Search Results - "Van Endert, Peter"

Beware the algorithm by van Endert, Peter

“…Spliced peptides present on tumor cells can help to mount an immune response, but algorithms offer limited help in predicting which ones actually exist and…”
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IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses by Evnouchidou, Irini, Chappert, Pascal, Benadda, Samira, Zucchetti, Andres, Weimershaus, Mirjana, Bens, Marcelle, Caillens, Vivien, Koumantou, Despoina, Lotersztajn, Sophie, van Endert, Peter, Davoust, Jean, Guermonprez, Pierre, Hivroz, Claire, Gross, David A., Saveanu, Loredana

“…T cell receptor (TCR) activation is modulated by mechanisms such as TCR endocytosis, which is thought to terminate TCR signalling. Here we show that, upon…”
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Anticancer Chemotherapy-Induced Intratumoral Recruitment and Differentiation of Antigen-Presenting Cells by Ma, Yuting, Adjemian, Sandy, Mattarollo, Stephen R., Yamazaki, Takahiro, Aymeric, Laetitia, Yang, Heng, Portela Catani, João Paulo, Hannani, Dalil, Duret, Helene, Steegh, Kim, Martins, Isabelle, Schlemmer, Frederic, Michaud, Mickaël, Kepp, Oliver, Sukkurwala, Abdul Qader, Menger, Laurie, Vacchelli, Erika, Droin, Nathalie, Galluzzi, Lorenzo, Krzysiek, Roman, Gordon, Siamon, Taylor, Philip R., Van Endert, Peter, Solary, Eric, Smyth, Mark J., Zitvogel, Laurence, Kroemer, Guido

“…The therapeutic efficacy of anthracyclines relies on antitumor immune responses elicited by dying cancer cells. How chemotherapy-induced cell death leads to…”
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Endocytic Recycling of MHC Class I Molecules in Non-professional Antigen Presenting and Dendritic Cells by Montealegre, Sebastian, van Endert, Peter M

“…Major histocompatibility complex class I (MHC I) molecules are glycoproteins that display peptide epitopes at the cell surface of nucleated cells for…”
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Kinesin-1 regulates antigen cross-presentation through the scission of tubulations from early endosomes in dendritic cells by Belabed, Meriem, Mauvais, François-Xavier, Maschalidi, Sophia, Kurowska, Mathieu, Goudin, Nicolas, Huang, Jian-Dong, Fischer, Alain, de Saint Basile, Geneviève, van Endert, Peter, Sepulveda, Fernando E., Ménasché, Gaël

“…Dendritic cells (DCs) constitute a specialized population of immune cells that present exogenous antigen (Ag) on major histocompatibility complex (MHC) class I…”
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Local anesthetics elicit immune-dependent anticancer effects by Bezu, Lucillia, Wu Chuang, Alejandra, Sauvat, Allan, Humeau, Juliette, Xie, Wei, Cerrato, Giulia, Liu, Peng, Zhao, Liwei, Zhang, Shuai, Le Naour, Julie, Pol, Jonathan, van Endert, Peter, Kepp, Oliver, Barlesi, Fabrice, Kroemer, Guido

“…BackgroundRetrospective clinical trials reported a reduced local relapse rate, as well as improved overall survival after injection of local anesthetics during…”
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Sex- and time-dependent role of insulin regulated aminopeptidase in lipopolysaccharide-induced inflammation by Vear, Anika, Chakraborty, Amlan, Fahimi, Farnaz, Ferens, Dorota, Widdop, Robert, Samuel, Chrishan S, Gaspari, Tracey, van Endert, Peter M, Chai, Siew Yeen

“…The enzyme, insulin regulated aminopeptidase (IRAP), is expressed in multiple immune cells such as macrophages, dendritic cells and T cells, where it plays a…”
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Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum by van Endert, Peter M, Lopez, Daniel, Greer, Fiona, Niedermann, Gabriele, Carroll, Oliver, Lindo, Vivian, Lepelletier, Yves, Fruci, Doriana, Saveanu, Loredana, Del Val, Margarita, Schomburg, Lutz

“…The generation of many HLA class I peptides entails a final trimming step in the endoplasmic reticulum that, in humans, is accomplished by two 'candidate'…”
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Role of tripeptidyl peptidase II in MHC class I antigen processing - the end of controversies by Endert, Peter van

