Search Results - "Van Bakel, Harm"

Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer by Aydillo, Teresa, Gonzalez-Reiche, Ana S, Aslam, Sadaf, van de Guchte, Adriana, Khan, Zenab, Obla, Ajay, Dutta, Jayeeta, van Bakel, Harm, Aberg, Judith, García-Sastre, Adolfo, Shah, Gunjan, Hohl, Tobias, Papanicolaou, Genovefa, Perales, Miguel-Angel, Sepkowitz, Kent, Babady, N. Esther, Kamboj, Mini

“…The prolonged contagious period after viral infection in immunocompromised patients may affect how long precautions will be necessary to reduce further…”
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Determination and inference of eukaryotic transcription factor sequence specificity by Weirauch, Matthew T, Yang, Ally, Albu, Mihai, Cote, Atina G, Montenegro-Montero, Alejandro, Drewe, Philipp, Najafabadi, Hamed S, Lambert, Samuel A, Mann, Ishminder, Cook, Kate, Zheng, Hong, Goity, Alejandra, van Bakel, Harm, Lozano, Jean-Claude, Galli, Mary, Lewsey, Mathew G, Huang, Eryong, Mukherjee, Tuhin, Chen, Xiaoting, Reece-Hoyes, John S, Govindarajan, Sridhar, Shaulsky, Gad, Walhout, Albertha J M, Bouget, François-Yves, Ratsch, Gunnar, Larrondo, Luis F, Ecker, Joseph R, Hughes, Timothy R

“…Transcription factor (TF) DNA sequence preferences direct their regulatory activity, but are currently known for only ∼1% of eukaryotic TFs. Broadly sampling…”
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Large-Scale Genetic Perturbations Reveal Regulatory Networks and an Abundance of Gene-Specific Repressors by Kemmeren, Patrick, Sameith, Katrin, van de Pasch, Loes A.L., Benschop, Joris J., Lenstra, Tineke L., Margaritis, Thanasis, O’Duibhir, Eoghan, Apweiler, Eva, van Wageningen, Sake, Ko, Cheuk W., van Heesch, Sebastiaan, Kashani, Mehdi M., Ampatziadis-Michailidis, Giannis, Brok, Mariel O., Brabers, Nathalie A.C.H., Miles, Anthony J., Bouwmeester, Diane, van Hooff, Sander R., van Bakel, Harm, Sluiters, Erik, Bakker, Linda V., Snel, Berend, Lijnzaad, Philip, van Leenen, Dik, Groot Koerkamp, Marian J.A., Holstege, Frank C.P.

“…To understand regulatory systems, it would be useful to uniformly determine how different components contribute to the expression of all other genes. We…”
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Origins of the 2009 H1N1 influenza pandemic in swine in Mexico by Mena, Ignacio, Nelson, Martha I, Quezada-Monroy, Francisco, Dutta, Jayeeta, Cortes-Fernández, Refugio, Lara-Puente, J Horacio, Castro-Peralta, Felipa, Cunha, Luis F, Trovão, Nídia S, Lozano-Dubernard, Bernardo, Rambaut, Andrew, van Bakel, Harm, García-Sastre, Adolfo

“…Asia is considered an important source of influenza A virus (IAV) pandemics, owing to large, diverse viral reservoirs in poultry and swine. However, the…”
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Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19 by Britton, Graham J., Chen-Liaw, Alice, Cossarini, Francesca, Livanos, Alexandra E., Spindler, Matthew P., Plitt, Tamar, Eggers, Joseph, Mogno, Ilaria, Gonzalez-Reiche, Ana S., Siu, Sophia, Tankelevich, Michael, Grinspan, Lauren Tal, Dixon, Rebekah E., Jha, Divya, van de Guchte, Adriana, Khan, Zenab, Martinez-Delgado, Gustavo, Amanat, Fatima, Hoagland, Daisy A., tenOever, Benjamin R., Dubinsky, Marla C., Merad, Miriam, van Bakel, Harm, Krammer, Florian, Bongers, Gerold, Mehandru, Saurabh, Faith, Jeremiah J.

