journal of gastroenterology : WJG (28-10-2016)“…AIM To critically assess the available literature regarding the efficacy of thioguanine treatment in inflammatory bowel disease(IBD) patients, irrespective of…”
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Diagnosing Nodular Regenerative Hyperplasia of the Liver Is Thwarted by Low Interobserver Agreement
Published in PloS one (08-06-2015)“…Nodular regenerative hyperplasia (NRH) of the liver is associated with several diseases and drugs. Clinical symptoms of NRH may vary from absence of symptoms…”
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Genetic Analysis of Innate Immunity in Crohn's Disease and Ulcerative Colitis Identifies Two Susceptibility Loci Harboring CARD9 and IL18RAP
Published in American journal of human genetics (01-05-2008)“…The two main phenotypes of inflammatory bowel disease (IBD)—Crohn's disease (CD) and ulcerative colitis (UC)—are chronic intestinal inflammatory disorders with…”
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Predictive Algorithm for Thiopurine-Induced Hepatotoxicity in Inflammatory Bowel Disease Patients
Published in Therapeutic drug monitoring (01-12-2022)“…Approximately 25% of patients with inflammatory bowel disease (IBD) discontinue azathioprine (AZA) or mercaptopurine (MP) therapy within 3 months of treatment…”
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Diversion neovaginitis after sigmoid vaginoplasty: endoscopic and clinical characteristics
Published in Fertility and sterility (01-03-2016)“…Objective To assess the endoscopic characteristics of the sigmoid-derived neovagina, which have been scarcely described. Design Prospective observational…”
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Electronic nose can discriminate colorectal carcinoma and advanced adenomas by fecal volatile biomarker analysis: proof of principle study
Published in International journal of cancer (01-03-2014)“…In the course and prognosis of colorectal cancer (CRC), early detection and treatment are essential factors. Fecal immunochemical tests (FITs) are currently…”
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A report on the potential of Rac1/pSTAT3 protein levels in T lymphocytes to assess the pharmacodynamic effect of thiopurine therapy in Inflammatory Bowel Disease patients
Published in Scientific reports (22-09-2022)“…The thiopurine derivatives azathioprine (AZA), mercaptopurine (MP) and tioguanine (TG) remain standard treatment of inflammatory bowel disease (IBD). The…”
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The Scent of Colorectal Cancer: Detection by Volatile Organic Compound Analysis
Published in Clinical gastroenterology and hepatology (01-07-2014)“…The overall metabolic state of an individual is reflected by emitted volatile organic compounds (VOCs), which are gaseous carbon-based chemicals. In this…”
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Adalimumab for Crohn's disease: Long-term sustained benefit in a population-based cohort of 438 patients
Published in Journal of Crohn's and colitis (01-08-2014)“…Adalimumab is an effective therapy for induction and maintenance of Crohn's disease. However, results in clinical trials don't necessarily reflect daily…”
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Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2
Published in PloS one (04-08-2016)“…Genome-wide association studies have revealed several common genetic risk variants for ulcerative colitis (UC). However, little is known about the contribution…”
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Neovaginal cancer after sigmoid vaginoplasty: Implications for postoperative cancer surveillance
Published in JPRAS open (01-06-2024)“…Intestinal vaginoplasty can be performed as vaginal reconstruction procedure. Aa pedicled intestinal segment is isolated and transferred to the (neo)vaginal…”
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Therapeutic Drug Monitoring of Vedolizumab in Inflammatory Bowel Disease Patients during Maintenance Treatment-TUMMY Study
Published in Pharmaceutics (01-03-2023)“…There are limited data on therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD) patients treated with vedolizumab (VDZ). Although an…”
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Rac Attack: Modulation of the Small GTPase Rac in Inflammatory Bowel Disease and Thiopurine Therapy
Published in Molecular diagnosis & therapy (01-12-2016)“…The incidence and prevalence of inflammatory bowel disease (IBD) are increasing. Although the etiology of IBD is unknown, it is thought that genetically…”
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Retrospective analysis of old-age colitis in the Dutch inflammatory bowel disease population
Published in World journal of gastroenterology : WJG (28-05-2008)“…AIM: To describe the characteristics of Dutch patients with chronic.inflammatory bowel disease (IBD) first diagnosed above 60 years of age-a disease also known…”
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Implications of Tioguanine Dosing in IBD Patients with a TPMT Deficiency
Published in Metabolites (01-10-2023)“…Tioguanine is metabolised by fewer enzymatic steps compared to azathioprine and mercaptopurine, without generating 6-methylmercaptopurine ribonucleotides…”
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Bone loss in patients with inflammatory bowel disease: cause, detection and treatment
Published in Current opinion in gastroenterology (01-03-2021)“…Inflammatory bowel disease (IBD) is associated with bone loss leading to osteoporosis and increased fracture risk. Bone loss is the result of changes in the…”
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Classic drugs in the time of new drugs: real‐world, long‐term outcomes of thiopurine monotherapy in 1016 patients with inflammatory bowel disease
Published in Alimentary pharmacology & therapeutics (01-09-2022)“…Summary Background Thiopurines remain recommended as maintenance therapy in patients with inflammatory bowel disease (IBD). Despite their widespread use,…”
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