Search Results - "Van, Mike"

Nanobody-mediated control of gene expression and epigenetic memory by Van, Mike V., Fujimori, Taihei, Bintu, Lacramioara

“…Targeting chromatin regulators to specific genomic locations for gene control is emerging as a powerful method in basic research and synthetic biology…”
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High-Throughput Discovery and Characterization of Human Transcriptional Effectors by Tycko, Josh, DelRosso, Nicole, Hess, Gaelen T., Aradhana, Banerjee, Abhimanyu, Mukund, Aditya, Van, Mike V., Ego, Braeden K., Yao, David, Spees, Kaitlyn, Suzuki, Peter, Marinov, Georgi K., Kundaje, Anshul, Bassik, Michael C., Bintu, Lacramioara

“…Thousands of proteins localize to the nucleus; however, it remains unclear which contain transcriptional effectors. Here, we develop HT-recruit, a pooled assay…”
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Evaluation of global optimization algorithms for parameter calibration of a computationally intensive hydrologic model by Zhang, Xuesong, Srinivasan, Raghavan, Zhao, Kaiguang, Liew, Mike Van

“…With the popularity of complex hydrologic models, the time taken to run these models is increasing substantially. Comparing and evaluating the efficacy of…”
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Whole‐slide margin control through deep learning in Mohs micrographic surgery for basal cell carcinoma by Zon, Mike C.M., Waa, José D., Veta, Mitko, Krekels, Gertruud A.M.

“…Background Basal cell carcinoma (BCC) is the most common type of skin cancer with incidence rates rising each year. Mohs micrographic surgery (MMS) is most…”
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Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma by Koopmans, Anna E, Verdijk, Robert M, Brouwer, Rutger W W, van den Bosch, Thierry P P, van den Berg, Mike M P, Vaarwater, Jolanda, Kockx, Christel E M, Paridaens, Dion, Naus, Nicole C, Nellist, Mark, van IJcken, Wilfred F J, Kiliç, Emine, de Klein, Annelies

“…Uveal melanoma is a lethal cancer with a strong propensity to metastasize. Limited therapeutic options are available once the disease has disseminated. A…”
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Microvascular Dysfunction Is Associated With Worse Cognitive Performance: The Maastricht Study by Rensma, Sytze P., van Sloten, Thomas T., Houben, Alfons J.H.M., Köhler, Sebastian, van Boxtel, Martin P.J., Berendschot, Tos T.J.M., Jansen, Jacobus F.A., Verhey, Frans R.J., Kroon, Abraham A., Koster, Annemarie, Backes, Walter H., Schaper, Nicolaas, Dinant, Geert-Jan, Schalkwijk, Casper G., Henry, Ronald M.A., Wolfs, Elze M.L., van Heumen, Mike J.A., Schram, Miranda T., Stehouwer, Coen D.A.

“…Microvascular dysfunction may be associated with worse cognitive performance. Most previous studies did not adjust for important confounders, evaluated only…”
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Development of compact transcriptional effectors using high-throughput measurements in diverse contexts by Tycko, Josh, Van, Mike V., Aradhana, DelRosso, Nicole, Ye, Hanrong, Yao, David, Valbuena, Raeline, Vaughan-Jackson, Alun, Xu, Xiaoshu, Ludwig, Connor, Spees, Kaitlyn, Liu, Katherine, Gu, Mingxin, Khare, Venya, Mukund, Adi Xiyal, Suzuki, Peter H., Arana, Sophia, Zhang, Catherine, Du, Peter P., Ornstein, Thea S., Hess, Gaelen T., Kamber, Roarke A., Qi, Lei S., Khalil, Ahmad S., Bintu, Lacramioara, Bassik, Michael C.

“…Transcriptional effectors are protein domains known to activate or repress gene expression; however, a systematic understanding of which effector domains…”
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Activity-dependent regulation of mitochondrial motility in developing cortical dendrites by Silva, Catia AP, Yalnizyan-Carson, Annik, Fernández Busch, M Victoria, van Zwieten, Mike, Verhage, Matthijs, Lohmann, Christian

“…Developing neurons form synapses at a high rate. Synaptic transmission is very energy-demanding and likely requires ATP production by mitochondria nearby…”
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Structure-based classification of tauopathies by Shi, Yang, Zhang, Wenjuan, Yang, Yang, Murzin, Alexey G., Falcon, Benjamin, Kotecha, Abhay, van Beers, Mike, Tarutani, Airi, Kametani, Fuyuki, Garringer, Holly J., Vidal, Ruben, Hallinan, Grace I., Lashley, Tammaryn, Saito, Yuko, Murayama, Shigeo, Yoshida, Mari, Tanaka, Hidetomo, Kakita, Akiyoshi, Ikeuchi, Takeshi, Robinson, Andrew C., Mann, David M. A., Kovacs, Gabor G., Revesz, Tamas, Ghetti, Bernardino, Hasegawa, Masato, Goedert, Michel, Scheres, Sjors H. W.

