Search Results - "Van Bockstaele, Femke"
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Lipoprotein Lipase mRNA Expression in Whole Blood Is a Prognostic Marker in B Cell Chronic Lymphocytic Leukemia
Published in Clinical chemistry (Baltimore, Md.) (01-02-2007)“…Chronic lymphocytic leukemia (CLL) is characterized by high individual variability in clinical course and the need for therapy. Differentiation of prognostic…”
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Prognostic markers in chronic lymphocytic leukemia: A comprehensive review
Published in Blood reviews (01-01-2009)“…Summary The clinical course of individual CLL patients is highly variable, with life expectancies ranging from months to decades. Importantly, a significant…”
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Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs
Published in Blood (21-07-2011)“…Neutralizing the interaction of the platelet receptor gpIb with VWF is an attractive strategy to treat and prevent thrombotic complications. ALX-0081 is a…”
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The development of nanobodies for therapeutic applications
Published in Current opinion in investigational drugs (London, England : 2000) (01-11-2009)“…Evolution has been continuously honing the design of antibodies to function as specific molecular markers that are able to alert the immune system to the…”
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Steroid effects on ZAP-70 and SYK in relation to apoptosis in poor prognosis chronic lymphocytic leukemia
Published in Leukemia research (01-10-2009)“…Abstract There is resurgent interest in glucocorticoids (GCs) in the treatment of poor prognosis chronic lymphocytic leukemia (CLL). Little is known however on…”
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Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Anti-Vwf Nanobody® ALX-0681 After Single and Multiple Subcutaneous Administrations to Healthy Volunteers
Published in Blood (20-11-2009)“…Abstract 1063 Poster Board I-85 ALX-0681 is a humanized bivalent Nanobody®, that binds to the A1 domain of von Willebrand factor (vWF) and hence blocks its…”
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Kolmogorov–Smirnov statistical test for analysis of ZAP‐70 expression in B‐CLL, compared with quantitative PCR and IgVH mutation status
Published in Cytometry. Part B, Clinical cytometry (15-07-2006)“…Background: ZAP‐70 has been proposed as a surrogate marker for immunoglobulin heavy‐chain variable region (IgVH) mutation status, which is known as a…”
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The Restricted VH-Gene Usage Is of Prognostic Value in B-Cell Chronic Lymphocytic Leukemia
Published in Blood (16-11-2004)“…In B-cell chronic lymphocytic leukemia (B-CLL) the mutation status of the immunoglobulin variable heavy chain gene (VH) is known as a prognostic factor. We…”
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Kolmogorov-Smirnov statistical test for analysis of ZAP-70 expression in B-CLL, compared with quantitative PCR and IgV(H) mutation status
Published in Cytometry. Part B, Clinical cytometry (15-07-2006)“…ZAP-70 has been proposed as a surrogate marker for immunoglobulin heavy-chain variable region (IgV(H)) mutation status, which is known as a prognostic marker…”
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Kolmogorov-Smirnov statistical test for analysis of ZAP-70 expression in B- CLL, compared with quantitative PCR and IgV sub(H) mutation status
Published in Cytometry. Part B, Clinical cytometry (01-01-2006)“…Background:: ZAP-70 has been proposed as a surrogate marker for immunoglobulin heavy-chain variable region (IgV sub(H)) mutation status, which is known as a…”
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