Search Results - "Van Wijmeersch, Bart"

Cytotoxic CD4+ T Cells Drive Multiple Sclerosis Progression by Peeters, Liesbet M, Vanheusden, Marjan, Somers, Veerle, Van Wijmeersch, Bart, Stinissen, Piet, Broux, Bieke, Hellings, Niels

“…Multiple sclerosis (MS) is the leading cause of chronic neurological disability in young adults. The clinical disease course of MS varies greatly between…”
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Machine learning analysis of motor evoked potential time series to predict disability progression in multiple sclerosis by Yperman, Jan, Becker, Thijs, Valkenborg, Dirk, Popescu, Veronica, Hellings, Niels, Wijmeersch, Bart Van, Peeters, Liesbet M

“…Evoked potentials (EPs) are a measure of the conductivity of the central nervous system. They are used to monitor disease progression of multiple sclerosis…”
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Cytomegalovirus infection exacerbates autoimmune mediated neuroinflammation by Vanheusden, Marjan, Broux, Bieke, Welten, Suzanne P. M., Peeters, Liesbet M., Panagioti, Eleni, Van Wijmeersch, Bart, Somers, Veerle, Stinissen, Piet, Arens, Ramon, Hellings, Niels

“…Cytomegalovirus (CMV) is a latent virus which causes chronic activation of the immune system. Here, we demonstrate that cytotoxic and pro-inflammatory CD4 +…”
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Motor evoked potentials for multiple sclerosis, a multiyear follow-up dataset by Yperman, Jan, Popescu, Veronica, Van Wijmeersch, Bart, Becker, Thijs, Peeters, Liesbet M.

“…Multiple sclerosis (MS) is a chronic disease affecting millions of people worldwide. Through the demyelinating and axonal pathology of MS, the signal…”
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Best Practices for Long-Term Monitoring and Follow-Up of Alemtuzumab-Treated MS Patients in Real-World Clinical Settings by Barclay, Krista, Carruthers, Robert, Traboulsee, Anthony, Bass, Ann D, LaGanke, Christopher, Bertolotto, Antonio, Boster, Aaron, Celius, Elisabeth G, de Seze, Jérôme, Cruz, Dionisio Dela, Habek, Mario, Lee, Jong-Mi, Limmroth, Volker, Meuth, Sven G, Oreja-Guevara, Celia, Pagnotta, Patricia, Vos, Cindy, Ziemssen, Tjalf, Baker, Darren P, Wijmeersch, Bart Van

“…Multiple sclerosis (MS) is a chronic autoimmune neurological disease that typically affects young adults, causing irreversible physical disability and…”
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CNS delivery of anti-CD52 antibodies modestly reduces disease severity in an animal model for multiple sclerosis by Bogie, Jeroen FJ, Grajchen, Elien, Wouters, Elien, Broux, Bieke, Stinissen, Piet, Van Wijmeersch, Bart, Hendriks, Jerome JA

“…Background and aims: Alemtuzumab is a humanized monoclonal antibody that depletes CD52-bearing B and T lymphocytes. Clinical trials defined that systemic…”
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The use of alemtuzumab in patients with relapsing-remitting multiple sclerosis: the Gulf perspective by Alroughani, Raed, Van Wijmeersch, Bart, Al Khaboori, Jabber, Alsharoqi, Isa Ahmed, Ahmed, Samar F., Hassan, Ali, Inshasi, Jihad, Krieger, Derk W., Shakra, Mustafa, Shatila, Ahmed Osman, Szolics, Miklos, Khallaf, Mohamed, Ezzat, Aly

“…Over the past decade, the development of high-efficacy disease-modifying therapies (DMTs) has been responsible for more effective management of…”
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Effects of an individual 12-week community-located “start-to-run” program on physical capacity, walking, fatigue, cognitive function, brain volumes, and structures in persons with multiple sclerosis by Feys, Peter, Moumdjian, Lousin, Van Halewyck, Florian, Wens, Inez, Eijnde, Bert O, Van Wijmeersch, Bart, Popescu, Veronica, Van Asch, Paul

“…Background: Exercise therapy studies in persons with multiple sclerosis (pwMS) primarily focused on motor outcomes in mid disease stage, while cognitive…”
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Efficacy and safety of ocrelizumab in patients with relapsing‐remitting multiple sclerosis with suboptimal response to prior disease‐modifying therapies: A primary analysis from the phase 3b CASTING single‐arm, open‐label trial by Vermersch, Patrick, Oreja‐Guevara, Celia, Siva, Aksel, Van Wijmeersch, Bart, Wiendl, Heinz, Wuerfel, Jens, Buffels, Regine, Kadner, Karen, Kuenzel, Thomas, Comi, Giancarlo