“…Peptide ligands presented by MHC class I molecules are generated in a cascade of proteolytic events starting with the proteasome in the cytosol and frequently…”
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Liver-Primed Memory T Cells Generated under Noninflammatory Conditions Provide Anti-infectious Immunity by Böttcher, Jan P., Schanz, Oliver, Wohlleber, Dirk, Abdullah, Zeinab, Debey-Pascher, Svenja, Staratschek-Jox, Andrea, Höchst, Bastian, Hegenbarth, Silke, Grell, Jessica, Limmer, Andreas, Atreya, Imke, Neurath, Markus F., Busch, Dirk H., Schmitt, Edgar, van Endert, Peter, Kolanus, Waldemar, Kurts, Christian, Schultze, Joachim L., Diehl, Linda, Knolle, Percy A.

“…Development of CD8+ T cell (CTL) immunity or tolerance is linked to the conditions during T cell priming. Dendritic cells (DCs) matured during inflammation…”
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Editorial: Insights in antigen presenting cell biology: 2022 by van Endert, Peter

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Intracellular recycling and cross-presentation by MHC class I molecules by van Endert, Peter

“…Summary Cross‐presentation of internalized antigens by dendritic cells requires efficient delivery of Major Histocompatibility Complex (MHC) class I molecules…”
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Editorial: Insights in antigen presenting cell biology: 2021 by van Endert, Peter

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FDX2 and ISCU Gene Variations Lead to Rhabdomyolysis With Distinct Severity and Iron Regulation by Montealegre, Sebastian, Lebigot, Elise, Debruge, Hugo, Romero, Norma, Héron, Bénédicte, Gaignard, Pauline, Legendre, Antoine, Imbard, Apolline, Gobin, Stéphanie, Lacène, Emmanuelle, Nusbaum, Patrick, Hubas, Arnaud, Desguerre, Isabelle, Servais, Aude, Laforêt, Pascal, van Endert, Peter, Authier, François Jérome, Gitiaux, Cyril, de Lonlay, Pascale

“…To determine common clinical and biological traits in 2 individuals with variants in and , displaying severe and recurrent rhabdomyolyses and lactic acidosis…”
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Neuropilin-1 Is Involved in Human T-Cell Lymphotropic Virus Type 1 Entry by GHEZ, David, LEPELLETIER, Yves, HERMINE, Olivier, LAMBERT, Sophie, FOURNEAU, Jean-Marie, BLOT, Vincent, JANVIER, Sébastien, ARNULF, Bertrand, VAN ENDERT, Peter M, HEVEKER, Nikolaus, PIQUE, Claudine

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification by Tenzer, Stefan, Crawford, Hayley, Pymm, Phillip, Gifford, Robert, Sreenu, Vattipally B., Weimershaus, Mirjana, de Oliveira, Tulio, Burgevin, Anne, Gerstoft, Jan, Akkad, Nadja, Lunn, Daniel, Fugger, Lars, Bell, John, Schild, Hansjörg, van Endert, Peter, Iversen, Astrid K.N.

“…The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8+ T cell responses to two HIV-Gag…”
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Beta cell antigens in type 1 diabetes: triggers in pathogenesis and therapeutic targets [version 1; peer review: 3 approved] by Mauvais, François-Xavier, Diana, Julien, van Endert, Peter

“…Research focusing on type 1 diabetes (T1D) autoantigens aims to explore our understanding of these beta cell proteins in order to design assays for monitoring…”
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Control of cross‐presentation during dendritic cell maturation by Gil‐Torregrosa, Beatriz C., Lennon‐Duménil, Ana Maria, Kessler, Benedikt, Guermonprez, Pierre, Ploegh, Hidde L., Fruci, Doriana, Endert, Peter Van, Amigorena, Sebastian

“…The initiation of most cytotoxic immune responses requires MHC class I‐restricted presentation of internalized antigens to CD8+ T lymphocytes, a process called…”
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MHC Class I Cross-Presentation: Stage Lights on Sec22b by Montealegre, Sebastian, van Endert, Peter

“…Efficient (cross-)presentation of antigens internalized by dendritic cells (DCs) requires vesicular communication between the early secretory and the…”
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Unexpected lack of specificity of a rabbit polyclonal TAP-L (ABCB9) antibody by van Endert, Peter, Lawand, Myriam

“…In this article, we describe the surprising non-specific reactivity in immunoblots of a rabbit polyclonal antibody (ref. Abcam 86222) expected to recognize the…”
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