“…Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to…”
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Single-cell analysis identifies a key role for Hhip in murine coronal suture development by Holmes, Greg, Gonzalez-Reiche, Ana S., Saturne, Madrikha, Motch Perrine, Susan M., Zhou, Xianxiao, Borges, Ana C., Shewale, Bhavana, Richtsmeier, Joan T., Zhang, Bin, van Bakel, Harm, Jabs, Ethylin Wang

“…Craniofacial development depends on formation and maintenance of sutures between bones of the skull. In sutures, growth occurs at osteogenic fronts along the…”
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Reconstruction of a Functional Human Gene Network, with an Application for Prioritizing Positional Candidate Genes by Franke, Lude, Bakel, Harm van, Fokkens, Like, de Jong, Edwin D., Egmont-Petersen, Michael, Wijmenga, Cisca

“…Most common genetic disorders have a complex inheritance and may result from variants in many genes, each contributing only weak effects to the disease…”
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Avian H6 Influenza Viruses in Vietnamese Live Bird Markets during 2018-2021 by Guan, Lizheng, Babujee, Lavanya, Presler, Robert, Pattinson, David, Nguyen, Hang Le Khanh, Hoang, Vu Mai Phuong, Le, Mai Quynh, Bakel, Harm van, Kawaoka, Yoshihiro, Neumann, Gabriele

“…Avian influenza viruses of the H6 subtype are prevalent in wild ducks and likely play an important role in the ecology of influenza viruses through…”
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Molecular evidence of SARS-CoV-2 in New York before the first pandemic wave by Hernandez, Matthew M., Gonzalez-Reiche, Ana S., Alshammary, Hala, Fabre, Shelcie, Khan, Zenab, van De Guchte, Adriana, Obla, Ajay, Ellis, Ethan, Sullivan, Mitchell J., Tan, Jessica, Alburquerque, Bremy, Soto, Juan, Wang, Ching-Yi, Sridhar, Shwetha Hara, Wang, Ying-Chih, Smith, Melissa, Sebra, Robert, Paniz-Mondolfi, Alberto E., Gitman, Melissa R., Nowak, Michael D., Cordon-Cardo, Carlos, Luksza, Marta, Krammer, Florian, van Bakel, Harm, Simon, Viviana, Sordillo, Emilia Mia

“…Numerous reports document the spread of SARS-CoV-2, but there is limited information on its introduction before the identification of a local case. This may…”
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Fission Yeast Cdk7 Controls Gene Expression through both Its CAK and C-Terminal Domain Kinase Activities by Devos, Maxime, Mommaerts, Elise, Migeot, Valerie, van Bakel, Harm, Hermand, Damien

“…Cyclin-dependent kinase (Cdk) activation and RNA polymerase II transcription are linked by the Cdk7 kinase, which phosphorylates Cdks as a trimeric…”
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A humanized MDCK cell line for the efficient isolation and propagation of human influenza viruses by Takada, Kosuke, Kawakami, Chiharu, Fan, Shufang, Chiba, Shiho, Zhong, Gongxun, Gu, Chunyang, Shimizu, Kohei, Takasaki, Sara, Sakai-Tagawa, Yuko, Lopes, Tiago J. S., Dutta, Jayeeta, Khan, Zenab, Kriti, Divya, van Bakel, Harm, Yamada, Shinya, Watanabe, Tokiko, Imai, Masaki, Kawaoka, Yoshihiro

“…Here, we developed hCK, a Madin-Darby canine kidney (MDCK) cell line that expresses high levels of human influenza virus receptors and low levels of avian…”
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Identification and Characterization of Novel Antibody Epitopes on the N2 Neuraminidase by Kirkpatrick Roubidoux, Ericka, McMahon, Meagan, Carreño, Juan Manuel, Capuano, Christina, Jiang, Kaijun, Simon, Viviana, van Bakel, Harm, Wilson, Patrick, Krammer, Florian

“…The influenza virus neuraminidase (NA) is becoming a focus for novel vaccine designs. However, the epitopes of human anti-NA antibodies have been poorly…”
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Timing of Transcriptional Quiescence during Gametogenesis Is Controlled by Global Histone H3K4 Demethylation by Xu, Mengshu, Soloveychik, Maria, Ranger, Mathieu, Schertzberg, Michael, Shah, Zarna, Raisner, Ryan, Venkatasubrahmanyan, Shivkumar, Tsui, Kyle, Gebbia, Marinella, Hughes, Tim, van Bakel, Harm, Nislow, Corey, Madhani, Hiten D., Meneghini, Marc D.

