Search Results - "Vaníkova, Jana"

Life-long correction of hyperbilirubinemia with a neonatal liver-specific AAV-mediated gene transfer in a lethal mouse model of Crigler-Najjar Syndrome by Bortolussi, Giulia, Zentillin, Lorena, Vaníkova, Jana, Bockor, Luka, Bellarosa, Cristina, Mancarella, Antonio, Vianello, Eleonora, Tiribelli, Claudio, Giacca, Mauro, Vitek, Libor, Muro, Andrés F

“…Null mutations in the UGT1A1 gene result in Crigler-Najjar syndrome type I (CNSI), characterized by severe hyperbilirubinemia and constant risk of developing…”
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Sustained reduction of hyperbilirubinemia in Gunn rats after adeno-associated virus-mediated gene transfer of bilirubin UDP-glucuronosyltransferase isozyme 1A1 to skeletal muscle by Pastore, Nunzia, Nusco, Edoardo, Vaníkova, Jana, Sepe, Rosa Maria, Vetrini, Francesco, McDonagh, Antony, Auricchio, Alberto, Vitek, Libor, Brunetti-Pierri, Nicola

“…Crigler-Najjar syndrome is an autosomal recessive disorder with severe unconjugated hyperbilirubinemia due to deficiency of bilirubin…”
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Improved efficacy and reduced toxicity by ultrasound-guided intrahepatic injections of helper-dependent adenoviral vector in Gunn rats by Pastore, Nunzia, Nusco, Edoardo, Piccolo, Pasquale, Castaldo, Sigismondo, Vaníkova, Jana, Vetrini, Francesco, Palmer, Donna J, Vitek, Libor, Ng, Philip, Brunetti-Pierri, Nicola

“…Crigler-Najjar syndrome type I is caused by mutations of the uridine diphospho-glucuronosyl transferase 1A1 (UGT1A1) gene resulting in life-threatening…”
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Anti-cancer effects of blue-green alga Spirulina platensis, a natural source of bilirubin-like tetrapyrrolic compounds by Koníčková, Renata, Vaňková, Kateřina, Vaníková, Jana, Vánová, Katerina, Muchová, Lucie, Subhanová, Iva, Zadinová, Marie, Zelenka, Jaroslav, Dvořák, Ales, Kolář, Michal, Strnad, Hynek, Rimpelová, Silvie, Ruml, Tomas, Wong, Ronald J, Vítek, Libor

“…AbstractSpirulina platensis is a blue-green alga used as a dietary supplement because of its hypocholesterolemic properties. Among other bioactive substances,…”
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Letter by Vitek et al regarding article, "niacin inhibits vascular inflammation via the induction of heme oxygenase-1" by Vítek, Libor, Vaníková, Jana, Nachtigal, Petr

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Beyond plasma bilirubin: The effects of phototherapy and albumin on brain bilirubin levels in Gunn rats by Cuperus, Frans J.C, Schreuder, Andrea B, van Imhoff, Deirdre E, Vitek, Libor, Vanikova, Jana, Konickova, Renata, Ahlfors, Charles E, Hulzebos, Christian V, Verkade, Henkjan J

“…Background & Aims Severe unconjugated hyperbilirubinemia, as occurs in Crigler–Najjar disease and neonatal jaundice, carries the risk of neurotoxicity. This…”
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Optimizing exchange transfusion for severe unconjugated hyperbilirubinemia: studies in the Gunn rat by Schreuder, Andrea B, Vanikova, Jana, Vitek, Libor, Havinga, Rick, Ahlfors, Charles E, Hulzebos, Christian V, Verkade, Henkjan J

“…Severe unconjugated hyperbilirubinemia carries the risk of neurotoxicity. Phototherapy (PT) and exchange transfusion (ET) are cornerstones in the treatment of…”
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Spirulina platensis and phycocyanobilin activate atheroprotective heme oxygenase-1: a possible implication for atherogenesis by Strasky, Zbynek, Zemankova, Lenka, Nemeckova, Ivana, Rathouska, Jana, Wong, Ronald J, Muchova, Lucie, Subhanova, Iva, Vanikova, Jana, Vanova, Katerina, Vitek, Libor, Nachtigal, Petr

“…Spirulina platensis, a water blue-green alga, has been associated with potent biological effects, which might have important relevance in atheroprotection. We…”
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Albumin administration protects against bilirubin-induced auditory brainstem dysfunction in Gunn rat pups by Schreuder, Andrea B., Rice, Ann C., Vanikova, Jana, Vitek, Libor, Shapiro, Steven M., Verkade, Henkjan J.

“…Background Free bilirubin (Bf), the unbound fraction of unconjugated bilirubin (UCB), can induce neurotoxicity, including impairment of the auditory system,…”
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