“…The ordered assembly of tau protein into filaments characterizes several neurodegenerative diseases, which are called tauopathies. It was previously reported…”
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Plasticity in the Meiotic Epigenetic Landscape of Sex Chromosomes in Caenorhabditis Species by Larson, Braden J, Van, Mike V, Nakayama, Taylor, Engebrecht, JoAnne

“…During meiosis in the heterogametic sex in some species, sex chromosomes undergo meiotic sex chromosome inactivation (MSCI), which results in acquisition of…”
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Pseudosynapsis and decreased stringency of meiotic repair pathway choice on the hemizygous sex chromosome of Caenorhabditis elegans males by Checchi, Paula M, Lawrence, Katherine S, Van, Mike V, Larson, Braden J, Engebrecht, JoAnne

“…During meiosis, accurate chromosome segregation relies on homology to mediate chromosome pairing, synapsis, and crossover recombination. Crossovers are…”
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Not Yet the Post-TV Era: Network and MVPD Adaptation to Emergent Distribution Technologies by Van Esler, Mike

“…Television as a medium is in transition. From DVRs, to Netflix, to HBO Now, consumers have never before had such control over how they consume televisual…”
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To Break or Not To Break: Sex Chromosome Hemizygosity During Meiosis in Caenorhabditis by Van, Mike V, Larson, Braden J, Engebrecht, JoAnne

“…Meiotic recombination establishes connections between homologous chromosomes to promote segregation. Hemizygous regions of sex chromosomes have no homologous…”
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Adding insult to injury: Effects of chronic oxybenzone exposure and elevated temperature on two reef-building corals by Wijgerde, Tim, van Ballegooijen, Mike, Nijland, Reindert, van der Loos, Luna, Kwadijk, Christiaan, Osinga, Ronald, Murk, Albertinka, Slijkerman, Diana

“…Coral bleaching due to global warming currently is the largest threat to coral reefs, which may be exacerbated by altered water quality. Elevated levels of the…”
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Rainfall, geology and landscape position generate large-scale spatiotemporal fire pattern heterogeneity in an African savanna by Smit, Izak P. J., Smit, Chris F., Govender, Navashni, Linde, Mike van der, MacFadyen, Sandra

“…Fire is considered a critical management tool in fire prone landscapes. Often studies and policies relating to fire focus on why and how the fire regime should…”
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Uncommon breast tumors in perspective: Incidence, treatment and survival in the Netherlands by Louwman, Marieke W.J., Vriezen, Martine, Beek, Mike W.P.M. van, Nolthenius‐Puylaert, M. Cathelijne B.J.E. Tutein, Sangen, Maurice J.C. van der, Roumen, Rudi M., Kiemeney, Lambertus A.L.M., Coebergh, Jan Willem W.

“…The relatively small group of patients with breast tumors other than the ductal, lobular or mixed ducto‐lobular types, has reached nonnegligible numbers due to…”
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An Algorithm for Nonparametric Estimation of a Multivariate Mixing Distribution with Applications to Population Pharmacokinetics by Yamada, Walter M, Neely, Michael N, Bartroff, Jay, Bayard, David S, Burke, James V, Guilder, Mike van, Jelliffe, Roger W, Kryshchenko, Alona, Leary, Robert, Tatarinova, Tatiana, Schumitzky, Alan

“…Population pharmacokinetic (PK) modeling has become a cornerstone of drug development and optimal patient dosing. This approach offers great benefits for…”
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A comparison of oil supply risks in EU, US, Japan, China and India under different climate scenarios by van Moerkerk, Mike, Crijns-Graus, Wina

“…For many countries, the inflow of energy is essential to keep economies running. Oil is typically considered to be the most critical fuel as an input for the…”
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Shame on Me! Self-Conscious Emotions and Big Five Personality Traits and Their Relations to Anxiety Disorders Symptoms in Young, Non-Clinical Adolescents by Muris, Peter, Meesters, Cor, van Asseldonk, Mike

“…This study explored the relations between self-conscious emotions, personality traits, and anxiety disorders symptoms in non-clinical youths…”
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Marine mammal acoustic detections in the Greenland and Barents Sea, 2013 – 2014 seasons by De Vreese, Steffen, van der Schaar, Mike, Weissenberger, Jürgen, Erbs, Florence, Kosecka, Monika, Solé, Marta, André, Michel

“…While the Greenland and Barents Seas are known habitats for several cetacean and pinniped species there is a lack of long-term monitoring data in this rapidly…”
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