Search Results - "Van Den Berg, David J."
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Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA
Published in Scientific reports (17-10-2023)“…Despite the prognostic value of arterial stiffness (AS) and pulsatile hemodynamics (PH) for cardiovascular morbidity and mortality, epigenetic modifications…”
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2
Green tea intake, MTHFR/TYMS genotype and breast cancer risk: the Singapore Chinese Health Study
Published in Carcinogenesis (New York) (01-10-2008)“…The tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) has been reported to act as a cancer preventive agent through folate pathway inhibition in…”
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3
Data-adaptive multi-locus association testing in subjects with arbitrary genealogical relationships
Published in Statistical applications in genetics and molecular biology (08-04-2019)“…Genome-wide sequencing enables evaluation of associations between traits and combinations of variants in genes and pathways. But such evaluation requires…”
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4
A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32
Published in Blood (12-01-2012)“…Nodular sclerosing Hodgkin lymphoma (NSHL) is a distinct, highly heritable Hodgkin lymphoma subtype. We undertook a genome-wide meta-analysis of 393…”
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5
Snagger: a user-friendly program for incorporating additional information for tagSNP selection
Published in BMC bioinformatics (27-03-2008)“…There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not…”
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6
A genome-wide scan for breast cancer risk haplotypes among African American women
Published in PloS one (28-02-2013)“…Genome-wide association studies (GWAS) simultaneously investigating hundreds of thousands of single nucleotide polymorphisms (SNP) have become a powerful tool…”
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7
Interleukin-6-Related Genotypes, Body Mass Index, and Risk of Multiple Myeloma and Plasmacytoma
Published in Cancer epidemiology, biomarkers & prevention (01-11-2006)“…Interleukin-6 (IL-6) promotes normal plasma cell development and proliferation of myeloma cells in culture. We evaluated IL-6 genotypes and body mass index…”
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8
No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned
Published in Human molecular genetics (15-08-2008)“…The steroid 5-alpha reductase type II gene (SRD5A2) encodes the enzyme which converts testosterone (T) to the more active androgen dihydrotestosterone. A…”
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9
Epigenome-wide association study of mitochondrial genome copy number
Published in Human molecular genetics (27-12-2021)“…Abstract We conducted cohort- and race-specific epigenome-wide association analyses of mitochondrial deoxyribonucleic acid (mtDNA) copy number (mtDNA CN)…”
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10
A methylation risk score for chronic kidney disease: a HyperGEN study
Published in Scientific reports (01-08-2024)“…Chronic kidney disease (CKD) impacts about 1 in 7 adults in the United States, but African Americans (AAs) carry a disproportionately higher burden of disease…”
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11
A Genome Screen of Families with Multiple Cases of Prostate Cancer: Evidence of Genetic Heterogeneity
Published in American journal of human genetics (01-07-2001)“…We conducted a genomewide screen for prostate cancer–susceptibility genes on the basis of data from 98 families from the United States and Canada that had…”
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12
Genome-wide interaction studies reveal sex-specific asthma risk alleles
Published in Human molecular genetics (01-10-2014)“…Asthma is a complex disease with sex-specific differences in prevalence. Candidate gene studies have suggested that genotype-by-sex interaction effects on…”
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13
Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles―Shanghai bladder case―control study
Published in Carcinogenesis (New York) (01-02-2011)“…Genome-wide association studies have associated common variations at chromosomes 5p15 and 15q25 with lung cancer risk. The 5p15 locus has also been associated…”
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14
A genome-wide association study of breast cancer in women of African ancestry
Published in Human genetics (01-01-2013)“…Genome-wide association studies (GWAS) in diverse populations are needed to reveal variants that are more common and/or limited to defined populations. We…”
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15
Breast cancer susceptibility variants and mammographic density phenotypes in norwegian postmenopausal women
Published in Cancer epidemiology, biomarkers & prevention (01-09-2014)“…Mammographic density (MD) is one of the strongest known breast cancer risk factors. Twin studies have suggested that a large part of the variation in MD is…”
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16
Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer
Published in International journal of cancer (01-05-2011)“…Common germline genetic variation in the population is associated with susceptibility to epithelial ovarian cancer. Microcell‐mediated chromosome transfer and…”
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Assessment of Multifactor Gene-Environment Interactions and Ovarian Cancer Risk: Candidate Genes, Obesity, and Hormone-Related Risk Factors
Published in Cancer epidemiology, biomarkers & prevention (01-05-2016)“…Many epithelial ovarian cancer (EOC) risk factors relate to hormone exposure and elevated estrogen levels are associated with obesity in postmenopausal women…”
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Role of Members of the Wnt Gene Family in Human Hematopoiesis
Published in Blood (01-11-1998)“…The hematopoietic system is derived from ventral mesoderm. A number of genes that are important in mesoderm development have been identified including members…”
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Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users
Published in Breast cancer research : BCR (27-10-2012)“…Mammographic density (MD) is one of the strongest known breast cancer risk factors. Estrogen and progestin therapy (EPT) has been associated with increases in…”
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Reproducibility and reliability of SNP analysis using human cellular DNA at or near nanogram levels
Published in BMC research notes (06-12-2013)“…Illumina SNP arrays have been routinely used for genome-wide association studies to identify potential biomarkers for various diseases. The recommended 200 ng…”
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