“…Background and purpose Using the treatment goal of “no evidence of disease activity” (NEDA) incorporating magnetic resonance imaging (MRI) re‐baselining, we…”
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Compositional changes of B and T cell subtypes during fingolimod treatment in multiple sclerosis patients: a 12-month follow-up study by Claes, Nele, Dhaeze, Tessa, Fraussen, Judith, Broux, Bieke, Van Wijmeersch, Bart, Stinissen, Piet, Hupperts, Raymond, Hellings, Niels, Somers, Veerle

“…The long term effects of fingolimod, an oral treatment for relapsing-remitting (RR) multiple sclerosis (MS), on blood circulating B and T cell subtypes in MS…”
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Comparison of fingolimod, dimethyl fumarate and teriflunomide for multiple sclerosis by Kalincik, Tomas, Kubala Havrdova, Eva, Horakova, Dana, Izquierdo, Guillermo, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grammond, Pierre, Onofrj, Marco, Lugaresi, Alessandra, Ozakbas, Serkan, Kappos, Ludwig, Kuhle, Jens, Terzi, Murat, Lechner-Scott, Jeannette, Boz, Cavit, Grand'Maison, Francois, Prevost, Julie, Sola, Patrizia, Ferraro, Diana, Granella, Franco, Trojano, Maria, Bergamaschi, Roberto, Pucci, Eugenio, Turkoglu, Recai, McCombe, Pamela A, Pesch, Vincent Van, Van Wijmeersch, Bart, Solaro, Claudio, Ramo-Tello, Cristina, Slee, Mark, Alroughani, Raed, Yamout, Bassem, Shaygannejad, Vahid, Spitaleri, Daniele, Sánchez-Menoyo, José Luis, Ampapa, Radek, Hodgkinson, Suzanne, Karabudak, Rana, Butler, Ernest, Vucic, Steve, Jokubaitis, Vilija, Spelman, Tim, Butzkueven, Helmut

“…ObjectiveOral immunotherapies have become a standard treatment in relapsing-remitting multiple sclerosis. Direct comparison of their effect on relapse and…”
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A pilot study of the effects of running training on visuospatial memory in MS: A stronger functional embedding of the hippocampus in the default-mode network? by Huiskamp, Marijn, Moumdjian, Lousin, van Asch, Paul, Popescu, Veronica, Schoonheim, Menno Michiel, Steenwijk, Martijn D, Vanzeir, Ellen, van Wijmeersch, Bart, Geurts, Jeroen JG, Feys, Peter, Hulst, Hanneke E

“…Background/objective: Endurance exercise can improve memory function in persons with multiple sclerosis (pwMS), but the effects on hippocampal functioning are…”
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Immune thrombocytopenia in alemtuzumab-treated MS patients: Incidence, detection, and management by Cuker, Adam, Bass, Ann D, Nadj, Congor, Agius, Mark A, Steingo, Brian, Selmaj, Krzysztof W, Thoits, Timothy, Guerreiro, Alexandre, Van Wijmeersch, Bart, Ziemssen, Tjalf, Meuth, Sven G, LaGanke, Christopher C, Thangavelu, Karthinathan, Rodriguez, Claudio E, Baker, Darren P, Margolin, David H, Jannsens, Ann

“…Background: Alemtuzumab is a highly effective therapy for relapsing-remitting multiple sclerosis (RRMS), and immune thrombocytopenia (ITP) has been identified…”
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Differential effects and discriminative validity of motor and cognitive tasks varying in difficulty on cognitive–motor interference in persons with multiple sclerosis by Veldkamp, Renee, Kalron, Alon, Baert, Ilse, Hämäläinen, Paivi, Tacchino, Andrea, D’hooge, Mieke, Giffroy, Xavier, Van Geel, Fanny, Raats, Joke, Coninx, Karin, Van Wijmeersch, Bart, Feys, Peter

“…Background: Cognitive–motor interference (CMI) has been well recognized in persons with multiple sclerosis (pwMS); however, there are limited data on effects…”
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Using personalized prognosis in the treatment of relapsing multiple sclerosis: A practical guide by Van Wijmeersch, Bart, Hartung, Hans-Peter, Vermersch, Patrick, Pugliatti, Maura, Pozzilli, Carlo, Grigoriadis, Nikolaos, Alkhawajah, Mona, Airas, Laura, Linker, Ralf, Oreja-Guevara, Celia