“…Gametes are among the most highly specialized cells produced during development. Although gametogenesis culminates in transcriptional quiescence in plants and…”
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Cdk11-CyclinL Controls the Assembly of the RNA Polymerase II Mediator Complex by Drogat, Julie, Migeot, Valérie, Mommaerts, Elise, Mullier, Caroline, Dieu, Marc, van Bakel, Harm, Hermand, Damien

“…The large Mediator (L-Mediator) is a general coactivator of RNA polymerase II transcription and is formed by the reversible association of the small Mediator…”
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Response to “The Reality of Pervasive Transcription” by van Bakel, Harm, Nislow, Corey, Blencowe, Benjamin J, Hughes, Timothy R

“…[...]we demonstrate that conclusions very similar to those of our original study are reached with a dataset with far greater read depth, obtained by…”
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Murine Broadly Reactive Antineuraminidase Monoclonal Antibodies Protect Mice from Recent Influenza B Virus Isolates and Partially Inhibit Virus Transmission in the Guinea Pig Model by Tan, Jessica, Chromikova, Veronika, O'Dell, George, Sordillo, Emilia Mia, Simon, Viviana, van Bakel, Harm, Krammer, Florian, McMahon, Meagan

“…Current influenza virus vaccines and antivirals have limitations, some of which disproportionately affect their utilization against influenza B viruses. To…”
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Efficacy of Antibodies and Antiviral Drugs against Omicron BA.2.12.1, BA.4, and BA.5 Subvariants by Takashita, Emi, Yamayoshi, Seiya, Simon, Viviana, van Bakel, Harm, Sordillo, Emilia M., Pekosz, Andrew, Fukushi, Shuetsu, Suzuki, Tadaki, Maeda, Ken, Halfmann, Peter, Sakai-Tagawa, Yuko, Ito, Mutsumi, Watanabe, Shinji, Imai, Masaki, Hasegawa, Hideki, Kawaoka, Yoshihiro

“…In this study, investigators who were evaluating in vitro neutralization of omicron subvariants by monoclonal antibodies and antiviral drugs found considerable…”
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Immunological and Genetic Investigation of SARS-CoV-2 Reinfection in an Otherwise Healthy, Young Marine Recruit by Letizia, Andrew G, Arnold, Catherine E, Adhikari, Bishwo N, Voegtly, Logan J, Glang, Lindsay, Rice, Gregory K, Goforth, Carl W, Schilling, Megan A, Weir, Dawn L, Malagon, Francisco, Ramos, Irene, Vangeti, Sindhu, Gonzalez-Reiche, Ana S, Cer, Regina Z, Sealfon, Stuart C, van Bakel, Harm, Bishop-Lilly, Kimberly A

“…We used epidemiologic and viral genetic information to identify a case of likely reinfection in an otherwise healthy, young Marine recruit enrolled in the…”
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Activity of convalescent and vaccine serum against SARS-CoV-2 Omicron by Carreño, Juan Manuel, Alshammary, Hala, Tcheou, Johnstone, Singh, Gagandeep, Raskin, Ariel J., Kawabata, Hisaaki, Sominsky, Levy A., Clark, Jordan J., Adelsberg, Daniel C., Bielak, Dominika A., Gonzalez-Reiche, Ana Silvia, Dambrauskas, Nicholas, Vigdorovich, Vladimir, Srivastava, Komal, Sather, D. Noah, Sordillo, Emilia Mia, Bajic, Goran, van Bakel, Harm, Simon, Viviana, Krammer, Florian

“…The Omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was initially identified in November 2021 in South Africa and…”
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Introductions and early spread of SARS-CoV-2 in the New York City area by Gonzalez-Reiche, Ana S, Hernandez, Matthew M, Sullivan, Mitchell J, Ciferri, Brianne, Alshammary, Hala, Obla, Ajay, Fabre, Shelcie, Kleiner, Giulio, Polanco, Jose, Khan, Zenab, Alburquerque, Bremy, van de Guchte, Adriana, Dutta, Jayeeta, Francoeur, Nancy, Melo, Betsaida Salom, Oussenko, Irina, Deikus, Gintaras, Soto, Juan, Sridhar, Shwetha Hara, Wang, Ying-Chih, Twyman, Kathryn, Kasarskis, Andrew, Altman, Deena R, Smith, Melissa, Sebra, Robert, Aberg, Judith, Krammer, Florian, García-Sastre, Adolfo, Luksza, Marta, Patel, Gopi, Paniz-Mondolfi, Alberto, Gitman, Melissa, Sordillo, Emilia Mia, Simon, Viviana, van Bakel, Harm

“…New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the…”
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