“…The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating important challenges for the neurologist to appropriately treat…”
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Perceptual super-resolution in multiple sclerosis MRI by Giraldo, Diana L., Khan, Hamza, Pineda, Gustavo, Liang, Zhihua, Lozano-Castillo, Alfonso, Van Wijmeersch, Bart, Woodruff, Henry C., Lambin, Philippe, Romero, Eduardo, Peeters, Liesbet M., Sijbers, Jan

“…Introduction Magnetic resonance imaging (MRI) is crucial for diagnosing and monitoring of multiple sclerosis (MS) as it is used to assess lesions in the brain…”
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Managing multiple sclerosis in individuals aged 55 and above: a comprehensive review by Fernández, Óscar, Sörensen, Per Soelberg, Comi, Giancarlo, Vermersch, Patrick, Hartung, Hans-Peter, Leocani, Letizia, Berger, Thomas, Van Wijmeersch, Bart, Oreja-Guevara, Celia

“…Multiple Sclerosis (MS) management in individuals aged 55 and above presents unique challenges due to the complex interaction between aging, comorbidities,…”
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Disability accrual in primary and secondary progressive multiple sclerosis by Harding-Forrester, Sam, Roos, Izanne, Nguyen, Ai-Lan, Malpas, Charles B, Diouf, Ibrahima, Moradi, Nahid, Sharmin, Sifat, Izquierdo, Guillermo, Eichau, Sara, Patti, Francesco, Horakova, Dana, Kubala Havrdova, Eva, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Grand'Maison, Francois, Onofrj, Marco, Lugaresi, Alessandra, Grammond, Pierre, Ozakbas, Serkan, Amato, Maria Pia, Gerlach, Oliver, Sola, Patrizia, Ferraro, Diana, Buzzard, Katherine, Skibina, Olga, Lechner-Scott, Jeannette, Alroughani, Raed, Boz, Cavit, Van Pesch, Vincent, Cartechini, Elisabetta, Terzi, Murat, Maimone, Davide, Ramo-Tello, Cristina, Yamout, Bassem, Khoury, Samia Joseph, La Spitaleri, Daniele, Sa, Maria Jose, Blanco, Yolanda, Granella, Franco, Slee, Mark, Butler, Ernest, Sidhom, Youssef, Gouider, Riadh, Bergamaschi, Roberto, Karabudak, Rana, Ampapa, Radek, Sánchez-Menoyo, José Luis, Prevost, Julie, Castillo-Trivino, Tamara, McCombe, Pamela A, Macdonell, Richard, Laureys, Guy, Van Hijfte, Liesbeth, Oh, Jiwon, Altintas, Ayse, de Gans, Koen, Turkoglu, Recai, van der Walt, Anneke, Butzkueven, Helmut, Vucic, Steve, Barnett, Michael, Cristiano, Edgardo, Hodgkinson, Suzanne, Iuliano, Gerardo, Kappos, Ludwig, Kuhle, Jens, Shaygannejad, Vahid, Soysal, Aysun, Weinstock-Guttman, Bianca, Van Wijmeersch, Bart, Kalincik, Tomas

“…BackgroundSome studies comparing primary and secondary progressive multiple sclerosis (PPMS, SPMS) report similar ages at onset of the progressive phase and…”
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Documenting outdoor activity and travel behaviour in persons with neurological conditions using travel diaries and GPS tracking technology: a pilot study in multiple sclerosis by Neven, An, Janssens, Davy, Alders, Geert, Wets, Geert, Wijmeersch, Bart Van, Feys, Peter

“…Abstract Objective: Persons with multiple sclerosis (PwMS) experience several physical and cognitive problems which can influence their travel behaviour. This…”
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Rapamycin rescues loss of function in blood-brain barrier-interacting Tregs by Baeten, Paulien, Hamad, Ibrahim, Hoeks, Cindy, Hiltensperger, Michael, Van Wijmeersch, Bart, Popescu, Veronica, Aly, Lilian, Somers, Veerle, Korn, Thomas, Kleinewietfeld, Markus, Hellings, Niels, Broux, Bieke

“…In autoimmunity, FOXP3+ Tregs skew toward a proinflammatory, nonsuppressive phenotype and are, therefore, unable to control the exaggerated autoimmune…”
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